Search Results - "Shearn, A"

Increased hepatocellular protein carbonylation in human end-stage alcoholic cirrhosis by Shearn, C.T., Orlicky, D.J., Saba, L.M., Shearn, A.H., Petersen, Dennis R.

“…Oxidative stress is a significant contributing factor in the pathogenesis of alcoholic liver disease (ALD). In the murine models of chronic alcohol…”
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The Drosophila trithorax group proteins BRM, ASH1 and ASH2 are subunits of distinct protein complexes by Papoulas, O, Beek, S J, Moseley, S L, McCallum, C M, Sarte, M, Shearn, A, Tamkun, J W

“…The trithorax group gene brahma (brm) encodes an activator of Drosophila homeotic genes that functions as the ATPase subunit of a large protein complex. To…”
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The ash-1, ash-2 and trithorax genes of Drosophila melanogaster are functionally related by Shearn, A

“…Mutations in the ash-1 and ash-2 genes of Drosophila melanogaster cause a wide variety of homeotic transformations that are similar to the transformations…”
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E(z): a polycomb group gene or a trithorax group gene? by LaJeunesse, D, Shearn, A

“…The products of the Polycomb group of genes are cooperatively involved in repressing expression of homeotic selector genes outside of their appropriate…”
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Growth, metastasis, and invasiveness of Drosophila tumors caused by mutations in specific tumor suppressor genes by Woodhouse, E, Hersperger, E, Shearn, A

“…More than 50 genes have been identified in Drosophila by loss-of-function mutations that lead to overgrowth of specific tissues. Loss-of-function mutations in…”
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Drosophila ash1 gene product, which is localized at specific sites on polytene chromosomes, contains a SET domain and a PHD finger by Tripoulas, N, LaJeunesse, D, Gildea, J, Shearn, A

“…The determined state of Drosophila imaginal discs depends on stable patterns of homeotic gene expression. The stability of these patterns requires the function…”
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Molecular Genetic Analysis of Drosophila ash2, a Member of the Trithorax Group Required for Imaginal Disc Pattern Formation by Adamson, A. L, Shearn, A

“…The ash2 gene is a member of the trithorax group of genes whose products function to maintain active transcription of homeotic selector genes. Mutations in…”
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Feasibility of a longitudinal statistical atlas model to study aortic growth in congenital heart disease by Sophocleous, F, Bone, A, Shearn, A I U, Nieves Velasco Forte, M, Bruse, J L, Caputo, M, Biglino, G

“…Abstract Background Studying anatomical shape progression over time is of utmost importance to refine our understanding of clinically relevant processes. These…”
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Germline transformation using a prune cDNA rescues prune/Killer of prune lethality and the prune eye color phenotype in Drosophila by Timmons, L, Shearn, A

“…Null mutations in the prune gene of Drosophila melanogaster result in prune eye color due to reductions in red pigment accumulation. When one copy of the awd…”
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Analysis of the lethal interaction between the prune and Killer of prune mutations of Drosophila by BIGGS, J, TRIPOULAS, N, HERSPERGER, E, DEAROLF, C, SHEARN, A

“…The third-chromosome mutation Killer of prune (K-pn) causes no phenotype by itself, but causes lethality in individuals homozygous for the nonlethal…”
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Molecular genetic analysis of Drosophila melanogaster gene absent, small or homeotic discs1 (ash 1) by Tripoulas, N.A, Hersperger, E, La Jeunesse, D, Shearn, A

“…The absent, small or homeotic discs1 gene (ash1) is one of the trithorax set of genes. Recessive loss of function mutations in ash1 cause homeotic…”
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Mutations in polycombeotic, a Drosophila polycomb-group gene, cause a wide range of maternal and zygotic phenotypes by Phillips, M.D. (The Johns Hopkins University, Baltimore, MD), Shearn, A

“…The polycomb-group genes, a set of genes characterized by mutations that cause similar phenotypes and dosage-dependent interactions, are required for the…”
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Imaginal discs can be recovered from cultured embryos mutant for the segment-polarity genes engrailed, naked and patched but not from wingless by Simcox, A A, Roberts, I J, Hersperger, E, Gribbin, M C, Shearn, A, Whittle, J R

“…Drosophila embryos homozygous for strong mutations in each of the segment-polarity genes wingless (wg), engrailed (en), naked (nkd) and patched (ptc) form a…”
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Rapid PCR for RNA differential display in a conventional heat block thermal cycler by Liu, L Z, Shearn, A

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ASH1, a Drosophila Trithorax Group Protein, Is Required for Methylation of Lysine 4 Residues on Histone H3 by Byrd, Kristin Nastase, Shearn, Allen

“…Covalent modifications of histone tails modulate gene expression via chromatin organization. As examples, methylation of lysine 9 residues of histone H3 (H3)…”
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Microparticles: Induced Exosomes in Cardiovascular Pathology255Exosomes from human cardiac-resident progenitor cells are more cardioprotective than exosomes from bone marrow mesenchymal stem cells via a pregnancy-associated plasma protein-a-dependent mechanism256The human pericardial fluid is enriched with cardiovascular-expressed microRNAs and exosomes with therapeutic potential257Circulating microparticles of healthy origins protect against atherosclerotic vascular disease via microRNA transfe by Barile, L, Beltrami, C, Georgescu, A, Cervio, E, Lionetti, V, Milano, G, Ciullo, A, Altomare, C, Torre, T, Demertzis, S, Moccetti, T, Mauri, P, Vassalli, G, Shantikumar, S, Laftha, A, Besnier, M, Rajakaruna, C, Shearn, A, Angelini, GD, Emanueli, C, Alexandru, N, Andrei, E, Dragan, E, Safciuc, F, Daraban, AM, Badila, E

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A Screen for New Trithorax Group Genes Identified little imaginal discs, the Drosophila melanogaster Homologue of Human Retinoblastoma Binding Protein 2 by Gildea, John J, Lopez, Rocio, Shearn, Allen

“…The proteins encoded by two groups of conserved genes, the Polycomb and trithorax groups, have been proposed to maintain, at the level of chromatin structure,…”
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Stress management and mutual support groups in rheumatoid arthritis by Shearn, M A, Fireman, B H

“…Stress management and mutual support groups are employed widely in chronic illness, although their efficacy has not been established. To determine the effect…”
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A deletion of the 3' end of the Drosophila melanogaster hsp70 gene increases stability of mutant mRNA during recovery from heat shock by Simcox, A A, Cheney, C M, Hoffman, E P, Shearn, A

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Effect of age and sex on the erythrocyte sedimentation rate by Shearn, M A, Kang, I Y

“…In a study designed to reevaluate standard normal values for the erythrocyte sedimentation rate (ESR) determined by modified Westergren method, we analyzed…”
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