Search Results - "Shen, Haowei"

Heroin relapse requires long-term potentiation-like plasticity mediated by NMDA2b-containing receptors by Shen, Haowei, Moussawi, Khaled, Zhou, Wenhua, Toda, Shigenobu, Kalivas, Peter W

“…Persistent relapse to addictive drugs constitutes the most challenging problem in addiction therapy, and is linked to impaired prefrontal cortex regulation of…”
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Inhibition of Lactate Transport Erases Drug Memory and Prevents Drug Relapse by Zhang, Yan, Xue, Yanxue, Meng, Shiqiu, Luo, Yixiao, Liang, Jie, Li, Jiali, Ai, Sizhi, Sun, Chengyu, Shen, Haowei, Zhu, Weili, Wu, Ping, Lu, Lin, Shi, Jie

“…Abstract Background Drug memories that associate drug-paired stimuli with the effects of abused drugs contribute to relapse. Exposure to drug-associated…”
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Reversing cocaine-induced synaptic potentiation provides enduring protection from relapse by Moussawi, Khaled, Zhou, Wenhua, Shen, Haowei, Reichel, Carmela M, See, Ronald E, Carr, David B, Kalivas, Peter W

“…Cocaine addiction remains without an effective pharmacotherapy and is characterized by an inability of addicts to inhibit relapse to drug use. Vulnerability to…”
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Deficits in N-Methyl-D-Aspartate Receptor Function and Synaptic Plasticity in Hippocampal CA1 in APP/PS1 Mouse Model of Alzheimer's Disease by Xu, Le, Zhou, Yiying, Hu, Linbo, Jiang, Hongde, Dong, Yibei, Shen, Haowei, Lou, Zhongze, Yang, Siyu, Ji, Yunxin, Ruan, Liemin, Zhang, Xiaoqin

“…The N-methyl-D-aspartate receptor is a critical molecule for synaptic plasticity and cognitive function. Impaired synaptic plasticity is thought to contribute…”
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Role of mGluR5 neurotransmission in reinstated cocaine-seeking by Wang, Xiusong, Moussawi, Khaled, Knackstedt, Lori, Shen, Haowei, Kalivas, Peter W.

“…ABSTRACT In animal models of addiction, reducing glutamate stimulation of the metabotropic glutamate receptor 5 (mGluR5) inhibits drug‐seeking. The present…”
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A silent synapse-based mechanism for cocaine-induced locomotor sensitization by Brown, Travis E, Lee, Brian R, Mu, Ping, Ferguson, Deveroux, Dietz, David, Ohnishi, Yoshinori N, Lin, Ying, Suska, Anna, Ishikawa, Masago, Huang, Yanhua H, Shen, Haowei, Kalivas, Peter W, Sorg, Barbara A, Zukin, R Suzanne, Nestler, Eric J, Dong, Yan, Schlüter, Oliver M

“…Locomotor sensitization is a common and robust behavioral alteration in rodents whereby following exposure to abused drugs such as cocaine, the animal becomes…”
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Fucoxanthin alleviates methamphetamine-induced neurotoxicity possibly via the inhibition of interaction between Keap1 and Nrf2 by Wei, Jiaxin, Mou, Chenye, Bao, Yongjie, Xie, Yanfei, Jin, Haixiao, Shen, Haowei, Zhou, Wenhua, Zhang, Jinrong, He, Shan, Chen, Bojun, Liu, Lin, Wu, Xiang, Yan, Xiaojun, Cui, Wei

“…[Display omitted] •• Fucoxanthin inhibits methamphetamine-induced neuronal apoptosis and oxidative stress.•• Fucoxanthin promotes Nrf2 translocation via the…”
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Benzodiazepine-Receptor Agonist Utilization in Outpatients with Anxiety Disorder: A Retrospective Study Based on Electronic Healthcare Data from a Large General Tertiary Hospital by Liu, Denong, Zhang, Qingyu, Zhao, Zhijia, Chen, Mengjia, Hou, Yanbin, Wang, Guanjun, Shen, Haowei, Zhu, Huaqiang, Ji, Yunxin, Ruan, Liemin, Lou, Zhongze

“…Benzodiazepine-receptor agonists (BZRAs), including benzodiazepines (BZDs) and drugs related to BZDs (Z-drugs), are commonly used for anxiety, but often have…”
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Automated quantification of dendritic spine density and spine head diameter in medium spiny neurons of the nucleus accumbens by Shen, Haowei, Sesack, Susan R., Toda, Shigenobu, Kalivas, Peter W.

“…Dendritic spines are postsynaptic specializations thought to regulate the strength of synaptic transmission and play a critical role in neuronal plasticity…”
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Inhibition of Actin Polymerization Prevents Cocaine-induced Changes in Spine Morphology in the Nucleus Accumbens by Toda, Shigenobu, Shen, Haowei, Kalivas, Peter W.

“…Withdrawal from daily cocaine administration causes an increase in actin cycling and increases spine head diameter in medium spiny neurons from the core of the…”
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Methamphetamine-induced locomotor activity and sensitization in dopamine transporter and vesicular monoamine transporter 2 double mutant mice by FUKUSHIMA, Setsu, HAOWEI SHEN, SORA, Ichiro, HATA, Harumi, OHARA, Arihisa, OHMI, Kayo, IKEDA, Kazutaka, NUMACHI, Yohtaro, KOBAYASHI, Hideaki, HALL, F. Scott, UHL, George R

“…The dopamine transporter (DAT) and the vesicular monoamine transporter 2 (VMAT2) play pivotal roles in the action of methamphetamine (MAP), including acute…”
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A site distance dependence of product selectivity in n-hexane dehydrogenation over alumina-supported chromium catalyst by Li, Xiuyi, Fan, Rong, Shen, Haowei, Wang, Guowei, Li, Chunyi

“…[Display omitted] •Catalytic behavior of CrOx/γ-Al2O3 in n-hexane dehydrogenation is closely related to the density of Cr sites.•Multi-point adsorption of…”
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Reinforcing and discriminative-stimulus effects of two pyrrolidine-containing synthetic cathinone derivatives in rats by Xu, Peng, Lai, Miaojun, Fu, Dan, Liu, Huifen, Wang, Youmei, Shen, Haowei, Zhou, Wenhua

“…The molecular and behavioral aspects of α-pyrrolidinopentiophenone (α-PVP) have been characterized; however, how the structural modification of α-PVP affects…”
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Glutamate transmission in addiction by Kalivas, Peter W., LaLumiere, Ryan T., Knackstedt, Lori, Shen, Haowei

“…Cortico-striatal glutamate transmission has been implicated in both the initiation and expression of addiction related behaviors, such as locomotor…”
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N-isopropylbenzylamine, a methamphetamine mimics, produces toxicity via increasing nitric oxide in vitro by Xu, Peng, Li, Haijie, Qiu, Qiyang, Xiao, Xiao, Qiu, Yi, Li, Xiangyu, Wang, Youmei, Zhou, Wenhua, Shen, Haowei, Cui, Wei

“…N-isopropylbenzylamine, an isomer of methamphetamine, has been used to adulterate methamphetamine, and distributed as fake “Ice” methamphetamine by illicit…”
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Electroconvulsive shock regulates serotonin transporter mRNA expression in rat raphe nucleus by Shen, Haowei, Numachi, Yohtaro, Yoshida, Sumiko, Toda, Shigenobu, Awata, Shuichi, Matsuoka, Hiroo, Sato, Mitsumoto

“…The antidepressive actions of electroconvulsive shock (ECS) therapy are considered to involve altered neurotransmission of serotonin. In this study, we…”
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Reduced LTP and LTD in prefrontal cortex synapses in the nucleus accumbens after heroin self-administration by Shen, Haowei, Kalivas, Peter W.

“…Addiction changes prefrontal cortex regulation of the nucleus accumbens, including reduced ability to induce long-term potentiation (LTP) and long-term…”
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Flavonoid production in tomato mediates both direct and indirect plant defences against whiteflies in tritrophic interactions by Yang, Fengbo, Shen, Haowei, Huang, Tianyu, Yao, Qixi, Hu, Jinyu, Tang, Juan, Zhang, Rong, Tong, Hong, Wu, Qingjun, Zhang, Youjun, Su, Qi

“…The role of plant flavonoids in direct defences against chewing and sap-sucking herbivorous insects has been extensively characterized. However, little is…”
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N‐Isopropylbenzylamine‐induced conditioned place preference, sensitization behaviour and self‐administration in rodents by Lai, Miaojun, Fu, Dan, Li, Xiangyu, Zhuang, Dingding, Wang, Majie, Xu, Zeming, Liu, Huifen, Shen, Haowei, Xu, Peng, Zhou, Wenhua

“…N‐Isopropylbenzylamine (N‐ipb), a chain isomer of methamphetamine (METH) with similar physical properties, has been used as a substitute for METH in seized…”
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Assessment of abuse potential of carfentanil by Wei, Jiayun, Lai, Miaojun, Li, Feng, Chen, Yuanyuan, Li, Xiangyu, Qiu, Yi, Shen, Haowei, Xu, Peng, Di, Bin

“…Carfentanil, as a fentanyl analogue, is a potent synthetic opioid. It has been controlled in many countries, and its emergence has been highlighted by many…”
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