Search Results - "Shearwood, A M"

Expression of secreted frizzled-related protein 4 (SFRP4) in primary serous ovarian tumours by Drake, J, Shearwood, A M, White, J, Friis, R, Zeps, N, Charles, A, Dharmarajan, A

“…Serous ovarian cancer is the most prevalent type of ovarian cancer. The majority of women present at an advanced stage and patient survival is poor. Resistance…”
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LRPPRC-mediated folding of the mitochondrial transcriptome by Siira, Stefan J., Spåhr, Henrik, Shearwood, Anne-Marie J., Ruzzenente, Benedetta, Larsson, Nils-Göran, Rackham, Oliver, Filipovska, Aleksandra

“…The expression of the compact mammalian mitochondrial genome requires transcription, RNA processing, translation and RNA decay, much like the more complex…”
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Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly by Rackham, Oliver, Busch, Jakob D., Matic, Stanka, Siira, Stefan J., Kuznetsova, Irina, Atanassov, Ilian, Ermer, Judith A., Shearwood, Anne-Marie J., Richman, Tara R., Stewart, James B., Mourier, Arnaud, Milenkovic, Dusanka, Larsson, Nils-Göran, Filipovska, Aleksandra

“…The regulation of mitochondrial RNA processing and its importance for ribosome biogenesis and energy metabolism are not clear. We generated conditional…”
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Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors by Rackham, Oliver, Shearwood, Anne-Marie J., Thyer, Ross, McNamara, Elyshia, Davies, Stefan M.K., Callus, Bernard A., Miranda-Vizuete, Antonio, Berners-Price, Susan J., Cheng, Qing, Arnér, Elias S.J., Filipovska, Aleksandra

“…The cytosolic and mitochondrial thioredoxin reductases (TrxR1 and TrxR2) and thioredoxins (Trx1 and Trx2) are key components of the mammalian thioredoxin…”
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Expression of sFRP-4 and β-catenin in human colorectal carcinoma by Feng Han, Qian, Zhao, Wenying, Bentel, Jacky, Shearwood, Anne-Marie, Zeps, Nik, Joseph, David, Iacopetta, Barry, Dharmarajan, Arun

“…Alterations to the Wnt signalling pathway occur in the majority of colorectal cancers and result in abnormal accumulation of β-catenin. The secreted frizzled…”
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