Search Results - "Shelar, Patrick B."

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  1. 1

    Human neural crest induction by temporal modulation of WNT activation by Gomez, Gustavo A., Prasad, Maneeshi S., Sandhu, Nabjot, Shelar, Patrick B., Leung, Alan W., García-Castro, Martín I.

    Published in Developmental biology (15-05-2019)
    “…The developmental biology of neural crest cells in humans remains unexplored due to technical and ethical challenges. The use of pluripotent stem cells to…”
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    Journal Article
  2. 2

    FGF Modulates the Axial Identity of Trunk hPSC-Derived Neural Crest but Not the Cranial-Trunk Decision by Hackland, James O.S., Shelar, Patrick B., Sandhu, Nabjot, Prasad, Maneeshi S., Charney, Rebekah M., Gomez, Gustavo A., Frith, Thomas J.R., García-Castro, Martín I.

    Published in Stem cell reports (14-05-2019)
    “…The neural crest is a transient embryonic tissue that gives rise to a multitude of derivatives in an axially restricted manner. An in vitro counterpart to…”
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    Journal Article
  3. 3

    Blastula stage specification of avian neural crest by Prasad, Maneeshi S., Uribe-Querol, Eileen, Marquez, Jonathan, Vadasz, Stephanie, Yardley, Nathan, Shelar, Patrick B., Charney, Rebekah M., García-Castro, Martín I.

    Published in Developmental biology (01-02-2020)
    “…Cell fate specification defines the earliest steps towards a distinct cell lineage. Neural crest, a multipotent stem cell population, is thought to be…”
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    Journal Article
  4. 4

    WNT/β-catenin modulates the axial identity of embryonic stem cell-derived human neural crest by Gomez, Gustavo A, Prasad, Maneeshi S, Wong, Man, Charney, Rebekah M, Shelar, Patrick B, Sandhu, Nabjot, Hackland, James O S, Hernandez, Jacqueline C, Leung, Alan W, García-Castro, Martín I

    Published in Development (Cambridge) (29-08-2019)
    “…WNT/β-catenin signaling is crucial for neural crest (NC) formation, yet the effects of the magnitude of the WNT signal remain ill-defined. Using a robust model…”
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    Journal Article
  5. 5

    WNT/β-CATENIN modulates the axial identity of ES derived human neural crest by Gomez, Gustavo A., Prasad, Maneeshi S., Wong, Man, Charney, Rebekah M., Shelar, Patrick B., Sandhu, Nabjot, Hackland, James O. S., Hernandez, Jacqueline C., Leung, Alan W., García-Castro, Martín I.

    Published in Development (Cambridge) (01-01-2019)
    “…WNT/β-CATENIN signaling is critical for neural crest (NC) formation, yet magnitude effects of the signal remain ill-defined. Using a robust model of human NC…”
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    Journal Article