Search Results - "Shen, Haiyuan"

Downregulation of TPX2 impairs the antitumor activity of CD8+ T cells in hepatocellular carcinoma by Wang, Xiaochen, Wang, Jianchu, Shen, Haiyuan, Luo, Zongjiang, Lu, Xiaojie

“…Targeting key genes that play dominant roles in T cell dysfunction is an efficient strategy for cancer immunotherapy. Here, we aimed to investigate the role of…”
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The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation by Zhang, Wenjie, Zhangyuan, Guangyan, Wang, Fei, Jin, Kangpeng, Shen, Haiyuan, Zhang, Liansheng, Yuan, Xiang, Wang, Jincheng, Zhang, Haitian, Yu, Weiwei, Huang, Ruyi, Xu, Xiaoliang, Yin, Yin, Zhong, Guisheng, Lin, Anning, Sun, Beicheng

“…Chronic inflammation plays a central role in hepatocellular carcinoma (HCC), but the contribution of hepatocytes to tumor-associated inflammation is not clear…”
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Endoplasmic reticulum stress in innate immune cells - a significant contribution to non-alcoholic fatty liver disease by Zhou, Liangliang, Shen, Haiyuan, Li, Xiaofeng, Wang, Hua

“…Liver disease and its complications affect millions of people worldwide. NAFLD (non-alcoholic fatty liver disease) is the liver disease associated with…”
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A dynamic taint tracking optimized fuzz testing method based on multi-modal sensor data fusion by Li, Qianmu, Liu, Yaozong, Meng, Shunmei, Zhang, Hanrui, Shen, Haiyuan, Long, Huaqiu

“…The safety of the Industrial Internet Control Systems has been a hotspot in the information security. To meet the needs of communication, a large variety of…”
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Learning deep networks with crowdsourcing for relevance evaluation by Wu, Ming, Yin, Xiaochun, Li, Qianmu, Zhang, Jing, Feng, Xinqi, Cao, Qi, Shen, Haiyuan

“…In this paper, we propose a novel relevance evaluation method using labels collected from crowdsourcing. The proposed method not only predicts the relevance…”
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A Cloud-Fog-Edge Closed-Loop Feedback Security Risk Prediction Method by Li, Qianmu, Tian, Youhui, Wu, Qiang, Cao, Qi, Shen, Haiyuan, Long, Huaqiu

“…In recent years, with the opening of the "smart age" curtain, smart devices dominated by technologies such as robots, drones, and intelligent perception have…”
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Microwave-Assisted Ablation Improves the Prognosis of Patients With Hepatocellular Carcinoma Undergoing Liver Resection by Shen, Haiyuan, Zhou, Shu, Lou, Yun, Gao, Yangjuan, Cao, Shouji, Wu, Du, Li, Guoqiang

“…Objective: We evaluated microwave-assisted liver resection for hepatocellular carcinoma. Patients and Methods: We enrolled 79 patients in this study, and…”
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Prognostic Value of Phosphotyrosine Phosphatases in Hepatocellular Carcinoma by Zhangyuan, Guangyan, Yin, Yin, Zhang, Wenjie, Yu, WeiWei, Jin, Kangpeng, Wang, Fei, Huang, Ruyi, Shen, Haiyuan, Wang, Xiaochen, Sun, Beicheng

“…Background/Aims: During the occurrence and progression of hepatocellular carcinoma (HCC), phosphotyrosine phosphatases (PTPs) are usually described as tumor…”
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TOX promotes the exhaustion of antitumor CD8+ T cells by preventing PD1 degradation in hepatocellular carcinoma by Wang, Xiaochen, He, Qifeng, Shen, Haiyuan, Xia, Anliang, Tian, Wenfang, Yu, Weiwei, Sun, Beicheng

“…[Display omitted] •TOX promotes CD8+ T cell exhaustion in hepatocellular carcinoma.•TOX impairs CD8+ T cell antitumor function and response to anti-PD1…”
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Exosomes derived from exhausted CD8+ T cells impaired the anticancer function of normal CD8+ T cells by Wang, Xiaochen, Shen, Haiyuan, He, Qifeng, Tian, Wenfang, Xia, Anliang, Lu, Xiao-Jie

“…Previous studies suggested that diverse cells in cancer microenvironment can interact with CD8+ T cells via exosomes. We designed this study to explore the…”
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853 DIETARY FIBER ALLEVIATES ALCOHOLIC LIVER INJURY VIA BACTEROIDES ACIDIFACIENS AND SUBSEQUENT AMMONIA DETOXIFICATION by Shen, Haiyuan, Shu, Hang, Wu, Dongqing, Fan, Yuanyuan, Wang, Hua, Yin, Shi

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Long non‐coding RNA LUCAT1 promotes tumourigenesis by inhibiting ANXA2 phosphorylation in hepatocellular carcinoma by Lou, Yun, Yu, Yue, Xu, Xiaolia, Zhou, Shu, Shen, Haiyuan, Fan, Tianlong, Wu, Di, Yin, Jie, Li, Guoqiang

“…Long non‐coding RNAs (lncRNAs) play essential roles in diverse biological processes; however, current understanding of the mechanism underlying the regulation…”
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14-3-3ζ delivered by hepatocellular carcinoma-derived exosomes impaired anti-tumor function of tumor-infiltrating T lymphocytes by Wang, Xiaochen, Shen, Haiyuan, Zhangyuan, Guangyan, Huang, Ruyi, Zhang, Wenjie, He, Qifeng, Jin, Kangpeng, Zhuo, Han, Zhang, Zechuan, Wang, Jincheng, Sun, Beicheng, Lu, Xiaojie

“…Increasing evidence shows that the anti-tumor functions of tumor-infiltrating T lymphocytes (TILs) were inhibited significantly, but the underlying mechanisms…”
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Genetic and phenotypic difference in CD8 + T cell exhaustion between chronic hepatitis B infection and hepatocellular carcinoma by Wang, Xiaochen, He, Qifeng, Shen, Haiyuan, Lu, Xiao-Jie, Sun, Beicheng

“…Several recent studies published have suggested that T cell exhaustion exists both in chronic infection and cancer. However, to date, few studies have…”
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Kinesin superfamily protein expression and its association with progression and prognosis in hepatocellular carcinoma by Chen, Jianliang, Li, Shu, Zhou, Shu, Cao, Shouji, Lou, Yun, Shen, Haiyuan, Yin, Jie, Li, Guoqiang

“…In this study, we characterized the expression of 32 other kinesin superfamily proteins (KIFs) and analyzed their association with the progression and…”
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Experimental models of fatty liver diseases: Status and appraisal by Wang, Hua, Shen, Haiyuan, Seo, Wonhyo, Hwang, Seonghwan

“…Fatty liver diseases, including alcohol-associated liver disease (ALD) and nonalcoholic fatty liver disease nonalcoholic fatty liver disease (NAFLD), affect a…”
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Dietary fiber alleviates alcoholic liver injury via Bacteroides acidifaciens and subsequent ammonia detoxification by Shen, Haiyuan, Zhou, Liangliang, Zhang, Hao, Yang, Yuanru, Jiang, Ling, Wu, Dongqing, Shu, Hang, Zhang, Hejiao, Xie, Linxi, Zhou, Kaichen, Cheng, Chen, Yang, Lei, Jiang, Jiali, Wang, Siya, Han, Yiran, Zhu, Jiayi, Xu, Long, Liu, Zhihua, Wang, Hua, Yin, Shi

“…The gut microbiota and diet-induced changes in microbiome composition have been linked to various liver diseases, although the specific microbes and mechanisms…”
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Mucosal-Associated Invariant T Cells in the Digestive System: Defender or Destroyer? by Zhang, Hejiao, Shen, Haiyuan, Zhou, Liangliang, Xie, Linxi, Kong, Derun, Wang, Hua

“…Mucosal-associated invariant T (MAIT) cells are a subset of innate T lymphocytes that express the semi-invariant T cell receptor and recognize riboflavin…”
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siRNA-loaded folic acid-modified TPGS alleviate MASH via targeting ER stress sensor XBP1 and reprogramming macrophages by Zhu, Manman, Cheng, Yong, Zuo, Li, Bin, Bao, Shen, Haiyuan, Meng, Tao, Wu, Zihao, Rao, Peng, Tang, Yue, Li, Shuojiao, Xu, Honghai, Sun, Guoping, Wang, Hua, Zhang, Guiyang, Liu, Jiatao

“…Macrophages show high plasticity and play a vital role in the progression of metabolic dysfunction-associated steatohepatitis (MASH). X-box binding protein 1…”
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Mucosal-Associated Invariant T Cells in the Digestive System: Defender or Destroyer?Summary by Hejiao Zhang, Haiyuan Shen, Liangliang Zhou, Linxi Xie, Derun Kong, Hua Wang

“…Mucosal-associated invariant T (MAIT) cells are a subset of innate T lymphocytes that express the semi-invariant T cell receptor and recognize riboflavin…”
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