Search Results - "Sheehan, F"
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Miro proteins coordinate microtubule‐ and actin‐dependent mitochondrial transport and distribution
Published in The EMBO journal (01-02-2018)“…In the current model of mitochondrial trafficking, Miro1 and Miro2 Rho‐GTPases regulate mitochondrial transport along microtubules by linking mitochondria to…”
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2
Slow slip near the trench at the Hikurangi subduction zone, New Zealand
Published in Science (American Association for the Advancement of Science) (06-05-2016)“…The range of fault slip behaviors near the trench at subduction plate boundaries is critical to know, as this is where the world's largest, most damaging…”
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3
Persistent LCMV Infection Is Controlled by Blockade of Type I Interferon Signaling
Published in Science (American Association for the Advancement of Science) (12-04-2013)“…During persistent viral infections, chronic immune activation, negative immune regulator expression, an elevated interferon signature, and lymphoid tissue…”
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4
Seismic Azimuthal Anisotropy Beneath the Alaska Subduction Zone
Published in Geophysical research letters (28-07-2024)“…We estimate depth‐dependent azimuthal anisotropy and shear wave velocity structure beneath the Alaska subduction zone by the inversion of a new Rayleigh wave…”
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5
Temporal Relationship of Slow Slip Events and Microearthquake Seismicity: Insights From Earthquake Automatic Detections in the Northern Hikurangi Margin, Aotearoa New Zealand
Published in Geochemistry, geophysics, geosystems : G3 (01-03-2023)“…Slow slip events in the northern Hikurangi margin of Aotearoa New Zealand occur every 18–24 months and last for several weeks before returning to average…”
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6
The right ventricle: anatomy, physiology and clinical imaging
Published in Heart (British Cardiac Society) (01-11-2008)Get more information
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7
Population impact of lung cancer screening in the United States: Projections from a microsimulation model
Published in PLoS medicine (07-02-2018)“…Previous simulation studies estimating the impacts of lung cancer screening have ignored the changes in smoking prevalence over time in the United States. Our…”
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Miro1 Regulates Activity-Driven Positioning of Mitochondria within Astrocytic Processes Apposed to Synapses to Regulate Intracellular Calcium Signaling
Published in The Journal of neuroscience (02-12-2015)“…It is fast emerging that maintaining mitochondrial function is important for regulating astrocyte function, although the specific mechanisms that govern…”
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NMDA Receptor Activation Underlies the Loss of Spinal Dorsal Horn Neurons and the Transition to Persistent Pain after Peripheral Nerve Injury
Published in Cell reports (Cambridge) (29-05-2018)“…Peripheral nerve lesions provoke apoptosis in the dorsal horn of the spinal cord. The cause of cell death, the involvement of neurons, and the relevance for…”
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10
Type I IFN Contributes to NK Cell Homeostasis, Activation, and Antitumor Function
Published in Journal of Immunology (15-06-2007)“…This study demonstrates that type I IFNs are an early and critical regulator of NK cell numbers, activation, and antitumor activity. Using both IFNAR1- and…”
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An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABAA Receptors
Published in Cell reports (Cambridge) (03-10-2017)“…Inhibitory synaptic transmission requires the targeting and stabilization of GABAA receptors (GABAARs) at synapses. The mechanisms responsible remain poorly…”
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An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABA A Receptors
Published in Cell reports (Cambridge) (03-10-2017)“…Inhibitory synaptic transmission requires the targeting and stabilization of GABA receptors (GABA Rs) at synapses. The mechanisms responsible remain poorly…”
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13
Neuronal activity mediated regulation of glutamate transporter GLT-1 surface diffusion in rat astrocytes in dissociated and slice cultures
Published in Glia (01-07-2016)“…The astrocytic GLT‐1 (or EAAT2) is the major glutamate transporter for clearing synaptic glutamate. While the diffusion dynamics of neurotransmitter receptors…”
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14
The autism and schizophrenia associated gene CYFIP1 is critical for the maintenance of dendritic complexity and the stabilization of mature spines
Published in Translational psychiatry (25-03-2014)“…Copy number variation (CNV) at the 15q11.2 region has been identified as a significant risk locus for neurological and neuropsychiatric conditions such as…”
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15
Sources and Pathways of Glacial Meltwater in the Bellingshausen Sea, Antarctica
Published in Geophysical research letters (28-07-2023)“…Meltwater content and pathways determine the impact of Antarctica's melting ice shelves on ocean circulation and climate. Using ocean glider observations, we…”
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16
Tsunami Data Assimilation Without a Dense Observation Network
Published in Geophysical research letters (28-02-2019)“…The tsunami data assimilation method enables tsunami forecasting directly from observations, without the need of estimating tsunami sources. However, it…”
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17
Lung cancer costs by treatment strategy and phase of care among patients enrolled in Medicare
Published in Cancer medicine (Malden, MA) (01-01-2019)“…Background We studied trends in lung cancer treatment cost over time by phase of care, treatment strategy, age, stage at diagnosis, and histology. Methods…”
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Estimate of tsunami source using optimized unit sources and including dispersion effects during tsunami propagation: The 2012 Haida Gwaii earthquake
Published in Geophysical research letters (28-09-2016)“…We apply a genetic algorithm to find the optimized unit sources using dispersive tsunami synthetics to estimate the tsunami source of the 2012 Haida Gwaii…”
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Earthquakes and Tremor Linked to Seamount Subduction During Shallow Slow Slip at the Hikurangi Margin, New Zealand
Published in Journal of geophysical research. Solid earth (01-08-2018)“…Shallow slow slip events have been well documented offshore Gisborne at the northern Hikurangi subduction margin, New Zealand, and are associated with tectonic…”
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A simulation study of the effect of lung cancer screening in China, Japan, Singapore, and South Korea
Published in PloS one (30-07-2019)“…More than 50% of the world's lung cancer cases occur in Asia and more than 20% of cancer deaths in Asia are attributable to lung cancer. The U.S. National Lung…”
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