Search Results - "Shen, Mengjia"

Identification of key interferon-stimulated genes for indicating the condition of patients with systemic lupus erythematosus by Shen, Mengjia, Duan, Congcong, Xie, Changhao, Wang, Hongtao, Li, Zhijun, Li, Baiqing, Wang, Tao

“…Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with highly heterogeneous clinical symptoms and severity. There is complex pathogenesis of…”
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Molecular subtyping reveals uniqueness of prognosis in breast ductal carcinoma in situ patients with lumpectomy by Yang, Libo, Shen, Mengjia, Qiu, Yan, Tang, Tingting, Bu, Hong

“…We aimed to analyse the discrepancy in clinical features and prognosis between molecular subtypes in primary ductal carcinoma in situ (DCIS) patients with…”
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Prognostic Score-Based Stratification Analysis Reveals Universal Benefits of Radiotherapy on Lowering the Risk of Ipsilateral Breast Event for Ductal Carcinoma In Situ Patients with Different Risk Levels by Yang, Libo, Lu, Dongli, Lai, Yutian, Shen, Mengjia, Yu, Qiuxiao, Lei, Ting, Pu, Tianjie, Bu, Hong

“…Background We aimed to analyze the effects of radiotherapy (RT) on the incidence rate of ipsilateral breast event (IBE) in ductal carcinoma in situ (DCIS)…”
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Correction to: Genomic characteristics of two breast malignant phyllodes tumors during pregnancy and lactation identified through whole-exome sequencing by Lei, Ting, Shen, Mengjia, Deng, Xu, Shi, Yongqiang, Peng, Yan, Wang, Hui, Chen, Tongbing

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Repression of miR-135b-5p promotes metastasis of early-stage breast cancer by regulating downstream target SDCBP by Pu, Tianjie, Shen, Mengjia, Li, Shi, Yang, Libo, Gao, Hongwei, Xiao, Lin, Zhong, Xiaorong, Zheng, Hong, Liu, Yueping, Ye, Feng, Bu, Hong

“…Metastasis is an essential event for breast cancer (BC) progression even after initial surgery. The identification of patients with a high probability of…”
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Genomic characteristics of two breast malignant phyllodes tumors during pregnancy and lactation identified through whole-exome sequencing by Lei, Tinge, Shen, Mengjia, Deng, Xu, Shi, Yongqiang, Peng, Yan, Wang, Hui, Chen, Tongbing

“…Abstract Background The genomic landscape of breast malignant phyllodes tumors (PTs) is not well defined, especially pregnancy-related malignant PTs. To…”
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DDX58 deficiency leads to triple negative breast cancer chemotherapy resistance by inhibiting Type I IFN-mediated signalling apoptosis by Cao, Shiyu, Long, Xinyi, Xiao, Lin, Zhang, Peichuan, Shen, Mengjia, Chen, Fei, Bao, Chunjuan, Zhong, Xiaorong, Luo, Ting, Ye, Feng

“…Triple-negative breast cancer (TNBC) is characterized by its aggressive nature and absence of specific therapeutic targets, necessitating the reliance on…”
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Clinicopathological and genetic characterization of radiotherapy-induced undifferentiated pleomorphic sarcoma following breast cancer: a case series of three tumors and comprehensive literature review by Lei, Ting, Shen, Zhiyi, Shen, Mengjia, Du, Lingfang, Shi, Yongqiang, Peng, Yan, Zhou, Zidi, Da, Wenyue, Chen, Xi, Li, Qing

“…Compared to primary breast sarcoma (BSs), radiotherapy-induced sarcoma (RIS) is a less frequent type of secondary breast sarcoma. Undifferentiated pleomorphic…”
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LCZ696 (sacubitril/valsartan) inhibits pulmonary hypertension induced right ventricular remodeling by targeting pyruvate dehydrogenase kinase 4 by Shen, Mengjia, Zheng, Cankun, Chen, Lu, Li, Mingjue, Huang, Xiaoxia, He, Mingyuan, Liu, Chiyu, Lin, Hairuo, Liao, Wangjun, Bin, Jianping, Cao, Shiping, Liao, Yulin

“…Right ventricular (RV) function is a major prognostic factor in patients with cardiopulmonary disease. Effective medical therapies are available for left heart…”
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Dapagliflozin attenuates residual cardiac remodeling after surgical ventricular reconstruction in mice with an enlarged heart after myocardial infarction by Ma, Siyuan, Chen, Lu, Yan, Junyu, Shen, Mengjia, Zhang, Rui, Li, Mingjue, He, Mingyuan, Chen, Kaitong, Zhu, Yingqi, Lin, Hairuo, Wang, Yuegang, Liao, Wangjun, Bin, Jianping, Zheng, Cankun, Liao, Yulin

“…Severe heart failure refractory to conventional therapy requires alternative treatment modalities. Surgical ventricular reconstruction (SVR) has been used to…”
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DNAJC12 causes breast cancer chemotherapy resistance by repressing doxorubicin-induced ferroptosis and apoptosis via activation of AKT by Shen, Mengjia, Cao, Shiyu, Long, Xinyi, Xiao, Lin, Yang, Libo, Zhang, Peichuan, Li, Li, Chen, Fei, Lei, Ting, Gao, Hongwei, Ye, Feng, Bu, Hong

“…Chemotherapy is a primary treatment for breast cancer (BC), yet many patients develop resistance over time. This study aims to identify critical factors…”
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Bioinformatics exploration of potential common therapeutic targets for systemic and pulmonary arterial hypertension-induced myocardial hypertrophy by Chen, Lu, Li, Mingjue, Shen, Mengjia, Zhu, Yingqi, Chen, Kaitong, Huang, Xiaoxia, Zheng, Cankun, Wang, Qiancheng, Lin, Hairuo, Liao, Wangjun, Bin, Jianping, Ma, Siyuan, Liao, Yulin

“…Systemic and pulmonary arterial hypertension (PAH) can induce left and right ventricular hypertrophy, respectively, but common therapeutic targets for both…”
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CircMap4k2 reactivated by aneurysm plication alleviates residual cardiac remodeling after SVR by enhancing cardiomyocyte proliferation in post-MI mice by Yan, Junyu, Ai, Chenzhi, Chen, Qi, Wang, Qiuhan, Zhu, Yingqi, Li, Mingjue, Chen, Kaitong, He, Mingyuan, Shen, Mengjia, Chen, Lu, Zhang, Rui, Zheng, Cankun, Liao, Wangjun, Bin, Jianping, Lin, Hairuo, Ma, Siyuan, Tan, Ning, Liao, Yulin

“…[Display omitted] •This study is the first attempt to clarify the role of circRNA in surgical ventricular reconstruction (SVR).•We identified a novel circRNA,…”
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A Bibliometric and Visualized Analysis of Cardiac Regeneration Over a 20-Year Period by Ma, Siyuan, Yan, Junyu, Chen, Lu, Zhu, Yingqi, Chen, Kaitong, Zheng, Cankun, Shen, Mengjia, Liao, Yulin

“…Recent research has suggested that cardiac regeneration may have the widely applicable potential of treating heart failure (HF). A comprehensive understanding…”
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HER3: Updates and current biology function, targeted therapy and pathologic detecting methods by Gao, Leyi, Zhang, Yu, Feng, Mengna, Shen, Mengjia, Yang, Libo, Wei, Bing, Zhou, Yongjie, Zhang, Zhang

“…Being a member of the EGFR tyrosine kinase family, HER3 has been shown to be overexpressed in a number of cancers, including breast cancer (BC). The kinase…”
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Titration of sedentary behavior with varying physical activity levels reduces mortality in patients with type 2 diabetes by Liu, Jieyi, Ai, Chenzhi, Li, Zhihong, Huang, Xiaoxia, Shen, Mengjia, Zheng, Cankun, Liao, Wangjun, Bin, Jianping, Li, Jinghua, Lin, Hairuo, Guan, Ziyun, Liao, Yulin

“…Both physical activity (PA) and sedentary behavior (SB) exert important impact on type 2 diabetes, but it remains unclear how maximum impact on improving the…”
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Pregnancy-induced physiological hypertrophic preconditioning attenuates pathological myocardial hypertrophy by activation of FoxO3a by Xie, Jiahe, Zheng, Cankun, Shen, Mengjia, Lu, Weiling, Li, Mingjue, He, Mingyuan, Chen, Lu, Ma, Siyuan, Zhu, Yingqi, Lin, Hairuo, Xiu, Jiancheng, Liao, Wangjun, Bin, Jianping, Liao, Yulin

“…Previous studies show a woman’s pregnancy is correlated with post-reproductive longevity, and nulliparity is associated with higher risk of incident heart…”
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ERBB2 mRNA expression to distinguish HER2-low/neg breast cancer prognosis by Liu, Yueping, Lv, Hong, Shen, Mengjia, Shui, Ruohong, Ye, Feng, Meng, Yue, Jia, Ying, Liu, Chao, An, Shun, Yuan, Xiaoying, Li, Xingmin, Yang, Wentao, Bu, Hong

“…569 Background: Antibody-drug conjugates such as Trastuzumab deruxtecan significantly improved progression-free and overall survival for the HER2 low…”
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Clinicopathologic characteristics of HER2-positive metaplastic squamous cell carcinoma of the breast by Lei, Ting, Pu, Tianjie, Wei, Bing, Fan, Yingying, Yang, Libo, Shen, Mengjia, Chen, Min, Yang, Jieliang, Zhang, Yu, Zhang, Zhang, Bu, Hong

“…The aim of this study was to analyse the clinicopathological features and prognosis of human epidermal growth factor receptor-2 (HER2)-positive metaplastic…”
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Mediator complex subunit 16 is down-regulated in papillary thyroid cancer, leading to increased transforming growth factor-β signaling and radioiodine resistance by Gao, Hongwei, Bai, Peirong, Xiao, Lin, Shen, Mengjia, Yu, Qiuxiao, Lei, Yuanyuan, Huang, Wenting, Lin, Xiang, Zheng, Xinyi, Wei, Tao, Jiang, Yong, Ye, Feng, Bu, Hong

“…Mediator complex subunit 16 (MED16) is a component of the mediator complex and functions as a coactivator in transcriptional events at almost all RNA…”
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