Search Results - "Sheller, J R"

Assessment of oxidant stress in allergic asthma by measurement of the major urinary metabolite of F2-isoprostane, 15-F2t-IsoP (8-iso-PGF2α) by Dworski, R., Jackson Roberts Ii, L., Murray, J. J., Morrow, J. D., Hartert, T. V., Sheller, J. R.

“…Asthma is a chronic inflammatory disease of the airways which may involve an oxidant injury to the lung. Assessment of oxidant stress is difficult in vivo, but…”
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5-Lipoxygenase products are necessary for ovalbumin-induced airway responsiveness in mice by Irvin, C G, Tu, Y P, Sheller, J R, Funk, C D

“…To determine the role of 5-lipoxygenase products in the development of airway reactivity that follows antigen exposure, we sensitized mice by intraperitoneal…”
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Effect of oral prednisone on airway inflammatory mediators in atopic asthma by Dworski, R, Fitzgerald, G A, Oates, J A, Sheller, J R

“…The mechanism of steroid action in asthma is unknown. Because steroids have effects in vitro on eicosanoid synthesis, we determined the effect of oral…”
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Suppression of airway hyperresponsiveness induced by ovalbumin sensitisation and RSV infection with Y-27632, a Rho kinase inhibitor by Hashimoto, K, Peebles, R S, Sheller, J R, Jarzecka, K, Furlong, J, Mitchell, D B, Hartert, T V, Graham, B S

“…Background: Smooth muscle contraction is one of the hallmarks of asthma. A recently developed pyridine derivative, Y-27632, a selective Rho kinase inhibitor,…”
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Eicosanoids in bronchoalveolar lavage fluid of aspirin-intolerant patients with asthma after aspirin challenge by Sladek, K, Dworski, R, Soja, J, Sheller, J R, Nizankowska, E, Oates, J A, Szczeklik, A

“…We have recently shown that oral aspirin provocation leads to an increase in LTE4 and a reduction in 11-dehydro-TXB2 levels in urine of patients with aspirin…”
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Induced sputum eicosanoid concentrations in asthma by PAVORD, I. D, WARD, R, WOLTMANN, G, WARDLAW, A. J, SHELLER, J. R, DWORSKI, R

“…Further definition of the role of leukotrienes (LT) and prostaglandins (PG) in asthma would be helped by a noninvasive method for assessing airway production…”
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Inhibition of Eicosanoid Biosynthesis by Glucocorticoids in Humans by Sebaldt, Rolf J., Sheller, James R., Oates, John A., Roberts, L. Jackson, FitzGerald, Garret A.

“…Therapeutic doses of glucocorticoids are thought to inhibit prostaglandin and leukotriene formation in humans. Several studies in animals, however, have failed…”
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Salmeterol prevents aspirin-induced attacks of asthma and interferes with eicosanoid metabolism by SZCZEKLIK, A, DWORSKI, R, MASTALERZ, L, PROKOP, A, SHELLER, J. R, NIZANKOWSKA, E, CMIEL, A, OATES, J. A

“…We determined the effect of a long acting beta2-agonist, salmeterol, on aspirin-induced asthma (AIA) attacks and urinary release of eicosanoids in a…”
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Induced sputum inflammatory mediator concentrations in eosinophilic bronchitis and asthma by BRIGHTLING, Christopher E, WARD, Richard, WOLTMANN, Gerrit, BRADDING, Peter, SHELLER, James R, DWORSKI, Ryszard, PAVORD, Ian D

“…Eosinophilic bronchitis is a common cause of chronic cough, which like asthma is characterized by sputum eosinophilia, but in contrast to asthma there is no…”
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Ethnic differences in response to morphine by Zhou, H H, Sheller, J R, Nu, H, Wood, M, Wood, A J

“…Only recently has attention been focused on the importance of interethnic differences as determinants of interindividual variability in drug response. We…”
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EP2 receptor mediates bronchodilation by PGE2 in mice by Sheller, J. R, Mitchell, Daphne, Meyrick, Barbara, Oates, John, Breyer, Richard

“…Departments of 1  Medicine and 2  Pathology, Vanderbilt University Medical Center, Nashville, Tennessee 37232 PGE 2 is an important cyclooxygenase product that…”
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Prostaglandin E2 Decreases Allergen-stimulated Release of Prostaglandin D2 in Airways of Subjects with Asthma by HARTERT, TINA V, DWORSKI, RYSZARD T, MELLEN, BEVERLY G, OATES, JOHN A, MURRAY, JOHN J, SHELLER, JAMES R

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Prematurity is associated with abnormal airway function in childhood by Galdès-Sebaldt, M, Sheller, J R, Grogaard, J, Stahlman, M

“…To evaluate the long-term effect of prematurity and/or hyaline membrane disease (HMD) on pulmonary function and airway reactivity, we studied 49 prematurely…”
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The Shanghai Women's Asthma and Allergy Study: Objectives, Design, and Recruitment Results by Hartert, Tina V., Deng, Xinqing, Hartman, Terryl J., Wen, Wanqing, Yang, Gong, Gao, Yu-Tang, Jin, Meiling, Bai, Chunxue, Gross, Myron, Roberts, L. Jackson, Sheller, James R., Christman, John, Dupont, William, Griffin, Marie, Shu, Xiao Ou

“…The Shanghai Women's Asthma and Allergy Study is the first population-based incidence study designed to assess the associations of dietary antioxidant intake…”
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Respiratory syncytial virus infection prolongs methacholine-induced airway hyperresponsiveness in ovalbumin-sensitized mice by Peebles Jr, R. Stokes, Sheller, James R., Johnson, Joyce E., Mitchell, Daphne B., Graham, Barney S.

“…Severe respiratory syncytial virus (RSV)‐induced disease is associated with childhood asthma and atopy. We combined models of allergen sensitization and RSV…”
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Inhaled steroids in asthma by Aronica, M, Sheller, J R

“…Inhaled steroids are the mainstay of anti-inflammatory treatment of asthma. Topical application of steroids to the asthmatic airway has many benefits as well…”
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Cyclooxygenase Inhibition Increases Interleukin 5 and Interleukin 13 Production and Airway Hyperresponsiveness in Allergic Mice by STOKES PEEBLES, R., Jr, DWORSKI, RYSZARD, COLLINS, ROBERT D, JARZECKA, KASIA, MITCHELL, DAPHNE B, GRAHAM, BARNEY S, SHELLER, JAMES R

“…The immunomodulatory role of arachidonic acid metabolites in allergic sensitization is undefined. Prostaglandin E(2) (PGE(2)), a product of arachidonic acid…”
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Regional distribution of protease-resistant prion protein in fatal familial insomnia by Parchi, P, Castellani, R, Cortelli, P, Montagna, P, Chen, S G, Petersen, R B, Manetto, V, Vnencak-Jones, C L, McLean, M J, Sheller, J R

“…Protease-resistant prion protein, total prion protein, and glial fibrillary acidic protein were measured in various brain regions from 9 subjects with fatal…”
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Use of pulse oximetry to recognize severity of airflow obstruction in obstructive airway disease: correlation with pulsus paradoxus by Hartert, T V, Wheeler, A P, Sheller, J R

“…The purpose of this cross-sectional study was to confirm the observation that pulse oximetry tracing correlates with pulsus paradoxus, and is therefore a…”
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Viral infections in asthma by Peebles, Jr, R S, Hartert, T V, Sheller, J R

“…This article summarizes recent findings regarding the impact of viruses on reactive airway disease. Technical breakthroughs are improving our ability to…”
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