Search Results - "Shelling, A N"

Zebrafish as a model for long QT syndrome: the evidence and the means of manipulating zebrafish gene expression by Leong, I.U.S, Skinner, J.R, Shelling, A.N, Love, D.R

“…Congenital long QT syndrome (LQT) is a group of cardiac disorders associated with the dysfunction of cardiac ion channels. It is characterized by prolongation…”
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Sex of Bovine Embryos May Be Related to Mothers' Preovulatory Follicular Testosterone by Grant, V.J, Irwin, R.J, Standley, N.T, Shelling, A.N, Chamley, L.W

“…Although the sex of the offspring in mammals is commonly viewed as a matter of chance (depending on whether an X or a Y chromosome-bearing spermatozoon reaches…”
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Inhibin and premature ovarian failure by Chand, A.L., Harrison, C.A., Shelling, A.N.

“…BACKGROUND Elucidation of the causes of premature ovarian failure (POF) is difficult due to the heterogeneity of the condition. Inhibin is a potential…”
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Ovarian reserve tests for predicting fertility outcomes for assisted reproductive technology: the International Systematic Collaboration of Ovarian Reserve Evaluation protocol for a systematic review of ovarian reserve test accuracy by Johnson, NP, Bagrie, EM, Coomarasamy, A, Bhattacharya, S, Shelling, AN, Jessop, S, Farquhar, C, Khan, KS

“…Background  The presence of a wide range of tests of ovarian reserve suggests that no single test provides a sufficiently accurate result. Many tests are used…”
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Identification of novel mutations in FOXL2 associated with premature ovarian failure by Harris, S.E., Chand, A.L., Winship, I.M., Gersak, K., Aittomäki, K., Shelling, A.N.

“…Premature ovarian failure (POF) affects ∼1% of women and is known to be caused by sex chromosome abnormalities, iatrogenic agents and autoimmune diseases, but…”
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Genetic markers of repolarization and arrhythmic events after acute coronary syndromes by Earle, N.J., BSc (Hons), Poppe, K.K., PhD, Pilbrow, A.P., PhD, Cameron, V.A., PhD, FAHA, Troughton, R.W., MBChB, PhD, Skinner, J.R., FRACP, MD, Love, D.R., PhD, Shelling, A.N., PhD, Whalley, G.A., PhD, Ellis, C.J., BM, Richards, A.M., MD, DSc, FRCP, FRACP, FAHA, Doughty, R.N., MD, FRCP, FRACP, FESC

“…Background There is a genetic contribution to the risk of ventricular arrhythmias in survivors of acute coronary syndromes (ACS). We wished to explore the role…”
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FOXL2 copy number changes in the molecular pathogenesis of BPES: unique cohort of 17 deletions by D'haene, B, Nevado, J, Pugeat, M, Pierquin, G, Lowry, R.B, Reardon, W, Delicado, A, García-Miñaur, S, Palomares, M, Courtens, W, Stefanova, M, Wallace, S, Watkins, W, Shelling, A.N, Wieczorek, D, Veitia, R.A, De Paepe, A, Lapunzina, P, De Baere, E

“…Blepharophimosis Syndrome (BPES) is an autosomal dominant developmental disorder of the eyelids with or without ovarian dysfunction caused by FOXL2 mutations…”
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Investigation of the role of transforming growth factor beta in the development and progression of granulosa cell tumours of the ovary by Muthukaruppan, A., Arora, S.K., Blenkiron, C., Shelling, A.N.

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Blepharophimosis and bilateral Duane syndrome associated with a FOXL2 mutation by Vincent, AL, Watkins, WJ, Sloan, BH, Shelling, AN

“…This case describes the novel coexistence of sporadic blepharophimosis–ptosis–epicanthus inversus syndrome (BPES) and bilateral type I Duane syndrome in a…”
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The genetic analysis of ovarian cancer by SHELLING, A. N, COOKE, I. E, GANESAN, T. S

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Epigenetic regulation of inhibin alpha-subunit gene in prostate cancer cell lines by Balanathan, P, Ball, EM, Wang, H, Harris, SE, Shelling, AN, Risbridger, GP

“…Inhibin was first identified as a gonad-derived regulator of pituitary FSH; however, it has subsequently been shown to be a tumour suppressor in the gonad and…”
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Analysis of the TGFβ functional pathway in epithelial ovarian carcinoma by FRANCIS-THICKPENNY, K. M, RICHARDSON, D. M, VAN EE, C. C, LOVE, D. R, WINSHIP, I. M, BAGULEY, B. C, CHENEVIX-TRENCH, G, SHELLING, A. N

“…Epithelial ovarian carcinoma is often diagnosed at an advanced stage of disease and is the leading cause of death from gynaecological neoplasia. The genetic…”
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SPRASA, a novel sperm protein involved in immune‐mediated infertility by Chiu, W.W.C., Erikson, E.K.L., Sole, C.A., Shelling, A.N., Chamley, L.W.

“…BACKGROUND: Antisperm antibodies (ASA) may be an important cause of infertility, but current tests for the detection of ASA have poor prognostic value…”
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Role of p53 in drug resistance in ovarian cancer by Shelling, A N

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The Lipiodol Uterine Bathing Effect to Improve Fertility May Include Uterine Natural Killer Cell Up-regulation in the Endometrium by Johnson, N. P., Baidya, S., Jessup, S. O., Muthukaruppan, A., Hadden, W. E., Hull, M. L., Mehta, S., Shelling, A. N., Print, C. G., Chamley, L. W.

“…BACKGROUND: Lipiodol has a dramatic short term fertility enhancing effect for women with endometriosis. Microarray studies have shown transcriptomic regulation…”
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Array comparative genomic hybridization for the detection of submicroscopic copy number variations of the X chromosome in women with premature ovarian failure by Dudding, T.E., Lawrence, O., Winship, I., Froyen, G., Vandewalle, J., Scott, R., Shelling, A.N.

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Posthumous diagnosis of long QT syndrome from neonatal screening cards by Gladding, P.A., MBCHB, Evans, C.-A., MSc (Med), Crawford, J., NZCS, Chung, S.K., BSc (Hons), Vaughan, A., BMLS, Webster, D., PhD, Neas, K., FRACP, Love, D.R., PhD, Rees, M.I., PhD, Shelling, A.N., PhD, Skinner, J.R., MD

“…Background Molecular autopsy in sudden unexplained death in the young (SUDY) victims cannot usually be performed if tissue suitable for DNA extraction is not…”
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Activity, synthesis, storage, and messenger RNA of cyclooxygenase in intrauterine tissues of guinea pigs near term and during labor by SCHELLENBERG, J.-C, SHELLING, A. N, VAN EE, C. C

“…Whether the reported gestation-dependent increase in cyclooxygenase activity in gestational tissues is due to an accumulation of cyclooxygenase in vivo or an…”
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Molecular genetics of ovarian cancer by SHELLING, Andrew N, FOULKES, William

“…This is a review of the approaches that can be used to analyze genetic changes in ovarian cancer. Traditional gene localization methods are discussed, followed…”
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Localization of an epithelial-specific receptor kinase (EDDR1) to chromosome 6q16 by Shelling, A.N., Butler, R., Jones, T., Laval, S., Boyle, J.M., Ganesan, T.S.

“…A protein receptor tyrosine kinase (EDDR1) has been isolated from a complementary DNA library of SKOV-3, an epithelial ovarian cancer cell line. The primary…”
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