Search Results - "Shen, Aiguo"

SIRT1 antagonizes liver fibrosis by blocking hepatic stellate cell activation in mice by Li, Min, Hong, Wenxuan, Hao, Chenzhi, Li, Luyang, Wu, Dongmei, Shen, Aiguo, Lu, Jun, Zheng, Yuanlin, Li, Ping, Xu, Yong

“…Hepatic stellate cells (HSCs) are a maj or source of fibrogenesis in the liver, contributing to cirrhosis. When activated, HSCs transdifferentiate into…”
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Author Correction: Multi-omics analysis of macrophage-associated receptor and ligand reveals a strong prognostic signature and subtypes in hepatocellular carcinoma by Zhao, Yulou, Chen, Cong, Chen, Kang, Sun, Yanjun, He, Ning, Zhang, Xiubing, Xu, Jian, Shen, Aiguo, Zhao, Suming

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Multi-omics analysis of macrophage-associated receptor and ligand reveals a strong prognostic signature and subtypes in hepatocellular carcinoma by Zhao, Yulou, Chen, Cong, Chen, Kang, Sun, Yanjun, He, Ning, Zhang, Xiubing, Xu, Jian, Shen, Aiguo, Zhao, Suming

“…Hepatocellular carcinoma (HCC) is a significant contributor to morbidity and mortality worldwide. The interaction between receptors and ligands is the primary…”
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A pan-cancer analysis of anti-proliferative protein family genes for therapeutic targets in cancer by Zhang, Siming, Gu, Jue, Shi, Ling-ling, Qian, Bo, Diao, Xun, Jiang, Xiaohui, Wu, Jindong, Wu, Zhijun, Shen, Aiguo

“…The recently discovered APRO (anti-proliferative protein) family encodes a group of trans-membrane glycoproteins and includes 6 members: TOB1, TOB2, BTG1,…”
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Myocardin related transcription factor A programs epigenetic activation of hepatic stellate cells by Tian, Wenfang, Hao, Chenzhi, Fan, Zhiwen, Weng, Xinyu, Qin, Hao, Wu, Xiaoyan, Fang, Mingming, Chen, Qi, Shen, Aiguo, Xu, Yong

“…Background & Aims Activation of hepatic stellate cells (HSCs) represents a key process in liver injury and, in the absence of intervention, leads to…”
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M2M energy saving strategy in 5G millimeter wave system by Shen, Aiguo, Ye, Qiubo, Yang, Guangsong, Hao, Xinyu

“…Machine to Machine technology has a broad application prospect in the 5G network, but there is a bottleneck in the energy consumption of intelligent devices…”
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Based on the Development and Verification of a Risk Stratification Nomogram: Predicting the Risk of Lung Cancer-Specific Mortality in Stage IIIA-N2 Unresectable Large Cell Lung Neuroendocrine Cancer Compared With Lung Squamous Cell Cancer and Lung Adenocarcinoma by Yang, Ying, Shen, Cheng, Shao, Jingjing, Wang, Yilang, Wang, Gaoren, Shen, Aiguo

“…Background The purpose of this study is to predict overall survival (OS) and lung cancer-specific survival (LCSS) in patients with stage IIIA-N2 unresectable…”
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Succinylation-associated lncRNA signature to predict the prognosis of colon cancer based on integrative bioinformatics analysis by Zhang, Si-ming, Shen, Cheng, Gu, Jue, Li, Jing, Jiang, Xiaohui, Wu, Zhijun, Shen, Aiguo

“…Colon cancer (CC) has a poor 5-year survival rate though the treatment techniques and strategies have been improved. Succinylation and long noncoding RNAs…”
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A “turn-off” SERS-based detection platform for ultrasensitive detection of thrombin based on enzymatic assays by Wu, Zitong, Liu, Yizhen, Zhou, Xiaodong, Shen, Aiguo, Hu, Jiming

“…Herein we describe a novel “turn-off” biosensing strategy for thrombin detection based on Surface Enhanced Raman scattering (SERS) and the mediation of spacing…”
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PIASy mediates hypoxia-induced SIRT1 transcriptional repression and epithelial-to-mesenchymal transition in ovarian cancer cells by Sun, Lina, Li, He, Chen, Junliang, Iwasaki, Yasumasa, Kubota, Toru, Matsuoka, Mayumi, Shen, Aiguo, Chen, Qi, Xu, Yong

“…Epithelial-mesenchymal transition (EMT) has an essential role in organogenesis and contributes to a host of pathologies, including carcinogenesis. Hypoxia (low…”
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A SUMOylation-Dependent Pathway Regulates SIRT1 Transcription and Lung Cancer Metastasis by LINA SUN, HE LI, AIGUO SHEN, YONG XU, JUNLIANG CHEN, DEHENNAUT, Vanessa, YUHAO ZHAO, YUYU YANG, IWASAKI, Yasumasa, KAHN-PERLES, Brigitte, LEPRINCE, Dominique, QI CHEN

“…Epithelial-to-mesenchymal transition (EMT) plays a pivotal role in lung cancer metastasis. The class III deacetylase sirtuin 1 (SIRT1) possesses both pro- and…”
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Role of cuproptosis-related gene in lung adenocarcinoma by Liu, Yuan, Lin, Wei, Yang, Ying, Shao, JingJing, Zhao, Hongyu, Wang, Gaoren, Shen, Aiguo

“…Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer, which is the leading cause of cancer death. Dysregulation of cell proliferation and death…”
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Hough Transform-Based Large Dynamic Reflection Coefficient Micro-Motion Target Detection in SAR by Zhou, Yang, Bi, Daping, Shen, Aiguo, Wang, Xiaoping, Wang, Shuliang

“…Special phase modulation of SAR echoes resulted from target rotation or vibration, is a phenomenon called the micro-Doppler (m-D) effect. Such an effect offers…”
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Nuclear Targeted Nanoprobe for Single Living Cell Detection by Surface-Enhanced Raman Scattering by Xie, Wei, Wang, Li, Zhang, Yuying, Su, Le, Shen, Aiguo, Tan, Jinquan, Hu, Jiming

“…We present a novel nuclear targeting nanoprobe based on peptide functionalized gold nanoparticles and its surface-enhanced Raman scattering (SERS) in living…”
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PPARγ agonist pioglitazone inhibits microglia inflammation by blocking p38 mitogen-activated protein kinase signaling pathways by Ji, Huoyan, Wang, Huimin, Zhang, Fupeng, Li, Xiaohong, Xiang, Lu, Aiguo, Shen

“…Objective The aim of this paper was to investigate the inhibitory effect of peroxisome proliferator-activated receptor-gamma (PPARγ) agonist pioglitazone on…”
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Catalytic Strategy for Efficient Degradation of Nitroaromatic Pesticides by Using Gold Nanoflower by Mao, Kang, Chen, Yinran, Wu, Zitong, Zhou, Xiaodong, Shen, Aiguo, Hu, Jiming

“…In this contribution, we report a new type of Au nanoflower-based nitroaromatic pesticide degradation platform that is fast, efficient, and simple. We found a…”
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Hyper-O-GlcNAcylation of YB-1 affects Ser102 phosphorylation and promotes cell proliferation in hepatocellular carcinoma by Liu, Qingqing, Tao, Tao, Liu, Fang, Ni, Runzhou, Lu, Cuihua, Shen, Aiguo

“…As an essential post-translational modification, O-GlcNAcylation has been thought to be able to modulate various nuclear and cytoplasmic proteins and is…”
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Identification and Validation of Necroptosis-Related LncRNA Signature in Hepatocellular Carcinoma for Prognosis Estimation and Microenvironment Status by Chen, Cong, Wu, Yumeng, Chen, Kang, Xia, Zicong, Liu, Xiaokan, Zhang, Chaojie, Zhao, Hui, Shen, Aiguo

“…Background: Hepatocellular carcinoma (HCC) is among malignancies with the highest fatality toll globally and minimal therapeutic options. Necroptosis is a…”
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Comprehensive Analysis of Glutamate-Rich WD Repeat-Containing Protein 1 and Its Potential Clinical Significance for Pancancer by Wu, Yumeng, Wu, Xuming, Li, Yuanyuan, Zhao, Wenjing, Yue, Yanping, Wu, Biao, Liu, Jibin, Chen, Xudong, Shen, Aiguo

“…Background and Objective. Glutamate-rich WD repeat-containing protein 1 (GRWD1), as a novel CDT1-binding protein, plays a critical role in the initial stage of…”
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β2-adrenergic receptor signaling promotes pancreatic ductal adenocarcinoma (PDAC) progression through facilitating PCBP2-dependent c-myc expression by Wan, Chunhua, Gong, Chen, Zhang, Haifeng, Hua, Lu, Li, Xiaohong, Chen, Xudong, Chen, Yinji, Ding, Xiaoling, He, Song, Cao, Wei, Wang, Yingying, Fan, Shaoqing, Xiao, Ying, Zhou, Guoxiong, Shen, Aiguo

“…Highlights • Activated β2-AR interacts with PCBP2 in pancreatic cancer cells. • β2-AR promotes c-myc expression in PDAC cells in a PCBP2-dependent manner. •…”
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