Search Results - "Sheean, G."

The pathophysiology of spasticity by Sheean, G.

“…Spasticity is only one of several components of the upper motor neurone (UMN) syndrome, known collectively as the `positive' phenomena, that are characterized…”
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Botulinum toxin assessment, intervention and after-care for upper limb hypertonicity in adults: international consensus statement by Sheean, G., Lannin, N. A., Turner-Stokes, L., Rawicki, B., Snow, B. J.

“…Upper limb spasticity affecting elbow, wrist, and finger flexors can be safely and effectively reduced with injections of botulinum toxin type‐A (BoNT‐A). It…”
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International consensus statement for the use of botulinum toxin treatment in adults and children with neurological impairments - introduction by Esquenazi, A., Novak, I., Sheean, G., Singer, B. J., Ward, A. B.

“…Botulinum neurotoxin (BoNT) is most commonly used to reduce focal over‐activity in skeletal muscle, although newer indications such as management of drooling,…”
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An electrophysiological study of the mechanism of fatigue in multiple sclerosis by SHEEAN, G. L, MURRAY, N. M. F, ROTHWELL, J. C, MILLER, D. H, THOMPSON, A. J

“…Fatigue is a common and disabling symptom in multiple sclerosis but is poorly understood. We investigated 'physiological' fatigue in 21 patients with multiple…”
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Botulinum toxin assessment, intervention and aftercare for paediatric and adult niche indications including pain: international consensus statement by Rawicki, B., Sheean, G., Fung, V. S. C., Goldsmith, S., Morgan, C., Novak, I.

“…Evidence is emerging for the use of botulinum neurotoxin type‐A (BoNT‐A) for niche indications including pain independent of spasticity. Pain indications such…”
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Changes in the balance between motor cortical excitation and inhibition in focal, task specific dystonia by Ridding, M C, Sheean, G, Rothwell, J C, Inzelberg, R, Kujirai, T

“…Transcranial magnetic stimulation has been used in a double pulse paradigm to investigate the excitability of intrinsic motor cortical circuits in 15 patients…”
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The external anal sphincter operates at short sarcomere length in humans by Mittal, R. K., Sheean, G., Padda, B. S., Lieber, R., Raj Rajasekaran, M.

“…Background  The length at which a muscle/sarcomere operates in vivo (operational length) and the length at which it generates maximal stress (optimal length)…”
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Botulinum treatment of spasticity: why is it so difficult to show a functional benefit? by Sheean, G L

“…Clinical experience seems to indicate that botulinum toxin injections can, in selected patients with upper motor neurone syndrome, reduce spasticity and…”
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Evaluating the role of botulinum toxin in the management of focal hypertonia in adults by Richardson, Davina, Sheean, Geoff, Werring, David, Desai, Margi, Edwards, Susan, Greenwood, Richard, Thompson, Alan

“…OBJECTIVES To investigate the effects of EMG guided botulinum toxin (BTX-A) on impairment and focal disability in adults presenting with focal hypertonia…”
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Abnormal motor unit synchronization of antagonist muscles underlies pathological co-contraction in upper limb dystonia by FARMER, S. F, SHEEAN, G. L, MAYSTON, M. J, ROTHWELL, J. C, MARSDEN, C. D, CONWAY, B. A, HALLIDAY, D. M, ROSENBERG, J. R, STEPHENS, J. A

“…The aim of this study was to examine the pathophysiological mechanisms underlying co-contraction in patients with dystonia (n = 6) and writer's cramp (n = 5)…”
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Anchor universities as leaders in the well-being movement: lessons learned from the University of California Healthy Campus Network & pandemic by Slusser, Wendelin, Schmidt, L, Imbery, C, Watson, T, Moin, T, Chobdee, J, Alas, S, Ezenwugo, S, Sheean-Remotto, G

“…The University of California (UC) Healthy Campus Network (HCN) is a robust network of diverse coalitions across 10 UC campuses, 5 UC teaching hospitals, and UC…”
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Botulinum toxin does not reverse the cortical dysfunction associated with writer's cramp a PET study by CEBALLOS-BAUMANN, A. O, SHEEAN, G, PASSINGHAM, R. E, MARSDEN, C. D, BROOKS, D. J

“…Previous H2(15)O PET activation studies on patients with idiopathic torsion dystonia (ITD) have shown overactive striatum and frontal accessory areas and…”
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An open-labelled clinical and electrophysiological study of 3,4 diaminopyridine in the treatment of fatigue in multiple sclerosis by SHEEAN, G. L, MURRAY, N. M. F, ROTHWELL, J. C, MILLER, D. H, THOMPSON, A. J

“…We studied the electrophysiological parameters of motor performance in eight patients with multiple sclerosis and troublesome fatigue, before and after…”
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Further studies using higher doses of botulinum toxin type F for torticollis resistant to botulinum toxin type A by Houser, M K, Sheean, G L, Lees, A J

“…OBJECTIVE A previous study of botulinum toxin type F (BTX-F) treatment for torticollis had shown a dose of 520 MU to be effective, but for a much shorter…”
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Complete remission induced by rituximab in refractory, seronegative, muscle-specific, kinase-positive myasthenia gravis by Baek, William S, Bashey, Asad, Sheean, Geoffrey L

“…Rituximab depletes B cells by binding to the CD20 molecule and initiating complement-dependent cytolysis or antibody-dependent cell-mediated cytotoxicity. 1…”
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Pain and remote weakness in limbs injected with botulinum toxin A for writer's cramp by Sheean, G L, Murray, N M, Marsden, C D

“…We describe two cases of a syndrome resembling neuralgic amyotrophy that occurred in limbs injected with botulinum toxin for writer's cramp. In both cases, one…”
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OC34.07: Measurement of muscles of anal canal using 3D ultrasound by Pretorius, D., Guaderrama, N. M., Liu, J., Nager, C. W., Sheean, G., Mittal, R. K.

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Botulinum toxin F in the treatment of torticollis clinically resistant to botulinum toxin A by Sheean, G L, Lees, A J

“…Two reports have shown a Japanese preparation of botulinum toxin type F (BTX-F) to be an effective alternative for patients with torticollis who develop…”
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Botulinum toxin treatment of adult spasticity : A benefit-risk assessment by SHEEAN, Geoffrey

“…Injections of botulinum toxin have revolutionised the treatment of focal spasticity. Before their advent, the medical treatment for focal spasticity involved…”
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Botulinum toxin should be first-line treatment for poststroke spasticity by Sheean, Geoffrey

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