Search Results - "Shemet, Andrej"

Total Synthesis of (−)-Rhazinilam and Formal Synthesis of (+)-Eburenine and (+)-Aspidospermidine: Asymmetric Cu-Catalyzed Propargylic Substitution by Shemet, Andrej, Carreira, Erick M

“…A total synthesis of (−)-rhazinilam and formal syntheses of (+)-eburenine and (+)-aspidospermidine that rely on a copper­(I)-catalyzed asymmetric propargylic…”
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Pyridyl Radical Cation for C−H Amination of Arenes by Rössler, Simon L., Jelier, Benson J., Tripet, Pascal F., Shemet, Andrej, Jeschke, Gunnar, Togni, Antonio, Carreira, Erick M.

“…Electron‐transfer photocatalysis provides access to the elusive and unprecedented N‐pyridyl radical cation from selected N‐substituted pyridinium reagents. The…”
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Stereochemical Studies of the Opening of Chloro Vinyl Epoxides: Cyclic Chloronium Ions as Intermediates by Shemet, Andrej, Sarlah, David, Carreira, Erick M

“…A systematic study of the opening of a collection of chlorinated vinyl epoxides is reported, which includes experiments that implicate both five- and…”
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Optical Control of Phosphatidic Acid Signaling by Tei, Reika, Morstein, Johannes, Shemet, Andrej, Trauner, Dirk, Baskin, Jeremy M

“…Phosphatidic acids (PAs) are glycerophospholipids that regulate key cell signaling pathways governing cell growth and proliferation, including the mTOR and…”
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Structure-function relationships of HDL in diabetes and coronary heart disease by Cardner, Mathias, Yalcinkaya, Mustafa, Goetze, Sandra, Luca, Edlira, Balaz, Miroslav, Hunjadi, Monika, Hartung, Johannes, Shemet, Andrej, Kränkel, Nicolle, Radosavljevic, Silvija, Keel, Michaela, Othman, Alaa, Karsai, Gergely, Hornemann, Thorsten, Claassen, Manfred, Liebisch, Gerhard, Carreira, Erick, Ritsch, Andreas, Landmesser, Ulf, Krützfeldt, Jan, Wolfrum, Christian, Wollscheid, Bernd, Beerenwinkel, Niko, Rohrer, Lucia, von Eckardstein, Arnold

“…High-density lipoproteins (HDL) contain hundreds of lipid species and proteins and exert many potentially vasoprotective and antidiabetogenic activities on…”
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Assembling the carbon skeleton of A-74528 by Maier, Martin S, Shemet, Andrej, Trauner, Dirk

“…The 2′-phosphodiesterase inhibitor A-74528, which combines an intriguing biosynthesis with unusual biological activity, is one of the most complex type II…”
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Optimized Photoactivatable Lipid Nanoparticles Enable Red Light Triggered Drug Release by Chander, Nisha, Morstein, Johannes, Bolten, Jan S., Shemet, Andrej, Cullis, Pieter R., Trauner, Dirk, Witzigmann, Dominik

“…Encapsulation of small molecule drugs in long‐circulating lipid nanoparticles (LNPs) can reduce toxic side effects and enhance accumulation at tumor sites. A…”
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Optical Control of Mitosis with a Photoswitchable Eg5 Inhibitor by Impastato, Anna C., Shemet, Andrej, Vepřek, Nynke A., Saper, Gadiel, Hess, Henry, Rao, Lu, Gennerich, Arne, Trauner, Dirk

“…Eg5 is a kinesin motor protein that is responsible for bipolar spindle formation and plays a crucial role during mitosis. Loss of Eg5 function leads to the…”
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Optical Control of Lysophosphatidic Acid Signaling by Morstein, Johannes, Dacheux, Mélanie A, Norman, Derek D, Shemet, Andrej, Donthamsetti, Prashant C, Citir, Mevlut, Frank, James A, Schultz, Carsten, Isacoff, Ehud Y, Parrill, Abby L, Tigyi, Gabor J, Trauner, Dirk

“…Lysophosphatidic acid (LPA) is a phospholipid that acts as an extracellular signaling molecule and activates the family of lysophosphatidic acid receptors (LPA…”
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Synthesis and Structure–Activity Relationship Studies of Anti-Inflammatory Epoxyisoprostane Analogues by Wolleb, Helene, Ogawa, Seiji, Schneider, Michael, Shemet, Andrej, Muri, Jonathan, Kopf, Manfred, Carreira, Erick M

“…The lactone derivative of the epoxyisoprostane EC is a highly effective inhibitor of the secretion of the proinflammatory cytokine IL-6. Herein, a modular…”
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Bi(OTf)3-catalyzed three-component synthesis of α-amino acid derivatives by Schneider, Angelika E, Beisel, Tamara, Shemet, Andrej, Manolikakes, Georg

“…A highly efficient Bi(OTf)3-catalyzed multicomponent synthesis of arylglycines from readily available starting materials is described. The reaction proceeds…”
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Optical Control of Mitosis with a Photoswitchable Eg5 Inhibitor by Impastato, Anna C., Shemet, Andrej, Vepřek, Nynke A., Saper, Gadiel, Hess, Henry, Rao, Lu, Gennerich, Arne, Trauner, Dirk

“…Eg5 is a kinesin motor protein that is responsible for bipolar spindle formation and plays a crucial role during mitosis. Loss of Eg5 function leads to the…”
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Pyridyl Radical Cation for C−H Amination of Arenes by Rössler, Simon L., Jelier, Benson J., Tripet, Pascal F., Shemet, Andrej, Jeschke, Gunnar, Togni, Antonio, Carreira, Erick M.

“…Electron‐transfer photocatalysis provides access to the elusive and unprecedented N‐pyridyl radical cation from selected N‐substituted pyridinium reagents. The…”
Get full text