Search Results - "Sheinman, Michael"

Stress controls the mechanics of collagen networks by Licup, Albert James, Münster, Stefan, Sharma, Abhinav, Sheinman, Michael, Jawerth, Louise M., Fabry, Ben, Weitz, David A., MacKintosh, Fred C.

“…Collagen is the main structural and load-bearing element of various connective tissues, where it forms the extracellular matrix that supports cells. It has…”
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Identical sequences found in distant genomes reveal frequent horizontal transfer across the bacterial domain by Sheinman, Michael, Arkhipova, Ksenia, Arndt, Peter F, Dutilh, Bas E, Hermsen, Rutger, Massip, Florian

“…Horizontal gene transfer (HGT) is an essential force in microbial evolution. Despite detailed studies on a variety of systems, a global picture of HGT in the…”
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The effects of intersegmental transfers on target location by proteins by Sheinman, Michael, Kafri, Yariv

“…We study a model of protein searching for a target, using facilitated diffusion, on a DNA molecule confined in a finite volume. The model includes three…”
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Statistical properties of pairwise distances between leaves on a random Yule tree by Sheinman, Michael, Massip, Florian, Arndt, Peter F

“…A Yule tree is the result of a branching process with constant birth and death rates. Such a process serves as an instructive null model of many empirical…”
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Modeling the mosaic structure of bacterial genomes to infer their evolutionary history by Sheinman, Michael, Arndt, Peter F, Massip, Florian

“…The chronology and phylogeny of bacterial evolution are difficult to reconstruct due to a scarce fossil record. The analysis of bacterial genomes remains…”
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Exact sequence matches in genomic studies by Sheinman, Michael

“…The purpose of this article is to review usage of exact sequence matches in different field of genomic studies. Methods. The presentation is built in the form…”
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Molecular motors robustly drive active gels to a critically connected state by Alvarado, José, Sheinman, Michael, Sharma, Abhinav, MacKintosh, Fred C., Koenderink, Gijsje H.

“…Living systems naturally exhibit internal driving: active, molecular processes drive non-equilibrium phenomena such as metabolism or migration. Active gels…”
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Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer by Lips, Esther H., Kumar, Tapsi, Megalios, Anargyros, Visser, Lindy L., Sheinman, Michael, Fortunato, Angelo, Shah, Vandna, Hoogstraat, Marlous, Sei, Emi, Mallo, Diego, Roman-Escorza, Maria, Ahmed, Ahmed A., Xu, Mingchu, van den Belt-Dusebout, Alexandra W., Brugman, Wim, Casasent, Anna K., Clements, Karen, Davies, Helen R., Fu, Liping, Grigoriadis, Anita, Hardman, Timothy M., King, Lorraine M., Krete, Marielle, Kristel, Petra, de Maaker, Michiel, Maley, Carlo C., Marks, Jeffrey R., Menegaz, Brian A., Mulder, Lennart, Nieboer, Frank, Nowinski, Salpie, Pinder, Sarah, Quist, Jelmar, Salinas-Souza, Carolina, Schaapveld, Michael, Schmidt, Marjanka K., Shaaban, Abeer M., Shami, Rana, Sridharan, Mathini, Zhang, John, Stobart, Hilary, Collyar, Deborah, Nik-Zainal, Serena, Wessels, Lodewyk F. A., Hwang, E. Shelley, Navin, Nicholas E., Futreal, P. Andrew, Thompson, Alastair M., Wesseling, Jelle, Sawyer, Elinor J.

“…Ductal carcinoma in situ (DCIS) is the most common form of preinvasive breast cancer and, despite treatment, a small fraction (5–10%) of DCIS patients develop…”
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Conditions for positioning of nucleosomes on DNA by Sheinman, Michael, Chung, Ho-Ryun

“…Positioning of nucleosomes along a eukaryotic genome plays an important role in its organization and regulation. There are many different factors affecting the…”
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A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression by Hutten, Stefan J., de Bruijn, Roebi, Lutz, Catrin, Badoux, Madelon, Eijkman, Timo, Chao, Xue, Ciwinska, Marta, Sheinman, Michael, Messal, Hendrik, Herencia-Ropero, Andrea, Kristel, Petra, Mulder, Lennart, van der Waal, Rens, Sanders, Joyce, Almekinders, Mathilde M., Llop-Guevara, Alba, Davies, Helen R., van Haren, Matthijs J., Martin, Nathaniel I., Behbod, Fariba, Nik-Zainal, Serena, Serra, Violeta, van Rheenen, Jacco, Lips, Esther H., Wessels, Lodewyk F.A., Wesseling, Jelle, Scheele, Colinda L.G.J., Jonkers, Jos

“…Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer (IBC). Due to a lack of biomarkers able to distinguish high- from…”
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Ductal carcinoma in situ develops within clonal fields of mutant cells in morphologically normal ducts by Hutten, Stefan J, Messal, Hendrik A, Lips, Esther H, Sheinman, Michael, Ciwinska, Marta, Braams, Esmee, Borden, Carolien, Kristel, Petra, Stoffers, Saskia, Wessels, Lodewyk FA, Wesseling, Jelle, Jonkers, Jos, Rheenen, Jacco, Lips, Esther H, Schmidt, Marjanka, Wessels, Lodewyk FA, Bhattacharjee, Proteeti, Thompson, Alastair, Nik‐Zainal, Serena, Davies, Helen, Sawyer, Elinor J, Futreal, Andrew, Navin, Nicholas, Hwang, Shelley, Behbod, Fariba, Rea, Daniel, Stobart, Hilary, Collyar, Deborah, Pinto, Donna, Verschuur, Ellen, Oirsouw, Marja, Jonkers, Jos, Rheenen, Jacco, Wesseling, Jelle, Scheele, Colinda LGJ

“…Mutations are abundantly present in tissues of healthy individuals, including the breast epithelium. Yet it remains unknown whether mutant cells directly…”
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How evolution of genomes is reflected in exact DNA sequence match statistics by Massip, Florian, Sheinman, Michael, Schbath, Sophie, Arndt, Peter F

“…Genome evolution is shaped by a multitude of mutational processes, including point mutations, insertions, and deletions of DNA sequences, as well as segmental…”
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Abstract P1-22-05: Identifying predictors of invasive recurrence based on molecular profiles of DCIS lesions by Bismeijer, Tycho, Ahmed, Ahmed A, Sheinman, Michael, Roman-Escorza, Maria, Shah, Vandna, Marks, Jeffrey R, King, Lorraine M, Megalios, Anargyros, Visser, Lindy L, Hoogstraat, Marlous, Davies, Helen R, Kumar, Tapsi, Collyar, Deborah, Stobart, Hilary, Navin, Nicholas N, Futreal, Andrew, Nik-Zainal, Serena, Hwang, Shelley, Lips, Esther H, Thompson, Alastair, Wessels, Lodewyk FA, Sawyer, Elinor J, Wesseling, Jelle

“…Abstract Introduction Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer. Patients with DCIS are routinely treated by…”
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Evolutionary dynamics of selfish DNA explains the abundance distribution of genomic subsequences by Sheinman, Michael, Ramisch, Anna, Massip, Florian, Arndt, Peter F.

“…Since the sequencing of large genomes, many statistical features of their sequences have been found. One intriguing feature is that certain subsequences are…”
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Comparing the Statistical Fate of Paralogous and Orthologous Sequences by Massip, Florian, Sheinman, Michael, Schbath, Sophie, Arndt, Peter F

“…For several decades, sequence alignment has been a widely used tool in bioinformatics. For instance, finding homologous sequences with a known function in…”
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Abstract PR002: Genomic predictor can discriminate between high- and low-risk DCIS by Escorza, Maria Roman, Sheinman, Michael, Bismeijer, Tycho, Ahmed, Ahmed A., Shah, Vandna, Marks, Jeffrey R., King, Lorraine M., Megalios, Anargyros, Visser, Lindy L., Hoogstrat, Marlous, Davies, Helen R., Kumar, Tapsi, Collyar, Deborah, Stobart, Hilary, Pinder, Sarah, Navin, Nicholas N., Futreal, Andrew, Nik-Zainal, Serena, Hwang, E. Shelley, Lips, Esther H., Thompson, Alastair, Wessels, Lodewyk F.A., Wesseling, Jelle, Sawyer, Elinor J.

“…Abstract Introduction: Ductal carcinoma in situ (DCIS) is considered a non-obligate precursor of invasive ductal carcinoma. With the aim of preventing a…”
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Decay of quantum accelerator modes by Sheinman, Michael, Fishman, Shmuel, Guarneri, Italo, Rebuzzini, Laura

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Myosin Activity Drives Cytoskeletal Networks to a Critically Connected State by Alvarado, Jose R., Sheinman, Michael, Sharma, Abhinav, MacKintosh, Fred, Koenderink, Gijsje

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Comparing the Statistical Fate of Paralogous and Orthologous Sequences by Massip, Florian, Sheinman, Michael, Schbath, Sophie, Arndt, Peter

“…For several decades, sequence alignment has been a widely used tool in bioinformatics. For instance, finding homologous sequences with a known function in…”
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Abstract 5108: Copy number analysis of pure DCIS and association with recurrence by Ahmed, Ahmed A., Roman-Escorza, Maria, Bismeijer, Tycho, Sheinman, Michael, Shah, Vandna, Shami, Rana, Marks, Jeffrey R., King, Lorraine M., Megalios, Anargyros, Visser, Lindy L., Hoogstraat, Marlous, Davies, Helen R., Kumar, Tapsi, Collyar, Deborah, Stobart, Hilary, Pinder, Sarah, Navin, Nicholas N., Futreal, Andrew, Nik-Zainal, Serena, Hwang, E. Shelley, Wessels, Lodewyk F., Lips, Esther H., Thompson, Alastair, Wesseling, Jelle, Sawyer, Elinor J.

“…Abstract With the widespread adoption of breast cancer screening the incidence of pure ductal carcinoma in situ (DCIS) has increased. As DCIS is considered a…”
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