Search Results - "Sheffer, Roberta"

The Major Histocompatibility Complex Gene Region and Sarcoidosis Susceptibility in African Americans by Rybicki, Benjamin A, Maliarik, Mary J, Poisson, Laila M, Sheffer, Roberta, Chen, Kang Mei, Major, Marcie, Chase, Gary A, Iannuzzi, Michael C

“…Investigators have intensively evaluated the major histocompatibility (MHC) complex for sarcoidosis susceptibility genes with the majority of reports…”
Get full text

The Natural Resistance-Associated Macrophage Protein Gene in African Americans with Sarcoidosis by Maliarik, Mary J, Chen, Kang Mei, Sheffer, Roberta G, Rybicki, Benjamin A, Major, Marcie L, Popovich, John, Jr, Iannuzzi, Michael C

“…The histologic and clinical similarities between tuberculosis and sarcoidosis suggest a shared underlying pathophysiology. Human natural resistance-associated…”
Get full text

The influence of T cell receptor and cytokine genes on sarcoidosis susceptibility in African Americans by Rybicki, Benjamin A, Maliarik, Mary J, Malvitz, Emily, Sheffer, Roberta G, Major, Marcie, Popovich, John, Iannuzzi, Michael C

“…The pathogenesis of sarcoidosis, a multisystem granulomatous disorder, is mediated through immunoregulatory pathways. While sarcoidosis clusters in families,…”
Get full text

Population Dynamics and Community Composition of Ammonia Oxidizers in Salt Marshes after the Deepwater Horizon Oil Spill by Bernhard, Anne E, Sheffer, Roberta, Giblin, Anne E, Marton, John M, Roberts, Brian J

“…The recent oil spill in the Gulf of Mexico had significant effects on microbial communities in the Gulf, but impacts on nitrifying communities in adjacent salt…”
Get full text

Binding of heparin to human high molecular weight kininogen by Bjoerk, Ingemar, Olson, Steven T, Sheffer, Roberta G, Shore, Joseph D

“…The binding of heparin to high molecular weight kininogen (H-kininogen) was analyzed by the effect of kininogen in decreasing the heparin-induced enhancement…”
Get full text

Microbial diversity in Cenozoic sediments recovered from the Lomonosov Ridge in the Central Arctic Basin by Forschner, Stephanie R, Sheffer, Roberta, Rowley, David C, Smith, David C

“…The current understanding of microbes inhabiting deeply buried marine sediments is based largely on samples collected from continental shelves in tropical and…”
Get full text

Antibiotic Bisanthraquinones Produced by a Streptomycete Isolated from a Cyanobacterium Associated with Ecteinascidia turbinata by SOCHA, Aaron M., GARCIA, Dioscaris, SHEFFER, Roberta, ROWLEY, David C.

“…Chemical studies of a streptomycete isolated from a cyanobacterium associated with the tropical tunicate Ecteinascidia turbinata led to the bioassay-guided…”
Get full text

Role of the antithrombin-binding pentasaccharide in heparin acceleration of antithrombin-proteinase reactions. Resolution of the antithrombin conformational change contribution to heparin rate enhancement by OLSON, S. T, BJÖRK, I, SHEFFER, R, CRAIG, P. A, SHORE, J. D, CHOAY, J

“…The synthetic antithrombin-binding heparin pentasaccharide and a full-length heparin of approximately 26 saccharides containing this specific sequence have…”
Get full text

Antibiotic Bisanthraquinones Produced by a Streptomycete Isolated from a Cyanobacterium Associated with Ecteinascidia t urbinata by Socha, Aaron M, Garcia, Dioscaris, Sheffer, Roberta, Rowley, David C

“…Chemical studies of a streptomycete isolated from a cyanobacterium associated with the tropical tunicate Ecteinascidia turbinata led to the bioassay-guided…”
Get full text

Angiotensin-converting enzyme gene polymorphism an risk of sarcoidosis by MALIARIK, M. J, RYBICKI, B. A, MALVITZ, E, SHEFFER, R. G, MAJOR, M, POPOVICH, J. JR, IANNUZZI, M. C

“…The angiotensin-converting enzyme (ACE) has been implicated in the pathophysiology of sarcoidosis. Serum ACE levels in normal and sarcoidosis patients are…”
Get full text

Analysis of HLA-DPB1 polymorphisms in African-Americans with sarcoidosis by MALIARIK, M. J, KANG MEI CHEN, MAJOR, M. L, SHEFFER, R. G, POPOVICH, J. JR, RYBICKI, B. A, IANNUZZI, M. C

“…Several studies have found weak associations between certain human leukocyte antigen (HLA) alleles and sarcoidosis, but none have been conclusive. Glutamic…”
Get full text

The distribution of long range admixture linkage disequilibrium in an African-American population by Rybicki, Benjamin A, Iyengar, Sudha K, Harris, Trent, Liptak, Rachel, Elston, Robert C, Sheffer, Roberta, Chen, Kang Mei, Major, Marcie, Maliarik, Mary J, Iannuzzi, Michael C

“…To better understand the effect of admixture on long range linkage disequilibrium (LD), we characterized extended LD in gene-rich regions of an…”
Get more information

The Blau syndrome gene is not a major risk factor for sarcoidosis by Rybicki, B A, Maliarik, M J, Bock, C H, Elston, R C, Baughman, R P, Kimani, A P, Sheffer, R G, Chen, K M, Major, M, Popovich, Jr, J, Iannuzzi, M C

“…A genetic predisposition to sarcoidosis has long been postulated, although no specific susceptibility genes are known. Candidate genes for the two…”
Get more information

High molecular weight kininogen potentiates the heparin-accelerated inhibition of plasma kallikrein by antithrombin: Role for antithrombin in the regulation of kallikrein by Olson, Steven T, Sheffer, Roberta, Francis, Ann Marie

“…The effects of previously characterized interactions of high molecular weight kininogen (H-kininogen) with plasma kallikrein and with heparin on the regulation…”
Get full text

Quantitative evaluation of solution equilibrium binding interactions by affinity partitioning: application to specific and nonspecific protein-heparin interactions by Olson, S T, Bock, P E, Sheffer, R

“…A variation of the quantitative affinity chromatography (QAC) method of Winzor, Chaiken, and co-workers for the analysis of protein-ligand interactions has…”
Get more information

Parallel mechanisms of high molecular weight kininogen action as a cofactor in kallikrein inactivation and prekallikrein activation reactions by Olson, Steven T, Francis, Ann Marie, Sheffer, Roberta, Choay, Jean

“…The mechanism by which high molecular weight kininogen (H-kininogen) potentiates the heparin-accelerated inhibition of plasma kallikrein by antithrombin…”
Get full text