Search Results - "Shegai, P V"

PSMA-Targeted Radiopharmaceuticals for Imaging and Therapy of Prostate Cancer by Tishchenko, V. K., Petriev, V. M., Vlasova, O. P., Krylov, V. V., Shegai, P. V., Ivanov, S. A., Kaprin, A. D.

“…Molecular changes in prostate cancer lead to increased expression of prostate-specific membrane antigen (PSMA), which is a suitable target for imaging and…”
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Challenges Faced by Clinicians in the Personalized Treatment Planning: A Literature Review and the First Results of the Russian National Cancer Program by Shegai, P. V., Shatalov, P. A., Zabolotneva, A. A., Falaleeva, N. A., Ivanov, S. A., Kaprin, A. D.

“…Advances in cancer molecular profiling have enabled the development of more effective approaches to the diagnosis and personalized treatment of tumors…”
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Preclinical Study of Therapeutic Efficacy of a New Russian Radiopharmaceutical 177Lu-DOTA-PSMA by Tishchenko, V. K., Vlasova, O. P., Lebedeva, A. A., Fedorova, A. V., Pankratov, A. A., Morozova, N. B., Kuzenkova, K. A., Stepchenkova, E. D., Shegai, P. V., Ivanov, S. A., Kaprin, A. D.

“…The therapeutic efficacy of a Russian radiopharmaceutical 177 Lu-DOTA-PSMA was studied in vivo using male BALB/c nu/nu (nude) mice with prostate carcinoma…”
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Cytostatic Activity of Combretastatin A-4 Derivatives in an In Vitro System by Plyutinskaya, A. D., Nemtsova, E. R., Pankratov, A. A., Shegai, P. V., Krylov, S. S., Iskandarova, V. N., Maksimenko, A. S., Demchuk, D. V., Kuptsova, T. S., Semenova, M. N., Semenov, V. V.

“…Cytostatic activity of combretastatin A-4, its 11 analogues, and paclitaxel (Taxacad) was evaluated in vitro on human tumor cells A549 (lung adenocarcinoma)…”
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Minimally Manipulated Bone Marrow-Derived Cells Can Be Used for Tissue Engineering In Situ and Simultaneous Formation of Personalized Tissue Models by Baranovskii, D. S., Akhmedov, B. G., Demchenko, A. G., Krasheninnikov, M. E., Balyasin, M. V., Pavlova, O. Yu, Serova, N. S., Krasil’nikova, O. A., Shegai, P. V., Kaprin, A. D., Klabukov, I. D.

“…Red bone marrow and autologous bone tissue (bone fragments and bone chips) of the donor were harvested intraoperatively during autoplasty of talus bone defect…”
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Evaluation of the Association of rs4680 COMT Polymorphism and Clinical Parameters of the Tumor in Colorectal Cancer (a Pilot Study) by Ivanova, T. I., Potapov, A. L., Zemskova, D. V., Khorokhorina, V. A., Shegai, P. V., Ivanov, S. A., Kaprin, A. D.

“…We analyzed association of rs4680 polymorphism of catechol-O-methyltransferase ( COMT ) gene with clinical parameters of the tumor in patients with colorectal…”
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Prospects for the Application of Methods of Evolutionary Biology in Oncology by Potievskii, M. B., Shegai, P. V., Kaprin, A. D.

“…Oncological diseases is the second leading cause of death among noninfectious diseases in Russia and worldwide. Evolutionary medicine is a relatively new…”
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Biodistribution of 213Bi–Metallothionein and 213Bi–IgG in Intact Mice by Petriev, V. M., Tishchenko, V. K., Shegai, P. V., Ivanov, S. A., Kaprin, A. D.

“…One of the important problems of radiopharmaceutics is the development of new approaches for the creation of radiopharmaceuticals based on antibodies while…”
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Genetic and therapeutic landscapes in cohort of pancreatic adenocarcinomas: next-generation sequencing and machine learning for full tumor exome analysis by Shatalov, P A, Falaleeva, N A, Bykova, E A, Korostin, D O, Belova, V A, Zabolotneva, A A, Shinkarkina, A P, Gorbachev, A Yu, Potievskiy, M B, Surkova, V S, Khailova, Zh V, Kulemin, N A, Baranovskii, Denis, Kostin, A A, Kaprin, A D, Shegai, P V

“…About 7% of all cancer deaths are caused by pancreatic cancer (PCa). PCa is known for its lowest survival rates among all oncological diseases and heterogenic…”
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Experimental Study of 99mTc-Metallothionein Biodistribution in Intact Animals by Tishchenko, V. K., Lebedeva, A. A., Fedorova, A. V., Orlenko, S. P., Minaeva, N. G., Shegai, P. V., Ivanov, S. A., Kaprin, A. D.

“…Metallothioneins are a special group of low-molecular-weight proteins with metal-binding properties, which make them promising chelators for the development of…”
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Experience of cytokine therapy in the treatment of recurrent cervical cancer by Bykova, E. A., Falaleeva, N. A., Myalina, S. A., Shegai, P. V., Grivtsova, L. Yu

“…Cervical cancer is the most common malignant tumor of the female genital organs. In general, the prognosis in patients with advanced cervical cancer is…”
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Pharmacokinetic Properties of 99mTc-PSMA: A New Radiopharmaceutical for SPECT Imaging of Prostate Cancer by Tishchenko, V. K., Vlasova, O. P., Ivannikov, A. I., Dorovatovskiy, S. A., Pankratov, A. A., Morozova, N. B., Fedorova, A. V., Lebedeva, A. A., Kuzenkova, K. A., Stepchenkova, E. D., Khailov, A. M., Shegai, P. V., Ivanov, S. A., Kaprin, A. D.

“…Prostate-specific membrane antigen (PSMA), which is overexpressed in advanced prostate cancer, is a well-established target for the development of antitumor…”
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Antioxidant Properties of a Nanostructured Clathrate Complex Selenopyran with β-Cyclodextrin in Model Systems of Oxidative Stress by Dzikovskaya, L. A., Degtyareva, E. S., Shegai, P. V., Ivanov, S. A., Kaprin, A. D.

“…We studied the effect of nanostructured clathrate complex 9-phenyl-symm-octahydoselenoxanthene (selenopyran) with β-cyclodextrin on the generation of ОН·…”
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Comparative Analysis of Methods of Passive and Active Field Formation in Radiation Therapy With Carbon Ions by AN, Solovev, Gulidov, I A, Soldatov, A P, Shegai, P V, Ivanov, S A, Sergunova, K A, Kaprin, A D

“…Comparative data on the irradiation of patients with cancer with beams of carbon ions using passive field-modification methods and an active method of dose…”
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Biodistribution of 68Ga-NODA-Aminoglucose in Intact and Tumor-Bearing Mice by Tishchenko, V. K., Petriev, V. M., Mikhailovskaya, A. A., Shegai, P. V., Ivanov, S. A., Kaprin, A. D.

“…We studied the biodistribution of 68 Ga-NODA-aminoglucose ( 68 Ga-NODA-AG) in normal mice and mice with experimental model of colon adenocarcinoma tumor. It…”
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Analysis of years of life lost due to premature cancer mortality in the Russian Federation by Khailova, Zh. V., Kaprin, A. D., Omelyanovsky, V. V., Pustovalov, D. N., Agafonova, Yu. A., Kusakina, V. O., Ivanov, S. A., Shegai, P. V.

“…Background. Burden of disease estimation allows analyses to be carried out integrally, including cause and effect assessment. the rate of life years lost due…”
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Experimental Study of the Efficacy of Sodium Deoxyribonucleate Used in Combination with Co-Transplantation of Mesenchymal and Hematopoietic Stem Cells after Exposure to γ-Radiation by Pavlova, L. N., Zhavoronkov, L. P., Pavlov, V. V., Panfilova, V. V., Izmest’eva, O. S., Chibisova, O. F., Ivanov, V. L., Shegai, P. V., Kaprin, A. D.

“…We studied the possibility of using sodium deoxyribonucleate (Derinat) for improving the efficiency of co-transplantation of mesenchymal (MSC) and…”
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Oncology during the New Coronavirus Infection Pandemic by Kaprin, A. D., Sergeeva, N. S., Shegai, P. V., Alekseev, B. Ya

“…The COVID-19 pandemic has served as a catalyst for a whole layer of scientific research, including in Russia, where, since 2020, international multicenter…”
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Radioactivity distribution in the blood and urine of patients receiving systemic therapy with a 177Lu radiopharmaceutical and local (intra-articular) therapy with a 188Re radiopharmaceutical by Stepchenkova, E. D., Tishchenko, V. K., Vlasova, O. P., Petriev, V. M., Legkodimova, N. S., Krylov, V. V., Fedorova, A. V., Kuzenkova, E. A., Ostroukhoff, A. A., Shegai, P. V.

“…Pharmacokinetic parameters are important for calculating the absorbed dose; they also provide an indirect measure of the in vivo stability of…”
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Dose Field Shaping and Biological Effectiveness of the Effect of Pulsed Electron Accelerator Novac-11 on Mammalian Cells by Koryakina, E. V., Lychagin, A. A., Potetnya, V. I., Troshinа, M. V., Saburov, V. O., Moiseev, A. S., Koryakin, S. N., Ivanov, S. A., Shegai, P. V., Kaprin, A. D.

“…The development of technologies for using the Novac-11 pulsed electron accelerator in radiation therapy of animals with spontaneous neoplasms requires…”
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