Search Results - "Shekoohi, Sahar"

Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth by Shekoohi, Sahar, Rajasekaran, Santhanasabapathy, Patel, Dhaval, Yang, Shu, Liu, Wang, Huang, Shile, Yu, Xiuping, Witt, Stephan N.

“…The protein alpha-synuclein (α-syn) is unusual because, depending on its conformation and the type of cell in which it is expressed, it is pro-death or…”
Get full text

Transcriptomic analysis of melanoma cells reveals an association of α-synuclein with regulation of the inflammatory response by Rajasekaran, Santhanasabapathy, Cheng, Siyuan, Gajendran, Nithya, Shekoohi, Sahar, Chesnokova, Liudmila, Yu, Xiuping, Witt, Stephan N.

“…The Parkinson’s disease protein, alpha-synuclein (α-syn/ SNCA ), is highly expressed in neurons and melanomas. The goal of this study was to reveal the…”
Get full text

The impact of health maintenance organizations on improving cardiac surgery outcomes by Skidmore, Kimberly L., Flattmann, Farrah E., Cagle, Hayden, Shekoohi, Sahar, Kaye, Alan D.

“…Background and objectives: California is one of a few states with mandatory reporting of mortality after coronary artery bypass graft (CABG) surgery. The…”
Get full text

The Significance of Equipment Availability and Anesthesia Educational Conferences to Decision-Making for EKG Lead V5 Abnormalities by Skidmore, Kimberly L, Drinkard, Joseph, Randall, Henson M, Varrassi, Giustino, Shekoohi, Sahar, Kaye, Alan D

“…Introduction To predict postoperative myocardial infarction rates in patients who undergo noncardiac surgery, the Canadian Cardiovascular Society Guidelines on…”
Get full text

The Evolving Role of Calcium Channel Blockers in Hypertension Management: Pharmacological and Clinical Considerations by Jones, Kamryn E, Hayden, Shaun L, Meyer, Hannah R, Sandoz, Jillian L, Arata, William H, Dufrene, Kylie, Ballaera, Corrado, Lopez Torres, Yair, Griffin, Patricia, Kaye, Adam M, Shekoohi, Sahar, Kaye, Alan D

“…Worldwide, hypertension is the leading risk factor for cardiovascular disease and death. An estimated 122 million people, per the American Heart Association in…”
Get full text

Left Infrapatellar Branch of the Saphenous Peripheral Nerve Stimulation Relieves Refractory Pain Following Total Knee Replacement by Castine, Abigayle M, Robinson, Christopher L, Fair, Richard N, Varrassi, Giustino, Shekoohi, Sahar, Kaye, Alan D

“…Osteoarthritis, the most common joint disease of adults worldwide, is increasing in prevalence due to an increase in aging and rates of obesity in developed…”
Get full text

Delirium Tremens: A Review of Clinical Studies by Kaye, Alan D, Staser, Amanda N, Mccollins, Tiombee S, Zheng, Jackson, Berry, Fouad A, Burroughs, Caroline R, Heisler, Michael, Mouhaffel, Aya, Ahmadzadeh, Shahab, Kaye, Adam M, Shekoohi, Sahar, Varrassi, Giustino

“…Delirium tremens (DT) is a severe condition resulting from alcohol withdrawal. This review highlights the challenges in diagnosing and managing DT and…”
Get full text

Hyponatremia With Anticonvulsant Medications: A Narrative Review by Bembenick, Kristin Nicole, Mathew, Jibin, Heisler, Michael, Siddaiah, Harish, Moore, Peyton, Robinson, Christopher L, Kaye, Adam M, Shekoohi, Sahar, Kaye, Alan D, Varrassi, Giustino

“…Hyponatremia is an adverse effect of many antiseizure medications (ASMs). It occurs with interference with the normal balance of electrolytes within the body…”
Get full text

Topiramate (Topamax): Evolving Role in Weight Reduction Management: A Narrative Review by Wajid, Irza, Vega, Alexis, Thornhill, Katherine, Jenkins, Jack, Merriman, Chandler, Chandler, Debbie, Shekoohi, Sahar, Cornett, Elyse M, Kaye, Alan D

“…Obesity has emerged as a widespread disease with epidemic proportions, necessitating effective management to enhance the overall health outcomes of patients…”
Get full text

Acromegaly: Pathophysiological Considerations and Treatment Options Including the Evolving Role of Oral Somatostatin Analogs by Daniel, Charles P., Wagner, Maxwell J., Borne, Grant E., Plaisance, Connor J., Ahmadzadeh, Shahab, Aquino, Alfonso, Shekoohi, Sahar, Kaye, Adam M., Cornett, Elyse M., Kaye, Alan D.

“…Acromegaly is a condition most commonly diagnosed in the fifth decade of life and has numerous treatment options. In this regard, Mycapssa® is the first…”
Get full text

Overview of Median Arcuate Ligament Syndrome: A Narrative Review by Upshaw, Will, Richey, John, Ravi, Gurjot, Chen, Adrian, Spillers, Noah J, Ahmadzadeh, Shahab, Varrassi, Giustino, Shekoohi, Sahar, Kaye, Alan D

“…Median arcuate ligament syndrome (MALS) is a rare disorder caused primarily by compression of the celiac trunk by the median arcuate ligament (MAL). This…”
Get full text

Interventional procedures for refractory neuropathic pain by Hannah G. Matejowsky, Saurabh Kataria, Noah J. Spillers, Collyn C. O’Quin, Sonnah Barrie, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D. Kaye

“…Neuropathic pain is an increasingly common disease affecting millions of individuals worldwide. Refractory pain poses a significant impact on patients’ quality…”
Get full text

Valley Fever: Pathogenesis and Evolving Treatment Options by Zaheri, Spencer C, Field, Elizabeth, Orvin, Cody A, Perilloux, Dominique M, Klapper, Rachel J, Shelvan, Anitha, Ahmadzadeh, Shahab, Shekoohi, Sahar, Kaye, Alan D, Varrassi, Giustino

“…Coccidioidomycosis, also termed Valley fever, is a fungal infection caused by the inhalation of endospores. Once inhaled by a human host, the arthroconidia…”
Get full text

A Perioperative Blood Management Algorithm Aimed at Conservation of Platelets in Clinical Practice: The Role of the Anesthesiologist in Decision-Making by Skidmore, Kimberly L, Singh, Naina, Kallurkar, Anusha, Cagle, Hayden, Smith Iii, Van S, Varrassi, Giustino, Shekoohi, Sahar, Kaye, Alan

“…Platelet dysfunction and thrombocytopenia are associated with postoperative morbidity not only from modifiable preoperative factors but also from a lack of…”
Get full text

Teprotumumab-trbw as a Novel Monoclonal Antibody for Thyroid Eye Disease: A Literature Review by Bocklud, Brooke E, Fakhre, Waddih, Murphy, Brennan, Maddox, Kirsten, Ahmadzadeh, Shahab, Viswanath, Omar, Varrassi, Giustino, Shekoohi, Sahar, Kaye, Alan D

“…Thyroid eye disease (TED) can cause disfigurement and vision loss, most commonly in patients with Graves’ disease. These symptoms are related to orbital…”
Get full text

Prenatal Acetaminophen Exposure and its Associated Risk for Attention Deficit Hyperactivity Disorder by Spillers, Noah J., Talbot, Norris C., Luther, Patrick M., Ly, Gianni H., Roberts, Caylin J., Ahmadzadeh, Shahab, Shekoohi, Sahar, Viswanath, Omar, Kaye, Alan D.

“…Acetaminophen is one of the most commonly used over-the-counter antipyretic and analgesic drugs on the market and has been relevant in the medical world for…”
Get full text

The Role of Dopamine in Impulsivity and Substance Abuse: A Narrative Review by Plaisance, Connor J, Ledet III, Lloyd F, Slusher, Nicholas J, Daniel, Charles P, Lee, Zachary, Dorius, Bradley, Barrie, Sonnah, Parker-Actlis, Tomasina Q, Ahmadzadeh, Shahab, Shekoohi, Sahar, Kaye, Alan D

“…Substance use disorder (SUD), based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), is defined by symptoms caused by…”
Get full text

Lyme Disease and Post-treatment Lyme Disease Syndrome: Current and Developing Treatment Options by Talbot, Norris C, Spillers, Noah J, Luther, Patrick, Flanagan, Chelsi, Soileau, Lenise G, Ahmadzadeh, Shahab, Viswanath, Omar, Varrassi, Giustino, Shekoohi, Sahar, Cornett, Elyse M, Kaye, Adam M, Kaye, Alan D

“…Lyme disease and its treatment implications have become an ever-increasing area of concern within the United States related to the markedly increased…”
Get full text

Clinical Considerations and Outcomes of Robotic Urologic Surgery in Obese Patients by Khater, Nazih, Morris, Anna G., Vanvalkenburg, Delena M., Garcia, Andrew J., Jin, Kevin, Ahmadzadeh, Shahab, Shekoohi, Sahar, Cornett, Elyse M., Kaye, Alan David

“…Obesity is associated with many significant physiological changes. These considerations are important to surgery, especially in urological procedures. Obese…”
Get full text

Telemedicine, E-Health, and Multi-Agent Systems for Chronic Pain Management by Ahmed Kamal, Manar, Ismail, Zainab, Shehata, Islam Mohammad, Djirar, Soumia, Talbot, Norris C., Ahmadzadeh, Shahab, Shekoohi, Sahar, Cornett, Elyse M., Fox, Charles J., Kaye, Alan D.

“…Telemedicine, telehealth, and E-health all offer significant benefits for pain management and healthcare services by fostering the physician–patient…”
Get full text