Search Results - "Sheila Macpherson"

Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells by Kilcoyne, Karen R, Smith, Lee B, Atanassova, Nina, Macpherson, Sheila, McKinnell, Chris, van den Driesche, Sander, Jobling, Matthew S, Chambers, Thomas J G, De Gendt, Karel, Verhoeven, Guido, O'Hara, Laura, Platts, Sophie, Renato de Franca, Luiz, Lara, Nathália L M, Anderson, Richard A, Sharpe, Richard M

“…Fetal growth plays a role in programming of adult cardiometabolic disorders, which in men, are associated with lowered testosterone levels. Fetal growth and…”
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Dibutyl phthalate induced testicular dysgenesis originates after seminiferous cord formation in rats by Lara, Nathália L. M., van den Driesche, Sander, Macpherson, Sheila, França, Luiz R., Sharpe, Richard M.

“…Administration of dibutyl phthalate (DBP) to pregnant rats causes reproductive disorders in male offspring, resulting from suppression of intratesticular…”
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Diethylstilboestrol exposure does not reduce testosterone production in human fetal testis xenografts by Mitchell, Rod T, Sharpe, Richard M, Anderson, Richard A, McKinnell, Chris, Macpherson, Sheila, Smith, Lee B, Wallace, W Hamish B, Kelnar, Christopher J H, van den Driesche, Sander

“…In rodents, in utero exposure to exogenous estrogens including diethylstilboestrol (DES) results in major suppression of steroidogenesis in fetal testes…”
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Expression of oestrogen receptors, ERα, ERβ, and ERβ variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERα by Collins, Frances, MacPherson, Sheila, Brown, Pamela, Bombail, Vincent, Williams, Alistair RW, Anderson, Richard A, Jabbour, Henry N, Saunders, Philippa TK

“…BACKGROUND: Endometrial cancer is the most common gynaecological malignancy; risk factors include exposure to oestrogens and high body mass index. Expression…”
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Experimentally induced testicular dysgenesis syndrome originates in the masculinization programming window by van den Driesche, Sander, Kilcoyne, Karen R., Wagner, Ida, Rebourcet, Diane, Boyle, Ashley, Mitchell, Rod, McKinnell, Chris, Macpherson, Sheila, Donat, Roland, Shukla, Chitranjan J., Jorgensen, Anne, Meyts, Ewa Rajpert-De, Skakkebaek, Niels E., Sharpe, Richard M.

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Effects of Exposure to Acetaminophen and Ibuprofen on Fetal Germ Cell Development in Both Sexes in Rodent and Human Using Multiple Experimental Systems by Hurtado-Gonzalez, Pablo, Anderson, Richard A, Macdonald, Joni, van den Driesche, Sander, Kilcoyne, Karen, Jørgensen, Anne, McKinnell, Chris, Macpherson, Sheila, Sharpe, Richard M, Mitchell, Rod T

“…Analgesic exposure during pregnancy may affect aspects of fetal gonadal development that are targeted by endocrine disruptors. We investigated whether…”
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Comparative effects of di(n-butyl) phthalate exposure on fetal germ cell development in the rat and in human fetal testis xenografts by van den Driesche, Sander, McKinnell, Chris, Calarrão, Ana, Kennedy, Laura, Hutchison, Gary R, Hrabalkova, Lenka, Jobling, Matthew S, Macpherson, Sheila, Anderson, Richard A, Sharpe, Richard M, Mitchell, Rod T

“…Phthalate exposure induces germ cell effects in the fetal rat testis. Although experimental models have shown that the human fetal testis is insensitive to the…”
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Analgesic exposure in pregnant rats affects fetal germ cell development with inter-generational reproductive consequences by Dean, Afshan, van den Driesche, Sander, Wang, Yili, McKinnell, Chris, Macpherson, Sheila, Eddie, Sharon L., Kinnell, Hazel, Hurtado-Gonzalez, Pablo, Chambers, Tom J., Stevenson, Kerrie, Wolfinger, Elke, Hrabalkova, Lenka, Calarrao, Ana, Bayne, Rosey AL, Hagen, Casper P., Mitchell, Rod T., Anderson, Richard A., Sharpe, Richard M.

“…Analgesics which affect prostaglandin (PG) pathways are used by most pregnant women. As germ cells (GC) undergo developmental and epigenetic changes in fetal…”
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Publisher Correction: Dibutyl phthalate induced testicular dysgenesis originates after seminiferous cord formation in rats by Lara, Nathália L. M., van den Driesche, Sander, Macpherson, Sheila, França, Luiz R., Sharpe, Richard M.

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
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In Silico Analysis Identifies a Novel Role for Androgens in the Regulation of Human Endometrial Apoptosis by Marshall, Elaine, Lowrey, Jacqueline, MacPherson, Sheila, Maybin, Jacqueline A, Collins, Frances, Critchley, Hilary O. D, Saunders, Philippa T. K

“…Context: The endometrium is a multicellular, steroid-responsive tissue that undergoes dynamic remodeling every menstrual cycle in preparation for implantation…”
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Experimentally induced testicular dysgenesis syndrome originates in the masculinization programming window by van den Driesche, Sander, Kilcoyne, Karen R, Wagner, Ida, Rebourcet, Diane, Boyle, Ashley, Mitchell, Rod, McKinnell, Chris, Macpherson, Sheila, Donat, Roland, Shukla, Chitranjan J, Jorgensen, Anne, Meyts, Ewa Rajpert-De, Skakkebaek, Niels E, Sharpe, Richard M

“…The testicular dysgenesis syndrome (TDS) hypothesis, which proposes that common reproductive disorders of newborn and adult human males may have a common fetal…”
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Identification of transcription factors and coactivators affected by dibutylphthalate interactions in fetal rat testes by Plummer, Simon M, Dan, Dhritiman, Quinney, Joanne, Hallmark, Nina, Phillips, Richard D, Millar, Michael, Macpherson, Sheila, Elcombe, Clifford R

“…Previous analysis of in utero dibutylphthalate (DBP)-exposed fetal rat testes indicated that DBP's antiandrogenic effects were mediated, in part, by indirect…”
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Estrogen receptor related beta is expressed in human endometrium throughout the normal menstrual cycle by Bombail, Vincent, MacPherson, Sheila, Critchley, Hilary O.D., Saunders, Philippa T.K.

“…BACKGROUND Estrogen receptor related beta (ERRβ, ESRRB/NR3B2) is an orphan receptor that shares significant sequence homology with estrogen receptors ERα and…”
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A Role for the Orphan Nuclear Receptor Estrogen-Related Receptor α in Endometrial Stromal Cell Decidualization and Expression of Genes Implicated in Energy Metabolism by Bombail, Vincent, Gibson, Douglas A, Collins, Frances, MacPherson, Sheila, Critchley, Hilary O. D, Saunders, Philippa T. K

“…Context: Differentiation (decidualization) of endometrial stromal cells (ESC) is an essential prerequisite for successful implantation and establishment of…”
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S3-4: Species differences in susceptibility to inhibition of fetal testis steroidogenesis by van den Driesche, Sander, Mitchell, Rod T., Walker, Marion, McKinnell, Chris, Macpherson, Sheila, Drake, Amanda J., Anderson, Richard A., Sharpe, Richard M.

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Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells by Kilcoyne, Karen R., Smith, Lee B., Atanassova, Nina, Macpherson, Sheila, McKinnell, Chris, van den Driesche, Sander, Jobling, Matthew S., Chambers, Thomas J. G., De Gendt, Karel, Verhoeven, Guido, O'Hara, Laura, Platts, Sophie, de Franca, Luiz Renato, Lara, Nathália L. M., Anderson, Richard A., Sharpe, Richard M.

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Differential expression of oestrogen receptor α and β proteins in the testes and male reproductive system of human and non-human primates by Saunders, Philippa T.K., Sharpe, Richard M., Williams, Karin, Macpherson, Sheila, Urquart, Holly, Irvine, D.Stewart, Millar, Michael R.

“…The role(s) oestrogens play in male adult reproductive function remains uncertain. We have used antibodies specific for oestrogen receptor- α (ERα) and - β…”
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Susceptibility of the Fetal Testis to Disruption by Environmental Factors: Mechanisms and Species Differences by Sharpe, Richard M., Mitchell, Rod T., Dean, Afshan, Kilcoyne, Karen, Jobling, Matthew, Macpherson, Sheila, McKinnell, Chris, Anderson, Richard A., Boyle, Ashley, Platts, Sophie, Childs, Andrew, van den Driesche, Sander

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Differential Expression of Estrogen Receptor-α and -β and Androgen Receptor in the Ovaries of Marmosets and Humans by Saunders, Philippa T. K, Millar, Michael R, Williams, Karin, Macpherson, Sheila, Harkiss, Diana, Anderson, Richard A, Orr, Brigid, Groome, Nigel P, Scobie, Graeme, Fraser, Hamish M

“…Estrogens and androgens are essential for the maturation of the ovarian follicle and normal fertility in the female. We have used antibodies specific for both…”
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A Role for the Orphan Nuclear Receptor Estrogen-Related Receptor α in Endometrial Stromal Cell Decidualization and Expression of Genes Implicated in Energy Metabolism by Bombail, Vincent, Gibson, Douglas, Collins, Frances, MacPherson, Sheila, Critchley, Hilary O. D, Saunders, Philippa T. K

“…This article appears in The Journal of Clinical Endocrinology & Metabolism. 10.1210/jc.2010-0154…”
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