Search Results - "Sheikin, D S"

Dexoxadrol and its bioisosteres: structure, synthesis, and pharmacological activity by Novakov, I. A., Sheikin, D. S., Navrotskii, M. B., Mkrtchyan, A. S., Brunilina, L. L., Balakin, K. V.

“…The review addresses the complete anthology of the development and evolution of dexoxadrol derivatives comprising a class of highly efficient NMDA receptor…”
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Regiospecific S-aminoalkylation of 5-substituted 6-hydroxy-2-thiouracil derivatives in the synthesis of structural analogs of isothiobarbamine by Novakov, I. A., Sheikin, D. S., Chapurkin, V. V., Nawrozkij, M. B., Korenkov, B. D., Kirillov, I. A., Deshevov, P. P., Vostrikova, O. V., Brunilina, L. L.

“…Regiospecific S -monoaminoalkylation of 5-substituted derivatives of 6-hydroxy-2-thiouracil with free N,N -dialkyl- N -(2-chloroethyl)amines in anhydrous Pr i…”
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Synthesis and biological properties of novel structural analogs of isothiobarbamine by Novakov, I. A., Sheikin, D. S., Ruchko, E. A., Brunilina, L. L., Vernigora, A. A., Salykin, N. A., Vostrikova, O. V., Chapurkin, V. V., Nawrozkij, M. B., Kurkin, D. V., Bakulin, D. A., Vorontsov, M. Yu, Sablina, L. A., Kovalev, N. S., Tyurenkov, I. N.

“…Novel structural analogs of isothiobarbamine, which differ from the prototype scaffold by the substituent at position 2 of the pyrimidine heterocycle, were for…”
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Aminolysis of 6-[1-(2,6-difluorophenyl)cyclopropyl]-5-methyl-2-(nitroamino)pyrimidin-4(3H)-one by Novakov, I. A., Brunilina, L. L., Vernigora, A. A., Kirillov, I. A., Mkrtchyan, A. S., Navrotskii, M. B., Sheikin, D. S., Yablokov, A. S., Ruchko, E. A., Kachala, V. V.

“…The aminolysis of 6-[1-(2,6-difluorophenyl)cyclopropyl]-5-methyl-2-(nitroamino)pyrimidin-4(3 H )-one with various amines in butan-1-ol and under solvent-free…”
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Potential Synthetic Adaptogens. II. Synthesis and Pharmacological Activity of New Conformationally Labile Bromantane Analogs, N-[(Adamantan-1-YL)Methyl]-4-Bromoanilines by Babushkin, A. S., Navrotskii, M. B., Novakov, I. A., Orlinson, B. S., Robinovich, M. D., Sheikin, D. S., Voloboev, S. N.

“…New structural analogs of bromantane with greater conformational lability than the prototype were synthesized. Their physiological activity profiles were…”
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Specific features of amidoalkylation of 6-hydroxy-5-isopropyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one by Novakov, I. A., Sheikin, D. S., Chapurkin, V. V., Nawrozkij, M. B., Kirillov, I. A., Ruchko, E. A.

“…During the synthesis of new structural analogs of isothiobarbamine, the amidoalkylation of 6-hydroxy-5-isopropyl-2-thioxo-2,3-dihydropyrimidin-4(1 H )-one was…”
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Some Features of the Tscherniac‒Einhorn Reaction with 2-Thiouracil Derivatives by Novakov, I. A., Sheikin, D. S., Chapurkin, V. V., Navrotskii, M. B., Babushkin, A. S., Ruchko, E. A., Maryshev, A. Yu, Schols, D.

“…The Tscherniac–Einhorn reaction of 6-methyl and 6-(trifluoromethyl) derivatives of 2-thiouracil with N -(bromomethyl)phthalimide in under basic catalysis leads…”
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Some Features of the TscherniacâEinhorn Reaction with 2-Thiouracil Derivatives by Novakov, I. A, Sheikin, D. S, Chapurkin, V. V, Navrotskii, M. B, Babushkin, A. S, Ruchko, E. A, Maryshev, A. Yu

“…The Tscherniac-Einhorn reaction of 6-methyl and 6-(trifluoromethyl)derivatives of 2-thiouracil with N-(bromomethyl)phthalimide in under basic catalysis leads…”
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Some Features of the Tscherniac‒Einhorn Reaction with2-Thiouracil Derivatives by Novakov, I A, Sheikin, D S, Chapurkin, V V, Navrotskii, M B, Babushkin, A S, Ruchko, E A, Yu, Maryshev A, Schols, D

“…The Tscherniac–Einhorn reaction of 6-methyl and 6-(trifluoromethyl) derivatives of 2-thiouracil with N-(bromomethyl)phthalimide in under basic catalysis leads…”
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