Search Results - "Shen, D"

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Codeine Therapy in the Context of Cytochrome P450 2D6 (CYP2D6) Genotype by Crews, K R, Gaedigk, A, Dunnenberger, H M, Klein, T E, Shen, D D, Callaghan, J T, Kharasch, E D, Skaar, T C

“…Codeine is bioactivated to morphine, a strong opioid agonist, by the hepatic cytochrome P450 2D6 (CYP2D6); hence, the efficacy and safety of codeine as an…”
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Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update by Crews, K R, Gaedigk, A, Dunnenberger, H M, Leeder, J S, Klein, T E, Caudle, K E, Haidar, C E, Shen, D D, Callaghan, J T, Sadhasivam, S, Prows, C A, Kharasch, E D, Skaar, T C

“…Codeine is bioactivated to morphine, a strong opioid agonist, by the hepatic cytochrome P450 2D6 (CYP2D6); hence, the efficacy and safety of codeine are…”
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The mechanism for thermal decomposition of cellulose and its main products by Shen, D.K., Gu, S.

“…Experiment is performed to investigate the mechanism of the cellulose pyrolysis and the formation of the main products. The evolution of the gaseous products…”
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An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers by Airhart, Sophia E, Shireman, Laura M, Risler, Linda J, Anderson, Gail D, Nagana Gowda, G A, Raftery, Daniel, Tian, Rong, Shen, Danny D, O'Brien, Kevin D

“…The co-primary objectives of this study were to determine the human pharmacokinetics (PK) of oral NR and the effect of NR on whole blood nicotinamide adenine…”
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Cerebrospinal fluid and the early brain development of autism by Shen, Mark D

“…There is currently a renaissance of interest in the many functions of cerebrospinal fluid (CSF). Altered flow of CSF, for example, has been shown to impair the…”
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Transparent Wood Smart Windows: Polymer Electrochromic Devices Based on Poly(3,4‐Ethylenedioxythiophene):Poly(Styrene Sulfonate) Electrodes by Lang, Augustus W., Li, Yuanyuan, De Keersmaecker, Michel, Shen, D. Eric, Österholm, Anna M., Berglund, Lars, Reynolds, John R.

“…Transparent wood composites, with their high strength and toughness, thermal insulation, and excellent transmissivity, offer a route to replace glass for…”
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Hydrogenation and disorder in engineered black TiO2 by Liu, Lei, Yu, Peter Y, Chen, Xiaobo, Mao, Samuel S, Shen, D Z

“…A new form of TiO2 which is black in color has been shown to exhibit high efficiency for photocatalytic reactions under solar radiation [X. Chen, L. Liu, P. Y…”
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Four Shades of Brown: Tuning of Electrochromic Polymer Blends Toward High-Contrast Eyewear by Österholm, Anna M, Shen, D. Eric, Kerszulis, Justin A, Bulloch, Rayford H, Kuepfert, Michael, Dyer, Aubrey L, Reynolds, John R

“…We report a straightforward strategy of accessing a wide variety of colors through simple predictive color mixing of electrochromic polymers (ECPs). We have…”
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High Performance and Long-Term Stability in Ambiently Fabricated Segmented Solid-State Polymer Electrochromic Displays by Remmele, Julian, Shen, D. Eric, Mustonen, Tero, Fruehauf, Norbert

“…This work reports on the performance of a segmented polymer electrochromic display that was fabricated with solution-based processes in ambient atmosphere. An…”
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Defects controlled hole doping and multivalley transport in SnSe single crystals by Wang, Zhen, Fan, Congcong, Shen, Zhixuan, Hua, Chenqiang, Hu, Qifeng, Sheng, Feng, Lu, Yunhao, Fang, Hanyan, Qiu, Zhizhan, Lu, Jiong, Liu, Zhengtai, Liu, Wanling, Huang, Yaobo, Xu, Zhu-An, Shen, D. W., Zheng, Yi

“…SnSe is a promising thermoelectric material with record-breaking figure of merit. However, to date a comprehensive understanding of the electronic structure…”
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Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport by Yeung, Catherine K, Shen, Danny D, Thummel, Kenneth E, Himmelfarb, Jonathan

“…The pharmacokinetics of non-renally cleared drugs in patients with chronic kidney disease is often unpredictable. Some of this variability may be due to…”
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Longitudinal pattern of regional brain volume change differentiates normal aging from MCI by DRISCOLL, I, DAVATZIKOS, C, AN, Y, WU, X, SHEN, D, KRAUT, M, RESNICK, S. M

“…Neuroimaging measures have potential as surrogate markers of disease through identification of consistent features that occur prior to clinical symptoms…”
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High gain Ga₂O₃ solar-blind photodetectors realized via a carrier multiplication process by Hu, G C, Shan, C X, Zhang, Nan, Jiang, M M, Wang, S P, Shen, D Z

“…Ga2O3 photodetectors with interdigitated electrodes have been designed and fabricated, and the Ga2O3 area exposed to illumination acts as the active layer of…”
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Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: Role of circulating active metabolites by Lalovic, Bojan, Kharasch, Evan, Hoffer, Christine, Risler, Linda, Liu‐Chen, Lee‐Yuan, Shen, Danny D.

“…Background In vitro experiments suggest that circulating metabolites of oxycodone are opioid receptor agonists. Clinical and animal studies to date have failed…”
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Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15 by Hsu, Jer-Yuan, Crawley, Suzanne, Chen, Michael, Ayupova, Dina A., Lindhout, Darrin A., Higbee, Jared, Kutach, Alan, Joo, William, Gao, Zhengyu, Fu, Diana, To, Carmen, Mondal, Kalyani, Li, Betty, Kekatpure, Avantika, Wang, Marilyn, Laird, Teresa, Horner, Geoffrey, Chan, Jackie, McEntee, Michele, Lopez, Manuel, Lakshminarasimhan, Damodharan, White, Andre, Wang, Sheng-Ping, Yao, Jun, Yie, Junming, Matern, Hugo, Solloway, Mark, Haldankar, Raj, Parsons, Thomas, Tang, Jie, Shen, Wenyan D., Alice Chen, Yu, Tian, Hui, Allan, Bernard B.

“…GDNF receptor alpha-like is a brainstem-restricted receptor for growth and differentiation factor 15, regulating appetite and body weight in non-homeostatic…”
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The pyrolytic degradation of wood-derived lignin from pulping process by Shen, D.K., Gu, S., Luo, K.H., Wang, S.R., Fang, M.X.

“…Lignin is a key component in the biomass with a complex polymeric structure of the phenyl-C3 alkyl units. The kraft lignin from the wood pulping process is…”
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Development of a microphysiological model of human kidney proximal tubule function by Weber, Elijah J, Chapron, Alenka, Chapron, Brian D, Voellinger, Jenna L, Lidberg, Kevin A, Yeung, Catherine K, Wang, Zhican, Yamaura, Yoshiyuki, Hailey, Dale W, Neumann, Thomas, Shen, Danny D, Thummel, Kenneth E, Muczynski, Kimberly A, Himmelfarb, Jonathan, Kelly, Edward J

“…The kidney proximal tubule is the primary site in the nephron for excretion of waste products through a combination of active uptake and secretory processes…”
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Sleep, cerebrospinal fluid, and the glymphatic system: A systematic review by Chong, Pearlynne L.H., Garic, Dea, Shen, Mark D., Lundgaard, Iben, Schwichtenberg, Amy J.

“…Current theories of the glymphatic system (GS) hypothesize that it relies on cerebrospinal fluid (CSF) circulation to disseminate growth factors and remove…”
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Baicalin decreases SGK1 expression in the hippocampus and reverses depressive-like behaviors induced by corticosterone by Li, Y.-C, Wang, L.-L, Pei, Y.-Y, Shen, J.-D, Li, H.-B, Wang, B.-Y, Bai, M

“…Highlights • Baicalin prevents depressive-like behaviors induced by CORT. • Baicalin reverses the increased mRNA and protein expression of SGK1 in the…”
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Cost-Effective, Flexible, and Colorful Dynamic Displays: Removing Underlying Conducting Layers from Polymer-Based Electrochromic Devices by Howard, Elin L, Österholm, Anna M, Shen, D. Eric, Panchumarti, L. Prerana, Pinheiro, Carlos, Reynolds, John R

“…Electrochromic (EC) materials and devices provide a user-controlled, dynamic way of displaying information using low power, making them interesting for a range…”
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