Search Results - "Sheehan, Penelope"
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Maternal Thyroid Disease and Preterm Birth: Systematic Review and Meta-Analysis
Published in The journal of clinical endocrinology and metabolism (01-11-2015)“…Context: Thyroid disease in pregnancy is increasing with rising average maternal ages in developed countries. The evidence for an association between preterm…”
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Reductions in stillbirths and preterm birth in COVID-19–vaccinated women: a multicenter cohort study of vaccination uptake and perinatal outcomes
Published in American journal of obstetrics and gynecology (01-05-2023)“…COVID-19 infection in pregnancy is associated with a higher risk of progression to severe disease, but vaccine uptake by pregnant women is hindered by…”
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Increase in preterm stillbirths in association with reduction in iatrogenic preterm births during COVID-19 lockdown in Australia: a multicenter cohort study
Published in American journal of obstetrics and gynecology (01-09-2022)“…The COVID-19 pandemic has been associated with a worsening of perinatal outcomes in many regions around the world. Melbourne, Australia, had one of the longest…”
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NO placental inflammation
Published in The Journal of physiology (01-06-2020)Get full text
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Cervical length surveillance for predicting spontaneous preterm birth in women with uterine anomalies: A cohort study
Published in Acta obstetricia et gynecologica Scandinavica (01-11-2020)“…Uterine anomalies occur in an estimated 5% of women and have been shown to confer a higher risk of spontaneous preterm birth (SPTB). A sonographically short…”
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Assessment of Placental Cortisol Pathway Gene Expression in Term Pregnant Women with Anxiety
Published in Neuropsychobiology (2019)“…The aim of this study was to expand on this field of work by examining, within a cohort of pregnant women with diagnosed clinical anxiety, the mRNA expression…”
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Trends in maternal body mass index, macrosomia and caesarean section in first-time mothers during the pandemic: a multicentre retrospective cohort study of 12 Melbourne public hospitals
Published in BMC pregnancy and childbirth (28-10-2024)“…To compare specific perinatal outcomes in nulliparas with a singleton infant in cephalic presentation at term, with and without exposure to the COVID-19…”
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Vessel remodelling, pregnancy hormones and extravillous trophoblast function
Published in Molecular and cellular endocrinology (26-02-2012)“…► Vessel remodelling in early human pregnancy requires trophoblast invasion. ► hCG, P4 and E2 are all found at high concentrations at the maternal–foetal…”
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Identification of biochemical biomarkers associated with premature cervical shortening in high-risk, asymptomatic pregnant women: a retrospective data analysis
Published in Journal of obstetrics and gynaecology (01-12-2023)“…Reliably predicting spontaneous preterm birth remains challenging, therefore it persists as a major contributor to perinatal morbidity and mortality. The use…”
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Reduction in spontaneous and iatrogenic preterm births in twin pregnancies during COVID-19 lockdown in Melbourne, Australia: a multicenter cohort study
Published in BMC pregnancy and childbirth (11-12-2023)“…Melbourne, Australia, recorded one of the longest and most stringent pandemic lockdowns in 2020, which was associated with an increase in preterm stillbirths…”
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Setting the pace for labour
Published in The Journal of physiology (01-07-2018)Get full text
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Analysis of epigenetic changes in survivors of preterm birth reveals the effect of gestational age and evidence for a long term legacy
Published in Genome medicine (18-10-2013)“…Preterm birth confers a high risk of adverse long term health outcomes for survivors, yet the underlying molecular mechanisms are unclear. We hypothesized that…”
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Diminished hERG K+ channel activity facilitates strong human labour contractions but is dysregulated in obese women
Published in Nature communications (17-06-2014)“…Human ether-a-go-go-related gene (hERG) potassium channels determine cardiac action potential and contraction duration. Human uterine contractions are…”
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The addition of fetal scalp blood lactate measurement as an adjunct to cardiotocography to reduce caesarean sections during labour: The Flamingo randomised controlled trial
Published in Australian & New Zealand journal of obstetrics & gynaecology (01-10-2021)“…Background Fetal scalp blood sampling for lactate measurement (FBSLM) is sometimes used to assist in identification of the need for expedited birth in the…”
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Collaborative maternity and newborn dashboard (CoMaND) for the COVID-19 pandemic: a protocol for timely, adaptive monitoring of perinatal outcomes in Melbourne, Australia
Published in BMJ open (23-11-2021)“…BackgroundThe COVID-19 pandemic has resulted in a range of unprecedented disruptions to maternity care with documented impacts on perinatal outcomes such as…”
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Rescue Adjuvant Vaginal Progesterone May Improve Outcomes in Cervical Cerclage Failure
Published in Geburtshilfe und Frauenheilkunde (01-08-2018)“…Abstract Introduction Aim of the study was to evaluate the effect of rescue adjuvant vaginal progesterone in women with ongoing, transvaginal ultrasound…”
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Changes in myometrial expression of progesterone receptor membrane components 1 and 2 are associated with human parturition at term
Published in Reproduction fertility and development (01-01-2016)“…While the exact mechanism of human parturition remains unknown, functional progesterone withdrawal is believed to play a key regulatory role. Progesterone…”
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Mother Nature versus Father Time
Published in The Journal of physiology (15-03-2017)Get full text
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Subclinical hypothyroidism during pregnancy: the Melbourne public hospitals consensus
Published in Internal medicine journal (01-08-2019)“…Background Interest in potential adverse outcomes associated with maternal subclinical hypothyroidism (normal free T4, elevated thyroid‐stimulating hormone…”
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Factors associated with spontaneous preterm birth risk assessed by transvaginal ultrasound following cervical cerclage
Published in Australian & New Zealand journal of obstetrics & gynaecology (01-08-2015)“…Objective To determine the predictive value of various cervical length measurements postcerclage for the outcome of preterm birth following both elective and…”
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