Search Results - "Shemetov, Anton A."
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Natural Photoreceptors as a Source of Fluorescent Proteins, Biosensors, and Optogenetic Tools
Published in Annual review of biochemistry (01-01-2015)“…Genetically encoded optical tools have revolutionized modern biology by allowing detection and control of biological processes with exceptional spatiotemporal…”
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A set of monomeric near-infrared fluorescent proteins for multicolor imaging across scales
Published in Nature communications (13-01-2020)“…Bright monomeric near-infrared (NIR) fluorescent proteins (FPs) are in high demand as protein tags for multicolor microscopy and in vivo imaging. Here we apply…”
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3
Smallest near-infrared fluorescent protein evolved from cyanobacteriochrome as versatile tag for spectral multiplexing
Published in Nature communications (17-01-2019)“…From a single domain of cyanobacteriochrome (CBCR) we developed a near-infrared (NIR) fluorescent protein (FP), termed miRFP670nano, with excitation at 645 nm…”
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4
Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo
Published in Nature communications (16-07-2018)“…Photoacoustic (PA) computed tomography (PACT) benefits from genetically encoded probes with photochromic behavior, which dramatically increase detection…”
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How to Increase Brightness of Near-Infrared Fluorescent Proteins in Mammalian Cells
Published in Cell chemical biology (22-06-2017)“…Numerous near-infrared (NIR) fluorescent proteins (FPs) were recently engineered from bacterial photoreceptors but lack of their systematic comparison makes…”
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Neurotrophin receptor tyrosine kinases regulated with near-infrared light
Published in Nature communications (08-03-2019)“…Optical control over the activity of receptor tyrosine kinases (RTKs) provides an efficient way to reversibly and non-invasively map their functions. We…”
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Biochemical characterization of small heat shock protein HspB8 (Hsp22)–Bag3 interaction
Published in Archives of biochemistry and biophysics (01-09-2011)“…[Display omitted] ► Interaction of Bag3 with HspB6 and HspB8 was analyzed by biochemical methods. ► Bag3 tightly interacts with HspB8 forming complexes of…”
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Molecular Interaction of Proteins and Peptides with Nanoparticles
Published in ACS nano (26-06-2012)“…The interaction of proteins in living cells is one of the key processes in the maintenance of their homeostasis. Introduction of additional agents into the…”
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A bacterial phytochrome-based optogenetic system controllable with near-infrared light
Published in Nature methods (01-07-2016)“…Optogenetic tools such as a BphP1–PpsR2 pair can be harnessed to exert spatiotemporal control over signaling pathways or transcriptional events. The…”
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Structure, properties, and functions of the human small heat-shock protein HSP22 (HspB8, H11, E2IG1): A critical review
Published in Journal of neuroscience research (01-02-2008)“…The recently described human HSP22 belongs to the superfamily of small heat‐shock proteins containing a conservative α‐crystallin domain. HSP22 seems to be…”
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A near-infrared genetically encoded calcium indicator for in vivo imaging
Published in Nature biotechnology (01-03-2021)“…While calcium imaging has become a mainstay of modern neuroscience, the spectral properties of current fluorescent calcium indicators limit deep-tissue imaging…”
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Microfluidic System for In-Flow Reversible Photoswitching of Near-Infrared Fluorescent Proteins
Published in Analytical chemistry (Washington) (06-12-2016)“…We have developed a microfluidic flow cytometry system to screen reversibly photoswitchable fluorescent proteins for contrast and stability of reversible…”
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Focusing light inside live tissue using reversibly switchable bacterial phytochrome as a genetically encoded photochromic guide star
Published in Science advances (01-12-2019)“…Focusing light deep by engineering wavefronts toward guide stars inside scattering media has potential biomedical applications in imaging, manipulation,…”
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Obatoclax kills anaplastic thyroid cancer cells by inducing lysosome neutralization and necrosis
Published in Oncotarget (07-06-2016)“…Poorly differentiated and anaplastic thyroid carcinomas are very aggressive, almost invariably lethal neoplasms for which no effective treatment exists. These…”
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Phosphorylation of human small heat shock protein HspB8 (Hsp22) by ERK1 protein kinase
Published in Molecular and cellular biochemistry (01-09-2011)“…A number of phosphomimicking mutants (replacement of Ser/Thr residues by Asp) of human small heat shock protein HspB8 were obtained and phosphorylation of the…”
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Expression, purification and some properties of fluorescent chimeras of human small heat shock proteins
Published in Protein expression and purification (01-03-2012)“…[Display omitted] ► Eight fluorescent chimeras of human small heat shock proteins (sHsp) were obtained. ► Spectral properties of fluorescent proteins (FP) were…”
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An optogenetic system based on bacterial phytochrome controllable with near-infrared light
Published in Nature methods (09-05-2016)“…Light-mediated control of protein-protein interactions to regulate metabolic pathways is an important approach of optogenetics. Here, we report the first…”
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