Search Results - "Shemyakin, I. G."

The use of 4-Hexylresorcinol as antibiotic adjuvant by Nikolaev, Y A, Tutel'yan, A V, Loiko, N G, Buck, J, Sidorenko, S V, Lazareva, I, Gostev, V, Manzen'yuk, O Y, Shemyakin, I G, Abramovich, R A, Huwyler, J, El'-Registan, G I

“…Ever decreasing efficiency of antibiotic treatment due to growing antibiotic resistance of pathogenic bacteria is a critical issue in clinical practice. The…”
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Pseudomonas veronii strain 7–41 degrading medium-chain n-alkanes and polycyclic aromatic hydrocarbons by Mullaeva, S. A., Delegan, Ya. A., Streletskii, R. A., Sazonova, O. I., Petrikov, K. V., Ivanova, A. A., Dyatlov, I. A., Shemyakin, I. G., Bogun, A. G., Vetrova, A. A.

“…Pollution of the environment by crude oil and oil products (represented by various types of compounds, mainly aliphatic, mono- and polyaromatic hydrocarbons)…”
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Next-Generation Antibiotics, Bacteriophage Endolysins, and Nanomaterials for Combating Pathogens by Shemyakin, I. G., Firstova, V. V., Fursova, N. K., Abaev, I. V., Filippovich, S. Yu, Ignatov, S. G., Dyatlov, I. A.

“…This review presents various strategies to fight causative agents of infectious diseases. Species-specific programmable RNA-containing antibiotics open up new…”
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Antibiotic Adjuvant 4-Hexylresorcinol Enhances the Efficiency of Antituberculosis Drugs by Nikolaev, Yu. A., Mukhina, T. N., Potapov, V. D., Kuznetsov, B. B., El’-Registan, G. I., Firstova, V. V., Shemyakin, I. G., Manzenyuk, O. Yu

“…We studied the possibility of using 4-hexylresorcinol to increase the efficiency of anti-mycobacterial chemotherapy. In an in vitro experiment,…”
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Stress-Tolerant Dormant Bacterial Forms: Biological and Ultrastructural Properties of Moraxella catarrhalis and Kocuria rhizophila by Manzenyuk, O. Yu, Suzina, N. E., Nikolaev, Yu. A., Mukhina, T. N., Firstova, V. V., El’-Registan, G. I., Shemyakin, I. G., Dyatlov, I. A.

“…Dormant forms of causative agents of healthcare-acquired infections Moraxella catarrhalis and Kocuria rhizophila have been obtained. Dormant forms cells…”
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Association of specific mutations in katG, rpoB, rpsL and rrs genes with spoligotypes of multidrug-resistant Mycobacterium tuberculosis isolates in Russia by Lipin, M.Y., Stepanshina, V.N., Shemyakin, I.G., Shinnick, T.M.

“…Most multidrug-resistant (MDR) Mycobacterium tuberculosis isolates in Russia belong to the Beijing or Latino-American and Mediterranean (LAM) spoligotype…”
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Development and testing of an enzyme immunoassay-based monoclonal test system for the detection of the Yersinia pestis V antigen by Ivaschenko, T. A, Belova, E. V, Dentovskaya, S. V, Belkova, S. A, Balakhonov, S. V, Ignatov, S. G, Shemyakin, I. G

“…An enzyme immunoassay-based test system for Y. pestis V antigen detection was developed. The specificity and sensitivity of this system met the requirements…”
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Role of Structure-Based Changes due to Somatic Mutation in Highly Homologous DNA-Binding and DNA-Hydrolyzing Autoantibodies Exemplified by A23P Substitution in the VH Domain by Kozyr, A. V., Kolesnikov, A. V., Khlyntseva, A. E., Bogun, A. G., Savchenko, G. A., Shemyakin, I. G., Gabibov, A. G.

“…Anti-DNA autoantibodies are responsible for tissue injury in lupus. A subset of DNA-specific antibodies capable of DNA cleavage can be even more harmful after…”
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Optimization of Electrofusion Parameters for Producing Hybridomas Synthesizing Human Monoclonal Antibodies by Silkina, M. V., Kartseva, A. S., Ryabko, A. K., Marin, M. A., Romanenko, Ya. O., Kalmantaeva, O. V., Khlyntseva, A. E., Shemyakin, I. G., Dyatlov, I. A., Firstova, V. V.

“…Monoclonal antibodies are an established treatment for many illnesses, including cancer, toxicity and infectious diseases. The goal of this work was to…”
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Design of a test system based on magnetic particles with immobilized monoclonal antibodies for selective Bacillus anthracis spore concentration by Khlyntseva, A. E, Belova, E. V, Zharnikova, I. V, Tyumentseva, I. S, Kulichenko, A. N, Dyatlov, I. A, Shemyakin, I. G

“…Magnetic immunosorbents (MIS) have been designed using antianthrax monoclonal antibodies immobilized on aluminum silicate—iron oxide matrix activated by sodium…”
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Monoclonal Antibodies Capable of Inhibiting the Interaction of the Receptor Binding Domain of SARS-CoV-2 Virus with the Angiotensin-Converting Receptor 2 of Human Cells by Ivashchenko, T. A., Romanenko, Ya. O., Kartseva, A. S., Silkina, M. V., Mar’in, M. A., Khlyntseva, A. E., Zeninskaya, N. A., Shemyakin, I. G., Firstova, V. V.

“…The aim of the work was to evaluate the ability of monoclonal antibodies to inhibit the interaction of the receptor binding domain (RBD) in S protein of…”
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Current understanding of Bacillus anthracis toxin molecules organization and approaches for blocking their cytotoxic action by Firstova, V. V., Shemyakin, I. G., Dyatlov, I. A.

“…Here, we review the data on mechanisms inhibiting cytotoxic effect of anthrax toxin on the immune system cells. Various disease forms, immunopathogenesis and…”
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Effect of 4-Hexylresorcinol on the Efficiency of Antibiotic Treatment of Experimental Sepsis Caused by Antibiotic-Resistant Klebsiella pneumoniae Strain in Mice by Shemyakin, I. G., Manzenyuk, O. Yu, El’-Registan, G. I., Firstova, V. V., Kombarova, T. I., Gneusheva, T. Yu, Kyazimov, E. I., Nikolaev, Yu. A.

“…High efficiency of a combined preparation including synergistic polymyxin B and 4-hexylresorcinol was shown for treatment of experimental sepsis caused by an…”
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Production and Characterization of Rat Monoclonal Antibodies against the PAL Antigen of Legionella spp by Zeninskaya, N. A., Riabko, A. K., Marin, M. A., Kombarova, T. I., Mitsevich, I. P., Yeruslanov, B. V., Firstova, V. V., Shemyakin, I. G.

“…The purpose of this work was to obtain genus-specific monoclonal antibodies against the Legionella spp. recombinant PAL protein, which will subsequently allow…”
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Characterization of the C6D7-RBD Human Monoclonal Antibody Specific to the SARS-CoV-2 S Protein Receptor-Binding Domain by Romanenko, Ya O, Silkina, M V, Kartseva, A S, Marin, M A, Shkuratova, M A, Makarova, M A, Ryabko, A K, Konyshkova, D A, Zeninskaya, N A, Khlyntseva, A E, Shemyakin, I G, Firstova, V V

“…The new coronavirus infection COVID-19 is an acute viral disease that affects primarily the upper respiratory tract. The etiological agent of COVID-19 is the…”
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Identification of wild-type Mycobacterium tuberculosis isolates and point mutations associated with isoniazid resistance by Limanskaya, O. Yu, Mukhina, T. N, Stepanshina, V. N, Shemyakin, I. G, Wu, X, Zhang, J, Fesenko, T. V, Pokrovskiy, V. A, Limanskii, A. P

“…Isoniazid resistance in Mycobacterium tuberculosis (MBT) is associated with point mutations in codon 315 of the katG gene. Two PCR technique were developed for…”
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Mechanism of Action of Monoclonal Antibodies That Block the Activity of the Lethal Toxin of Bacillus Anthracis by Romanenko, Ya O, Riabko, A K, Marin, M A, Kartseva, A S, Silkina, M V, Shemyakin, I G, Firstova, V V

“…Neutralization of the lethal toxin of Bacillus anthracis is an important topic of both fundamental medicine and practical health care, regarding the fight…”
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Characterization of drug-resistant isolates of Mycobacterium tuberculosis derived from Russian inmates by Shemyakin, I G, Stepanshina, V N, Ivanov, I Y, Lipin, M Y, Anisimova, V A, Onasenko, A G, Korobova, O V, Shinnick, T M

“…SETTING: Tuberculosis ward of a prison in Russia.OBJECTIVE: Molecular characterization of drug-resistant isolates.DESIGN: Isolates were collected from all…”
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Detecting specific memory t and b cells in volunteers annually revaccinated with live anthrax vaccine by Firstova, V. V., Kartseva, A. S., Silkina, M. V., Marin, M. A., Muntian, Ia. O., Ryabko, A. K., Shemyakin, I. G.

“…Currently, live anthrax vaccine has been used for vaccine prophylaxis in Russia and neighbor countries for seve ral decades, but precise mechanism of…”
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Strategies for upgrading analyte detection in immuno-PCR studied on identification of type A botulinum neurotoxin by Ryabko, A. K., Kozyr’, A. V., Kolesnikov, A. V., Khlyntseva, A. E., Zharnikova, I. V., Shemyakin, I. G.

“…An efficient method of highly sensitive, specific determination of botulinic type A neurotoxin (which allows the detection of a toxin in a concentration from 1…”
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