Search Results - "Sheen, I Shyan"

Incidence and predictors of hepatitis B surface antigen seroclearance after cessation of nucleos(t)ide analogue therapy in hepatitis B e antigen–negative chronic hepatitis B by Jeng, Wen‐Juei, Chen, Yi‐Cheng, Chien, Rong‐Nan, Sheen, I‐Shyan, Liaw, Yun‐Fan

“…Hepatitis B surface antigen (HBsAg) loss is a rare event during nucleos(t)ide analogue (Nuc) therapy. Limited data suggest that stopping Nuc therapy may…”
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Off‐therapy durability of response to entecavir therapy in hepatitis B e antigen‐negative chronic hepatitis B patients by Jeng, Wen‐Juei, Sheen, I‐Shyan, Chen, Yi‐Cheng, Hsu, Chao‐Wei, Chien, Rong‐Nan, Chu, Chia‐Ming, Liaw, Yun‐Fan

“…The optimal duration of nucelos(t)ide analog (Nuc) treatment in hepatitis B e antigen (HBeAg)‐negative patients with chronic hepatitis B virus (HBV) infection…”
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The Role of Smoothened in Cancer by Jeng, Kuo-Shyang, Sheen, I-Shyan, Leu, Chuen-Miin, Tseng, Ping-Hui, Chang, Chiung-Fang

“…Smoothened (SMO) belongs to the Hedgehog (HH) signaling pathway, which regulates cell growth, migration, invasion and stem cells in cancer. The HH signaling…”
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Tenofovir disoproxil fumarate (TDF), emtricitabine/TDF, and entecavir in patients with decompensated chronic hepatitis B liver disease by Liaw, Yun‐Fan, Sheen, I‐Shyan, Lee, Chuan‐Mo, Akarca, Ulus Salih, Papatheodoridis, George V., Suet‐Hing Wong, Florence, Chang, Ting‐Tsung, Horban, Andrzej, Wang, Chia, Kwan, Peter, Buti, Maria, Prieto, Martin, Berg, Thomas, Kitrinos, Kathryn, Peschell, Ken, Mondou, Elsa, Frederick, David, Rousseau, Franck, Schiff, Eugene R.

“…Data are limited on the safety and effectiveness of oral antivirals other than lamivudine and adefovir dipivoxil for treatment of chronic hepatitis B (CHB) in…”
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Innate‐like bystander‐activated CD38+HLA‐DR+CD8+T cells play a pathogenic role in patients with chronic hepatitis C by Huang, Chien‐Hao, Fan, Jian‐He, Jeng, Wen‐Juei, Chang, Shu‐Ting, Yang, Chan‐Keng, Teng, Wei, Wu, Tsung‐Han, Hsieh, Yi‐Chung, Chen, Wei‐Ting, Chen, Yi‐Cheng, Sheen, I‐Shyan, Lin, Yung‐Chang, Lin, Chun‐Yen

“…Background and Aims HCV‐specific T cells are few and exhausted in patients with chronic hepatitis C (CHC). Whether these T cells are responsible for the liver…”
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Long‐term outcome of hepatitis B e antigen–negative hepatitis B surface antigen carriers in relation to changes of alanine aminotransferase levels over time by Tai, Dar‐In, Lin, Shi‐Ming, Sheen, I‐Shyan, Chu, Chia‐Ming, Lin, Deng‐Yn, Liaw, Yun‐Fan

“…The baseline alanine aminotransferase (ALT) level was reported to have prognostic value in chronic hepatitis B virus (HBV) infection, during which ALT may…”
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Sonic Hedgehog signaling pathway as a potential target to inhibit the progression of hepatocellular carcinoma (Review) by Jeng, Kuo-Shyang, Jeng, Chi-Juei, Jeng, Wen-Juei, Sheen, I-Shyan, Li, Shih-Yun, Leu, Chuen-Miin, Tsay, Yeou-Guang, Chang, Chiung-Fang

“…Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-associated mortality worldwide. Hepatocarcinogenesis involves numerous interlinked…”
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The Role of Endoglin in Hepatocellular Carcinoma by Jeng, Kuo-Shyang, Sheen, I-Shyan, Lin, Shu-Sheng, Leu, Chuen-Miin, Chang, Chiung-Fang

“…Endoglin (CD105) is a type-1 integral transmembrane glycoprotein and coreceptor for transforming growth factor-β (TGF-β) ligands. The endoglin/TGF-β signaling…”
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Ledipasvir/Sofosbuvir for Patients Coinfected With Chronic Hepatitis C and Hepatitis B in Taiwan: Follow-up at 108 Weeks Posttreatment by Liu, Chun Jen, Sheen, I Shyan, Chen, Chi Yi, Chuang, Wan Long, Wang, Horng Yuan, Tseng, Kuo Chih, Chang, Ting Tsung, Yang, Jenny, Massetto, Benedetta, Suri, Vithika, Camus, Gregory, Jiang, Deyuan, Zhang, Fangqiu, Gaggar, Anuj, Hu, Tsung Hui, Hsu, Yu Chun, Lo, Gin Ho, Chu, Chi Jen, Chen, Jyh Jou, Peng, Cheng Yuan, Chien, Rong Nan, Chen, Pei Jer

“…For patients coinfected with hepatitis C virus (HCV) and hepatitis B virus (HBV), HCV treatment with direct-acting antivirals can lead to HBV reactivation. We…”
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Comparing Predictability of Non-invasive Tools for Hepatocellular Carcinoma in Treated Chronic Hepatitis C Patients by Liu, Yen-Chun, Cheng, Ya-Ting, Chen, Yi-Cheng, Hsieh, Yi-Chung, Jeng, Wen-Juei, Lin, Chun-Yen, Chien, Rong-Nan, Tai, Dar-In, Sheen, I.-Shyan

“…Background Non-invasive tools including liver stiffness measurement (LSM) or FIB-4, assessed before or after direct acting antivirals (DAA), have been…”
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Evolution of renal function under direct‐acting antivirals treatment for chronic hepatitis C: A real‐world experience by Tsai, Ming‐Chao, Lin, Chun‐Yen, Hung, Chao‐Hung, Lu, Sheng‐Nan, Tung, Shui‐Yi, Chien, Rong‐Nan, Lin, Chih‐Lang, Wang, Jing‐Houng, Chien‐Hung, Chen, Chang, Kuo‐Chin, Hu, Tsung‐Hui, Sheen, I‐Shyan

“…Renal toxicity of direct‐acting antivirals (DAAs) in chronic hepatitis C (CHC) patients has not been well‐characterized. The aim of this study was to assess…”
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Interferon therapy in HBeAg positive chronic hepatitis reduces progression to cirrhosis and hepatocellular carcinoma by Lin, Shi-Ming, Yu, Ming-Lung, Lee, Chuan-Mo, Chien, Rong-Nan, Sheen, I-Shyan, Chu, Chia-Ming, Liaw, Yun-Fan

“…Background/Aims The long-term outcomes of interferon-alpha (IFN-α) therapy in hepatitis B e antigen (HBeAg) seropositive patients remain controversial. This…”
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Subsequent locoregional therapy prolongs survival in progressive hepatocellular carcinoma patients under lenvatinib treatment by Lin, Po-Ting, Teng, Wei, Jeng, Wen-Juei, Lin, Chen-Chun, Lin, Chun-Yen, Lin, Shi-Ming, Sheen, I-Shyan

“…Locoregional therapy and multi-kinase inhibitor agent have been the backbone of treatment for hepatocellular carcinoma (HCC) patients. However, the effect of…”
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Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B by Hsu, Yao-Shih, Chien, Rong-Nan, Yeh, Chau-Ting, Sheen, I-Shyan, Chiou, Hung-Yi, Chu, Chia-Ming, Liaw, Yun-Fan

“…During the course of chronic hepatitis B virus (HBV) infection, hepatitis B e antigen (HBeAg) seroconversion to its antibody (anti-HBe) often coincides with…”
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Ritonavir-boosted danoprevir plus peginterferon alfa-2a and ribavirin in Asian chronic hepatitis C patients with or without cirrhosis by Kao, Jia-Horng, Tung, Shui-Yi, Lee, Younjae, Thongsawat, Satawat, Tanwandee, Tawesak, Sheen, I.-Shyan, Wu, Jinzi J., Li, Hui, Brennan, Barbara J., Zhou, Julian, Le Pogam, Sophie, Najera, Isabel, Thommes, James A., Hill, George

“…Background and Aim Chronic hepatitis C is an important public health problem in Asia. We evaluated the safety, efficacy, and pharmacokinetics of fixed‐dose…”
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Reappraisal of the Roles of the Sonic Hedgehog Signaling Pathway in Hepatocellular Carcinoma by Jeng, Kuo-Shyang, Chang, Chiung-Fang, Tsang, Yuk-Ming, Sheen, I-Shyan, Jeng, Chi-Juei

“…HCC remains one of the leading causes of cancer-related death globally. The main challenges in treatments of hepatocellular carcinoma (HCC) primarily arise…”
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Soluble form of CTLA‐4 is a good predictor for tumor recurrence after radiofrequency ablation in hepatocellular carcinoma patients by Teng, Wei, Jeng, Wen‐Juei, Chen, Wei‐Ting, Lin, Chen‐Chun, Lin, Chun‐Yen, Lin, Shi‐Ming, Sheen, I‐Shyan

“…Background A soluble form of cytotoxic‐T‐lymphocyte‐antigen‐4 (sCTLA‐4) is a prognostic biomarker for several cancers but remains unclear in HCC patients. The…”
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Serial changes of renal function after directly acting antivirals treatment for chronic hepatitis C: A 1-year follow-up study after treatment by Chiu, Shao-Ming, Tsai, Ming-Chao, Lin, Chun-Yen, Chen, Chien-Hung, Lu, Sheng-Nan, Hung, Chao-Hung, Sheen, I-Shyan, Chien, Rong-Nan, Lin, Chih-Lang, Hu, Tsung-Hui, Cheng, Yu-Fan, Chen, Chao-Long

“…Our preliminary data showed a slight decrease of estimated glomerular filtration rate (eGFR) after direct-acting antivirals (DAAs) treatment in chronic…”
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In HCV-related liver cirrhosis, local pulse wave velocity increases and in decompensated patients correlates with poorer survival by Huang, Chien-Hao, Wu, Lung-Sheng, Jeng, Wen-Juei, Cheng, Yu-Fu, Ko, Yu-Shien, Sheen, I-Shyan, Lin, Chun-Yen

“…Cirrhotic cardiomyopathy (CCM) refers to cardiac dysfunction in patients with liver cirrhosis, in the absence of other known cardiac disease. Control group and…”
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The 2020 Nobel Prize in medicine for the discovery of hepatitis C virus: An epic saga of the fight against a troublesome virus by Lin, Chun-Yen, Chien, Rong-Nan, Sheen, I-Shyan

“…Chronic hepatitis C, which is caused by the hepatitis C virus, represents a substantial health threat to humans and causes approximately 700,000 deaths each…”
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