Search Results - "Sheila N. Lopez Acevedo"

Ultrasonically-guided flow focusing generates precise emulsion droplets for high-throughput single cell analyses by Lagerman, Colton E., López Acevedo, Sheila N., Fahad, Ahmed S., Hailemariam, Amen T., Madan, Bharat, DeKosky, Brandon J.

“…Emulsion-based techniques have dramatically advanced our understanding of single-cell biology and complex single-cell features over the past two decades. Most…”
Get full text

Molecular probes of spike ectodomain and its subdomains for SARS-CoV-2 variants, Alpha through Omicron by Teng, I-Ting, Nazzari, Alexandra F, Choe, Misook, Liu, Tracy, Oliveira de Souza, Matheus, Petrova, Yuliya, Tsybovsky, Yaroslav, Wang, Shuishu, Zhang, Baoshan, Artamonov, Mykhaylo, Madan, Bharat, Huang, Aric, Lopez Acevedo, Sheila N, Pan, Xiaoli, Ruckwardt, Tracy J, DeKosky, Brandon J, Mascola, John R, Misasi, John, Sullivan, Nancy J, Zhou, Tongqing, Kwong, Peter D

“…Since the outbreak of the COVID-19 pandemic, widespread infections have allowed SARS-CoV-2 to evolve in human, leading to the emergence of multiple circulating…”
Get full text

Cell activation-based screening of natively paired human T cell receptor repertoires by Fahad, Ahmed S., Chung, Cheng Yu, López Acevedo, Sheila N., Boyle, Nicoleen, Madan, Bharat, Gutiérrez-González, Matías F., Matus-Nicodemos, Rodrigo, Laflin, Amy D., Ladi, Rukmini R., Zhou, John, Wolfe, Jacy, Llewellyn-Lacey, Sian, Koup, Richard A., Douek, Daniel C., Balfour, Henry H., Price, David A., DeKosky, Brandon J.

“…Adoptive immune therapies based on the transfer of antigen-specific T cells have been used successfully to treat various cancers and viral infections, but…”
Get full text

Large-scale antibody immune response mapping of splenic B cells and bone marrow plasma cells in a transgenic mouse model by Pan, Xiaoli, López Acevedo, Sheila N, Cuziol, Camille, De Tavernier, Evelyn, Fahad, Ahmed S, Longjam, Priyobarta S, Rao, Sambasiva P, Aguilera-Rodríguez, David, Rezé, Mathilde, Bricault, Christine A, Gutiérrez-González, Matías F, de Souza, Matheus Oliveira, DiNapoli, Joshua M, Vigne, Emmanuelle, Shahsavarian, Melody A, DeKosky, Brandon J

“…Molecular characterization of antibody immunity and human antibody discovery is mainly carried out using peripheral memory B cells, and occasionally…”
Get full text

Mapping monoclonal anti-SARS-CoV-2 antibody repertoires against diverse coronavirus antigens by de Souza, Matheus Oliveira, Madan, Bharat, Teng, I-Ting, Huang, Aric, Liu, Lihong, Fahad, Ahmed S., Lopez Acevedo, Sheila N., Pan, Xiaoli, Sastry, Mallika, Gutierrez-Gonzalez, Matias, Yin, Michael T., Zhou, Tongqing, Ho, David D., Kwong, Peter D., DeKosky, Brandon J.

“…Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have emerged continuously, challenging the effectiveness of vaccines, diagnostics, and…”
Get full text

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes by Zhou, Tongqing, Teng, I-Ting, Olia, Adam S., Cerutti, Gabriele, Gorman, Jason, Nazzari, Alexandra, Shi, Wei, Tsybovsky, Yaroslav, Wang, Lingshu, Wang, Shuishu, Zhang, Baoshan, Zhang, Yi, Katsamba, Phinikoula S., Petrova, Yuliya, Banach, Bailey B., Fahad, Ahmed S., Liu, Lihong, Lopez Acevedo, Sheila N., Madan, Bharat, Oliveira de Souza, Matheus, Pan, Xiaoli, Wang, Pengfei, Wolfe, Jacy R., Yin, Michael, Ho, David D., Phung, Emily, DiPiazza, Anthony, Chang, Lauren A., Abiona, Olubukola M., Corbett, Kizzmekia S., DeKosky, Brandon J., Graham, Barney S., Mascola, John R., Misasi, John, Ruckwardt, Tracy, Sullivan, Nancy J., Shapiro, Lawrence, Kwong, Peter D.

“…Biotin-labeled molecular probes, comprising specific regions of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike, would be helpful in the…”
Get full text

Antibody screening at reduced pH enables preferential selection of potently neutralizing antibodies targeting SARS‐CoV‐2 by Madan, Bharat, Reddem, Eswar R., Wang, Pengfei, Casner, Ryan G., Nair, Manoj S., Huang, Yaoxing, Fahad, Ahmed S., Souza, Matheus Oliveira, Banach, Bailey B., López Acevedo, Sheila N., Pan, Xiaoli, Nimrania, Rajani, Teng, I‐Ting, Bahna, Fabiana, Zhou, Tongqing, Zhang, Baoshan, Yin, Michael T., Ho, David D., Kwong, Peter D., Shapiro, Lawrence, DeKosky, Brandon J.

“…Antiviral monoclonal antibody (mAb) discovery enables the development of antibody‐based antiviral therapeutics. Traditional antiviral mAb discovery relies on…”
Get full text

Immortalization and functional screening of natively paired human T cell receptor repertoires by Fahad, Ahmed S, Chung, Cheng-Yu, Lopez Acevedo, Sheila N, Boyle, Nicoleen, Madan, Bharat, Gutiérrez-González, Matias F, Matus-Nicodemos, Rodrigo, Laflin, Amy D, Ladi, Rukmini R, Zhou, John, Wolfe, Jacy, Llewellyn-Lacey, Sian, Koup, Richard A, Douek, Daniel C, Balfour Jr, Henry H, Price, David A, DeKosky, Brandon J

“…Abstract Functional analyses of the T cell receptor (TCR) landscape can reveal critical information about protection from disease and molecular responses to…”
Get full text

Quality Control: Chain Pairing Precision and Monitoring of Cross-Sample Contamination: A Method by the AIRR Community by Chung, Cheng-Yu, Gutiérrez-González, Matías, López Acevedo, Sheila N, Fahad, Ahmed S, DeKosky, Brandon J

“…New approaches in high-throughput analysis of immune receptor repertoires are enabling major advances in immunology and for the discovery of precision…”
Get more information

Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses by Banach, Bailey B., Cerutti, Gabriele, Fahad, Ahmed S., Shen, Chen-Hsiang, Oliveira De Souza, Matheus, Katsamba, Phinikoula S., Tsybovsky, Yaroslav, Wang, Pengfei, Nair, Manoj S., Huang, Yaoxing, Francino-Urdániz, Irene M., Steiner, Paul J., Gutiérrez-González, Matías, Liu, Lihong, López Acevedo, Sheila N., Nazzari, Alexandra F., Wolfe, Jacy R., Luo, Yang, Olia, Adam S., Teng, I-Ting, Yu, Jian, Zhou, Tongqing, Reddem, Eswar R., Bimela, Jude, Pan, Xiaoli, Madan, Bharat, Laflin, Amy D., Nimrania, Rajani, Yuen, Kwok-Yung, Whitehead, Timothy A., Ho, David D., Kwong, Peter D., Shapiro, Lawrence, DeKosky, Brandon J.

“…Understanding mechanisms of protective antibody recognition can inform vaccine and therapeutic strategies against SARS-CoV-2. We report a monoclonal antibody,…”
Get full text

Molecular probes of spike ectodomain and its subdomains for SARS-CoV-2 variants, Alpha through Omicron by I-Ting Teng, Alexandra F. Nazzari, Misook Choe, Tracy Liu, Matheus Oliveira de Souza, Yuliya Petrova, Yaroslav Tsybovsky, Shuishu Wang, Baoshan Zhang, Mykhaylo Artamonov, Bharat Madan, Aric Huang, Sheila N. Lopez Acevedo, Xiaoli Pan, Tracy J. Ruckwardt, Brandon J. DeKosky, John R. Mascola, John Misasi, Nancy J. Sullivan, Tongqing Zhou, Peter D. Kwong

“…Since the outbreak of the COVID-19 pandemic, widespread infections have allowed SARS-CoV-2 to evolve in human, leading to the emergence of multiple circulating…”
Get full text