Search Results - "Shelke, Namdev"

Bioactive polymeric scaffolds for tissue engineering by Stratton, Scott, Shelke, Namdev B., Hoshino, Kazunori, Rudraiah, Swetha, Kumbar, Sangamesh G.

“…A variety of engineered scaffolds have been created for tissue engineering using polymers, ceramics and their composites. Biomimicry has been adopted for…”
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Polysaccharide biomaterials for drug delivery and regenerative engineering by Shelke, Namdev B., James, Roshan, Laurencin, Cato T., Kumbar, Sangamesh G.

“…Polymers derived from plant (polysaccharides) and animal (proteins) kingdoms have been widely used for a variety of biomedical applications including drug…”
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Engineering a segmented dual-reservoir polyurethane intravaginal ring for simultaneous prevention of HIV transmission and unwanted pregnancy by Clark, Justin T, Clark, Meredith R, Shelke, Namdev B, Johnson, Todd J, Smith, Eric M, Andreasen, Andrew K, Nebeker, Joel S, Fabian, Judit, Friend, David R, Kiser, Patrick F

“…The HIV/AIDS pandemic and its impact on women prompt the investigation of prevention strategies to interrupt sexual transmission of HIV. Long-acting drug…”
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Bioactive polymeric nanofiber matrices for skin regeneration by Guadalupe, Eross, Ramos, Daisy, Shelke, Namdev B., James, Roshan, Gibney, Christian, Kumbar, Sangamesh G.

“…ABSTRACT Electrospun nanofiber matrices have attracted a great deal of attention as matrices for skin repair and regeneration. The current manuscript reports…”
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Peripheral Nerve Regeneration Strategies: Electrically Stimulating Polymer Based Nerve Growth Conduits by Anderson, Matthew, Shelke, Namdev B, Manoukian, Ohan S, Yu, Xiaojun, McCullough, Louise D, Kumbar, Sangamesh G

“…Treatment of large peripheral nerve damages ranges from the use of an autologous nerve graft to a synthetic nerve growth conduit. Biological grafts, in spite…”
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Influence of chondroitin sulfate and hyaluronic acid presence in nanofibers and its alignment on the bone marrow stromal cells: cartilage regeneration by Lee, Paul, Tran, Katelyn, Chang, Wei, Shelke, Namdev B, Kumbar, Sangamesh G, Yu, Xiaojun

“…Cartilage degeneration is the major cause of disability and poses several challenges to repair and regenerate. Conventional surgical treatments often induce…”
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Novel interpenetrating polymer network microspheres of chitosan and methylcellulose for controlled release of theophylline by Rokhade, Ajit P., Shelke, Namdev B., Patil, Sangamesh A., Aminabhavi, Tejraj M.

“…Interpenetrating polymer network (IPN) microspheres of chitosan (CS) and methylcellulose (MC) were prepared by emulsion-crosslinking in the presence of…”
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A smart methodology to fabricate electrospun chitosan nanofiber matrices for regenerative engineering applications by Nada, Ahmed A., James, Roshan, Shelke, Namdev B., Harmon, Matthew D., Awad, Hassan M., Nagarale, Rajaram K., Kumbar, Sangamesh G.

“…The electrospinning of chitosan remains challenging due to its rigid crystalline structure, insufficient viscosity, and limited solubility in common organic…”
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Neural tissue engineering: nanofiber-hydrogel based composite scaffolds by Shelke, Namdev B., Lee, Paul, Anderson, Matthew, Mistry, Nikhil, Nagarale, Rajaram K., Ma, Xin-Ming, Yu, Xiaojun, Kumbar, Sangamesh G.

“…Scaffolds used for soft tissue regeneration are designed to mimic the native extracellular matrix (ECM) structurally and provide adequate mechanical strength…”
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Guided differentiation of bone marrow stromal cells on co-cultured cartilage and bone scaffolds by Lee, Paul, Tran, Katelyn, Zhou, Gan, Bedi, Asheesh, Shelke, Namdev B, Yu, Xiaojun, Kumbar, Sangamesh G

“…Focal chondral defects that result from traumatic injuries to the knee remain one of the most common causes of disability in patients. Current solutions for…”
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Formulation and in-vitro evaluation of novel starch-based tableted microspheres for controlled release of ampicillin by Mundargi, Raghavendra C., Shelke, Namdev B., Rokhade, Ajit P., Patil, Sangamesh A., Aminabhavi, Tejraj M.

“…This study reports the preparation of starch-based tableted microspheres that are crosslinked with epichlorohydrin (EPI) using a modified water-in-oil (w/o)…”
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Delivery of SAR 1118 to the retina via ophthalmic drops and its effectiveness in a rat streptozotocin (STZ) model of diabetic retinopathy (DR) by Rao, Vidhya R, Prescott, Elizabeth, Shelke, Namdev B, Trivedi, Ruchit, Thomas, Peter, Struble, Craig, Gadek, Tom, O'Neill, Charles A, Kompella, Uday B

“…To determine the pharmacokinetics of SAR 1118, a small-molecule antagonist of leukocyte function-associated antigen (LFA)-1, after administration of ophthalmic…”
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Synthesis and characterization of poly(caprolactone triol succinate) elastomer for tissue engineering application by Harmon, Matthew D., James, Roshan, Shelke, Namdev B., Kumbar, Sangamesh G.

“…ABSTRACT A novel polymer poly(caprolactone triol succinate) (PPCLSu) was synthesized from monomers polycaprolactone triol and succinic acid by direct…”
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Bioactive polymeric scaffolds for osteochondral tissue engineering: in vitro evaluation of the effect of culture media on bone marrow stromal cells by Lee, Paul, Tran, Katelyn, Chang, Wei, Fang, Ya-Lin, Zhou, Gan, Junka, Radoslaw, Shelke, Namdev B., Yu, Xiaojun, Kumbar, Sangamesh G.

“…The goal of this study was to determine the efficacy of the bioactive scaffold system to initiate bone marrow stromal cell (BMSC) differentiation into…”
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Novel thermo-responsive semi-interpenetrating network microspheres of gellan gum-poly(N-isopropylacrylamide) for controlled release of atenolol by Mundargi, Raghavendra C, Shelke, Namdev B, Babu, V. Ramesh, Patel, Pradip, Rangaswamy, Vidhya, Aminabhavi, Tejraj M

“…Thermoresponsive microspheres of gellan gum-poly(N-isopropylacrylamide), i.e., GG-P(NIPAAm) semi-interpenetrating polymer networks (semi-IPNs) have been…”
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Synthesis and characterization of novel poly(sebacic anhydride- co-Pluronic F68/F127) biopolymeric microspheres for the controlled release of nifedipine by Shelke, Namdev B., Aminabhavi, Tejraj M.

“…Amphiphilic block copolymers composed of prepoly(sebacic anhydride) and Pluronic-F68/F127 have been synthesized in different molar compositions via…”
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Novel hydrogel microspheres of chitosan and pluronic F-127 for controlled release of 5-fluorouracil by Rokhade, Ajit P., Shelke, Namdev B., Patil, Sangamesh A., Aminabhavi, Tejraj M.

“…Hydrogel microspheres of chitosan (CS) and Pluronic F127 (PF-127) were prepared by the emulsion-crosslinking method employing glutaraldehyde (GA) as a…”
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Gelatin Nanofiber Matrices Derived from Schiff Base Derivative for Tissue Engineering Applications by Jaiswal, Devina, James, Roshan, Shelke, Namdev B, Harmon, Matthew D, Brown, Justin L, Hussain, Fazle, Kumbar, Sangamesh G

“…Electrospinning of water-soluble polymers and retaining their mechanical strength and bioactivity remain challenging. Volatile organic solvent soluble polymers…”
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Preparation and evaluation of novel blend microspheres of poly(lactic-co-glycolic)acid and pluronic F68/127 for controlled release of repaglinide by Shelke, Namdev B, Rokhade, Ajit P, Aminabhavi, Tejraj M

“…The objective of the present work was to study the release behavior of plain and blend microspheres (MS) of PLGA and Pluronic F68/127. In this study, a novel…”
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Intravitreal poly(l-lactide) microparticles sustain retinal and choroidal delivery of TG-0054, a hydrophilic drug intended for neovascular diseases by Shelke, Namdev B., Kadam, Rajendra, Tyagi, Puneet, Rao, Vidhya R., Kompella, Uday B.

“…While poorly soluble drugs such as corticosteroids sustain drug delivery in the vitreous humor by virtue of slow dissolution, macromolecules such as antibodies…”
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