Search Results - "Shelyakin, Pavel V"
-
1
Genome-wide analysis of cell type-specific gene transcription during spore formation in Clostridium difficile
Published in PLoS genetics (01-10-2013)“…Clostridium difficile, a Gram positive, anaerobic, spore-forming bacterium is an emergent pathogen and the most common cause of nosocomial diarrhea. Although…”
Get full text
Journal Article -
2
Chlamydia pan-genomic analysis reveals balance between host adaptation and selective pressure to genome reduction
Published in BMC genomics (12-09-2019)“…Chlamydia are ancient intracellular pathogens with reduced, though strikingly conserved genome. Despite their parasitic lifestyle and isolated intracellular…”
Get full text
Journal Article -
3
Genome-Wide Transcription Start Site Mapping and Promoter Assignments to a Sigma Factor in the Human Enteropathogen Clostridioides difficile
Published in Frontiers in microbiology (13-08-2020)“…The emerging human enteropathogen Clostridioides difficile is the main cause of diarrhea associated with antibiotherapy. Regulatory pathways underlying the…”
Get full text
Journal Article -
4
Micro-evolution of three Streptococcus species: selection, antigenic variation, and horizontal gene inflow
Published in BMC evolutionary biology (27-03-2019)“…The genus Streptococcus comprises pathogens that strongly influence the health of humans and animals. Genome sequencing of multiple Streptococcus strains…”
Get full text
Journal Article -
5
HLA-DR Expression in Natural Killer Cells Marks Distinct Functional States, Depending on Cell Differentiation Stage
Published in International journal of molecular sciences (01-05-2024)“…HLA-DR-positive NK cells, found in both healthy individuals and patients with different inflammatory diseases, are characterized as activated cells. However,…”
Get full text
Journal Article -
6
Aberrant adaptive immune response underlies genetic susceptibility to tuberculosis
Published in Frontiers in immunology (2024)“…( ) remains a major threat worldwide, although only a fraction of infected individuals develops tuberculosis (TB). TB susceptibility is shaped by multiple…”
Get full text
Journal Article -
7
Functionally specialized human CD4 + T-cell subsets express physicochemically distinct TCRs
Published in eLife (08-12-2020)“…The organizational integrity of the adaptive immune system is determined by functionally discrete subsets of CD4 T cells, but it has remained unclear to what…”
Get full text
Journal Article -
8
Microbiomes of gall-inducing copepod crustaceans from the corals Stylophora pistillata (Scleractinia) and Gorgonia ventalina (Alcyonacea)
Published in Scientific reports (01-08-2018)“…Corals harbor complex and diverse microbial communities that strongly impact host fitness and resistance to diseases, but these microbes themselves can be…”
Get full text
Journal Article -
9
The Influence of Kerosene on Microbiomes of Diverse Soils
Published in Life (Basel, Switzerland) (31-01-2022)“…One of the most important challenges for soil science is to determine the limits for the sustainable functioning of contaminated ecosystems. The response of…”
Get full text
Journal Article -
10
Naïve Regulatory T Cell Subset Is Altered in X-Linked Agammaglobulinemia
Published in Frontiers in immunology (19-08-2021)“…The interplay between T- and B-cell compartments during naïve, effector and memory T cell maturation is critical for a balanced immune response. Primary B-cell…”
Get full text
Journal Article -
11
Data on the temporal changes in soil properties and microbiome composition after a jet-fuel contamination during the pot and field experiments
Published in Data in brief (01-02-2023)“…The soil response to a jet-fuel contamination is uncertain. In this article, original data on the influence of a jet-fuel spillage on the topsoil properties…”
Get full text
Journal Article -
12
Monitoring of meat quality and change-point detection by a sensor array and profiling of bacterial communities
Published in Analytica chimica acta (01-09-2024)“…Real-time monitoring of food consumer quality remains challenging due to diverse bio-chemical processes taking place in the food matrices, and hence it…”
Get full text
Journal Article -
13
MHC-II alleles shape the CDR3 repertoires of conventional and regulatory naïve CD4⁺ T cells
Published in Proceedings of the National Academy of Sciences - PNAS (16-06-2020)“…T cell maturation and activation depend upon T cell receptor (TCR) interactions with a wide variety of antigenic peptides displayed in a given major…”
Get full text
Journal Article -
14
Accounting for B-cell Behavior and Sampling Bias Predicts Anti-PD-L1 Response in Bladder Cancer
Published in Cancer immunology research (01-03-2022)“…Cancer immunotherapy is predominantly based on T cell-centric approaches. At the same time, the adaptive immune response in the tumor environment also includes…”
Get more information
Journal Article -
15
Functionally specialized human CD4.sup.+ T-cell subsets express physicochemically distinct TCRs
Published in eLife (08-12-2020)“…The organizational integrity of the adaptive immune system is determined by functionally discrete subsets of CD4.sup.+ T cells, but it has remained unclear to…”
Get full text
Journal Article -
16
Genome-Wide Analysis of Cell Type-Specific Gene Transcription during Spore Formation in Clostridium difficile: e1003756
Published in PLoS genetics (01-10-2013)“…Clostridium difficile, a Gram positive, anaerobic, spore-forming bacterium is an emergent pathogen and the most common cause of nosocomial diarrhea. Although…”
Get full text
Journal Article