Search Results - "Shen, A. Dong"

Drug Clearance in Neonates: A Combination of Population Pharmacokinetic Modelling and Machine Learning Approaches to Improve Individual Prediction by Tang, Bo-Hao, Guan, Zheng, Allegaert, Karel, Wu, Yue-E., Manolis, Efthymios, Leroux, Stephanie, Yao, Bu-Fan, Shi, Hai-Yan, Li, Xiao, Huang, Xin, Wang, Wen-Qi, Shen, A.-Dong, Wang, Xiao-Ling, Wang, Tian-You, Kou, Chen, Xu, Hai-Yan, Zhou, Yue, Zheng, Yi, Hao, Guo-Xiang, Xu, Bao-Ping, Thomson, Alison H., Capparelli, Edmund V., Biran, Valerie, Simon, Nicolas, Meibohm, Bernd, Lo, Yoke-Lin, Marques, Remedios, Peris, Jose-Esteban, Lutsar, Irja, Saito, Jumpei, Burggraaf, Jacobus, Jacqz-Aigrain, Evelyne, van den Anker, John, Zhao, Wei

“…Background Population pharmacokinetic evaluations have been widely used in neonatal pharmacokinetic studies, while machine learning has become a popular…”
Get full text

Insight into Population Structure and Drug Resistance of Pediatric Tuberculosis Strains from China and Russia Gained through Whole-Genome Sequencing by Zhdanova, Svetlana, Jiao, Wei-Wei, Sinkov, Viacheslav, Khromova, Polina, Solovieva, Natalia, Mushkin, Alexander, Mokrousov, Igor, Belopolskaya, Olesya, Masharsky, Aleksey, Vyazovaya, Anna, Rychkova, Lubov, Kolesnikova, Lubov, Zhuravlev, Viacheslav, Shen, A-Dong, Ogarkov, Oleg

“…This study aimed to determine phenotypic and genotypic drug resistance patterns of strains from children with tuberculosis (TB) in China and Russia, two…”
Get full text

The clinical significance of macrolide resistance in pediatric Mycoplasma pneumoniae infection during COVID-19 pandemic by Jiang, Ting-Ting, Sun, Lin, Wang, Tian-Yi, Qi, Hui, Tang, He, Wang, Ya-Cui, Han, Qian, Shi, Xiao-Qing, Bi, Jing, Jiao, Wei-Wei, Shen, A-Dong

“…(MP) is a commonly occurring pathogen causing community-acquired pneumonia (CAP) in children. The global prevalence of macrolide-resistant MP (MRMP) infection,…”
Get full text

Population pharmacokinetics-pharmacodynamics of ceftazidime in neonates and young infants: Dosing optimization for neonatal sepsis by Li, Xue, Qi, Hui, Jin, Fei, Yao, Bu-Fan, Wu, Yue-E, Qi, Yu-Jie, Kou, Chen, Wu, Xi-Rong, Luo, Xiao-Jing, Shen, Yan-Hua, Zheng, Xu, Wang, Yong-Hong, Xu, Fang, Jiao, Wei-Wei, Li, Jie-Qiong, Xiao, Jing, Dong, Yi-Ning, Du, Bin, Shi, Hai-Yan, Xu, Bao-Ping, Shen, A-Dong, Zhao, Wei

“…Ceftazidime is a third-generation cephalosporin with high activity against many pathogens. But the ambiguity and diversity of the dosing regimens in neonates…”
Get full text

Multiple Cross Displacement Amplification Combined With Real-Time Polymerase Chain Reaction Platform: A Rapid, Sensitive Method to Detect Mycobacterium tuberculosis by Jiao, Wei-Wei, Wang, Gui-Rong, Sun, Lin, Xiao, Jing, Li, Jie-Qiong, Wang, Ya-Cui, Quan, Shu-Ting, Huang, Hai-Rong, Shen, A-Dong

“…In this study, we evaluated the diagnostic accuracy of multiple cross displacement amplification (MCDA) combined with real-time PCR platform in pulmonary…”
Get full text

Systematic review of efficacy, safety and pharmacokinetics of intravenous and intraventricular vancomycin for central nervous system infections by Liu, Shu-Ping, Xiao, Jing, Liu, Ya-Li, Wu, Yue-E, Qi, Hui, Wang, Zhuang-Zhuang, Shen, A-Dong, Liu, Gang, Zhao, Wei

“…The decision of vancomycin dosage for central nervous system (CNS) infections is still a challenge because its bactericidal nature in cerebrospinal fluid (CSF)…”
Get full text

Russian “Successful” Clone B0/W148 of Mycobacterium tuberculosis Beijing Genotype: a Multiplex PCR Assay for Rapid Detection and Global Screening by MOKROUSOV, Igor, NARVSKAYA, Olga, VYAZOVAYA, Anna, OTTEN, Tatiana, JIAO, Wei-Wei, GOMES, Lia Lima, SUFFYS, Philip N, SHEN, A-Dong, VISHNEVSKY, Boris

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

A microscale HPLC‐UV method for the determination of latamoxef in plasma: An adapted method for therapeutic drug monitoring in neonates by Dong, Qian, Shi, Hai‐Yan, Kou, Chen, Huang, Xin, Shen, A‐Dong, Zhao, Wei

“…Latamoxef, a broad‐spectrum anti‐bacterial agent of the β‐lactam antibiotics, is used off‐label in treatment of neonatal sepsis. Large inter‐individual…”
Get full text

Meropenem for children with severe pneumonia: Protocol for a randomized controlled trial by Tian, Xue, Dong, Lei, Jiang, Ting-Ting, Tang, Bo-Hao, Wang, Ze-Ming, Wu, Yue-E, You, Dian-Ping, Bi, Jing, Qian, Su-Yun, Qi, Hui, Shen, A-Dong

“…Background: Pneumonia, caused by infection or other factors, seriously endangers the health of children. Meropenem is an effective broad-spectrum antibiotic…”
Get full text

Impact of glutathione S-transferase M1 and T1 on anti-tuberculosis drug-induced hepatotoxicity in Chinese pediatric patients by Liu, Fang, Jiao, An-xia, Wu, Xi-rong, Zhao, Wei, Yin, Qing-qin, Qi, Hui, Jiao, Wei-wei, Xiao, Jing, Sun, Lin, Shen, Chen, Tian, Jian-ling, Shen, Dan, Jacqz-Aigrain, Evelyne, Shen, A-dong

“…Anti-tuberculosis drug induced hepatotoxicity (ATDH) is a major adverse drug reaction associated for anti-tuberculosis therapy. The glutathione S-transferases…”
Get full text

Developmental Population Pharmacokinetics-Pharmacodynamics of Meropenem in Chinese Neonates and Young Infants: Dosing Recommendations for Late-Onset Sepsis by Wu, Yue-E, Kou, Chen, Li, Xue, Tang, Bo-Hao, Yao, Bu-Fan, Hao, Guo-Xiang, Zheng, Yi, van den Anker, John, You, Dian-Ping, Shen, A-Dong, Zhao, Wei

“…The pharmacokinetic (PK) studies of meropenem in Chinese newborns with late-onset sepsis (LOS) are still lacking. Causative pathogens of LOS and their…”
Get full text

Evolutionary History and Ongoing Transmission of Phylogenetic Sublineages of Mycobacterium tuberculosis Beijing Genotype in China by Yin, Qing-qin, Liu, Hai-can, Jiao, Wei-wei, Li, Qin-jing, Han, Rui, Tian, Jian-ling, Liu, Zhi-guang, Zhao, Xiu-qin, Li, Ying-jia, Wan, Kang-lin, Shen, A-dong, Mokrousov, Igor

“…Mycobacterium tuberculosis Beijing genotype originated in China and has undergone a dramatic population growth and global spread in the last century. Here, a…”
Get full text

Development and Clinical Validation of Multiple Cross Displacement Amplification Combined With Nanoparticles-Based Biosensor for Detection of Mycobacterium tuberculosis: Preliminary Results by Jiao, Wei-Wei, Wang, Yi, Wang, Gui-Rong, Wang, Ya-Cui, Xiao, Jing, Sun, Lin, Li, Jie-Qiong, Wen, Shu-An, Zhang, Ting-Ting, Ma, Qi, Huang, Hai-Rong, Shen, A-Dong

“…Tuberculosis is still a major threat to global public health. Here, a novel diagnosis assay, termed as multiple cross displacement amplification combined with…”
Get full text

Genetic contribution of CISH promoter polymorphisms to susceptibility to tuberculosis in Chinese children by Sun, Lin, Jin, Ya-qiong, Shen, Chen, Qi, Hui, Chu, Ping, Yin, Qing-qin, Li, Jie-qiong, Tian, Jian-ling, Jiao, Wei-wei, Xiao, Jing, Shen, A-dong

“…Tuberculosis (TB) is the leading cause of death due to an infectious disease worldwide, particularly in developing countries. A series of candidate genes have…”
Get full text

A functional promoter polymorphism of IFITM3 is associated with susceptibility to pediatric tuberculosis in Han Chinese population by Shen, Chen, Wu, Xi-rong, Jiao, Wei-wei, Sun, Lin, Feng, Wei-xing, Xiao, Jing, Miao, Qing, Liu, Fang, Yin, Qing-qin, Zhang, Chen-guang, Guo, Ya-jie, Shen, A-dong

“…A susceptibility locus for tuberculosis, a re-emerging infectious disease throughout the world, was previously discovered to exist on chromosome 11p15. IFITM3…”
Get full text

Performance of the Interferon Gamma Release Assays in Tuberculosis Disease in Children Five Years Old or Less by Sun, Lin, Tian, Jian-ling, Yin, Qing-qin, Xiao, Jing, Li, Jie-qiong, Guo, Ya-jie, Feng, Guo-shuang, Peng, Xiao-xia, Qi, Hui, Xu, Fang, Jiao, Wei-wei, Shen, Chen, Shen, A-dong

“…Interferon Gamma Release Assays (IGRAs) were developed for the indirect or immunologic diagnosis of tuberculosis infection; however, they have also been used…”
Get full text

Latamoxef for Neonates With Early-Onset Neonatal Sepsis: A Study Protocol for a Randomized Controlled Trial by Qi, Hui, Wu, Yue-E, Liu, Ya-Li, Kou, Chen, Wang, Ze-Ming, Peng, Xiao-Xia, Chen, Liang, Cui, Hong, Wang, Ya-Juan, Li, Jie-Qiong, Zhao, Wei, Shen, A-Dong

“…Early-onset neonatal sepsis (EONS), a bacterial infection that occurs within 72 h after birth, is associated with high likelihood of neonatal mortality…”
Get full text

Prevalence and molecular characteristics of drug-resistant Mycobacterium tuberculosis in Beijing, China: 2006 versus 2012 by Yin, Qing-Qin, Jiao, Wei-Wei, Li, Qin-Jing, Xu, Fang, Li, Jie-Qiong, Sun, Lin, Li, Ying-Jia, Huang, Hai-Rong, Shen, A-Dong

“…As the epidemic of MDR-TB and XDR-TB becomes increasingly severe, it is important to determine the clinical characteristics and molecular epidemiology of…”
Get full text

Epidemiology and mechanism of drug resistance of Mycoplasma pneumoniae in Beijing, China: A multicenter study by Guo, Dong-Xing, Hu, Wen-Juan, Wei, Ran, Wang, Hong, Xu, Bao-Ping, Zhou, Wei, Ma, Shao-Jie, Huang, Hui, Qin, Xuan-Guang, Jiang, Yue, Dong, Xiao-Pei, Fu, Xiao-Yan, Shi, Da-Wei, Wang, Liang-Yu, Shen, A-Dong, Xin, De-Li

“…Mycoplasma pneumoniae (M. pneumoniae) is one of the most common causes of community-acquired respiratory tract infections (RTIs). We aimed to investigate the…”
Get full text

Clinical and Drug Resistance Characteristics of New Pediatric Tuberculosis Cases in Northern China by Wang, Ting, Dong, Fang, Li, Qin-Jing, Yin, Qing-Qin, Song, Wen-Qi, Mokrousov, Igor, Jiao, Wei-Wei, Shen, A-Dong

“…The aim of this study was to evaluate the clinical features and characteristics of drug resistance in newly diagnosed pediatric tuberculosis (TB) patients in…”
Get more information