Search Results - "She, Hongyun"

Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis by Cheng, Jason H, She, Hongyun, Han, Yuan-Ping, Wang, Jiaohong, Xiong, Shigang, Asahina, Kinji, Tsukamoto, Hidekazu

“…Activation of hepatic stellate cells (HSC), a key event in liver fibrosis, is caused by diminished adipogenic transcription. This study investigated whether…”
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Adipogenic Transcriptional Regulation of Hepatic Stellate Cells by She, Hongyun, Xiong, Shigang, Hazra, Saswati, Tsukamoto, Hidekazu

“…Hepatic stellate cells (HSC) undergo transdifferentiation (activation) from lipid-storing pericytes to myofibroblastic cells to participate in liver…”
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Clinically Relevant Progestins Regulate Neurogenic and Neuroprotective Responses in Vitro and in Vivo by Liu, Lifei, Zhao, Liqin, She, Hongyun, Chen, Shuhua, Wang, Jun Ming, Wong, Charisse, McClure, Kelsey, Sitruk-Ware, Regine, Brinton, Roberta Diaz

“…Previously, we demonstrated that progesterone (P4) promoted adult rat neural progenitor cell (rNPC) proliferation with concomitant regulation of cell-cycle…”
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Anti-adipogenic regulation underlies hepatic stellate cell transdifferentiation by Tsukamoto, Hidekazu, She, Hongyun, Hazra, Saswati, Cheng, Jason, Miyahara, Takeo

“…Cirrhosis is the most important consequence of alcoholic liver disease for which liver transplantation is the only treatment option available…”
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Steatohepatitis induced by intragastric overfeeding in mice by DENG, Qing-Gao, HONGYUN SHE, CHENG, Jason H, FRENCH, Samuel W, KOOP, Dennis R, SHIGANG XIONG, TSUKAMOTO, Hidekazu

“…Nonalcoholic steatohepatitis is prevalent among obese individuals with excessive caloric intake, insulin resistance, and type II diabetes. However, no animal…”
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Fat paradox of steatohepatitis by Tsukamoto, Hidekazu, She, Hongyun, Hazra, Saswati, Cheng, Jason, Wang, Jiaohong

“…Alcoholic and non‐alcoholic steatohepatitis (ASH and NASH) constitute two major types of chronic liver disease with worldwide prevalence and are histologically…”
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Nckβ Adapter Regulates Actin Polymerization in NIH 3T3 Fibroblasts in Response to Platelet-Derived Growth Factor bb by Chen, Min, She, Hongyun, Kim, Airie, Woodley, David T., Li, Wei

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Identification of Nck Family Genes, Chromosomal Localization, Expression, and Signaling Specificity by Chen, Min, She, Hongyun, Davis, Elizabeth M., Spicer, Catherine M., Kim, Leopold, Ren, Ruibao, Le Beau, Michelle M., Li, Wei

“…Already a dozen molecules share binding to the Src homology (SH) 3 domains of human Nck, an SH3-SH3-SH3-SH2 adapter protein. We reason that there may be…”
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Colony-stimulating factor-1 receptor utilizes multiple signaling pathways to induce cyclin D2 expression by Dey, A, She, H, Kim, L, Boruch, A, Guris, D L, Carlberg, K, Sebti, S M, Woodley, D T, Imamoto, A, Li, W

“…Colony-stimulating factor-1 (CSF-1) induces expression of immediate early gene, such as c-myc and c-fos and delayed early genes such as D-type cyclins (D1 and…”
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Iron Causes Interactions of TAK1, p21ras, and Phosphatidylinositol 3-Kinase in Caveolae to Activate IκB Kinase in Hepatic Macrophages by Chen, Li, Xiong, Shigang, She, Hongyun, Lin, Sharon W., Wang, Jiaohong, Tsukamoto, Hidekazu

“…We recently discovered a novel signaling phenomenon involving a rapid and transient rise in intracellular low molecular weight iron complex(es) in activation…”
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Signaling Role of Intracellular Iron in NF-κB Activation by Xiong, Shigang, She, Hongyun, Takeuchi, Heigo, Han, Bora, Engelhardt, John F., Barton, C.H., Zandi, Ebrahim, Giulivi, Cecilia, Tsukamoto, Hidekazu

“…Iron chelators inhibit endotoxin-induced NF- Kappa B activation in hepatic macrophages (HMs), suggesting a role for the intracellular chelatable pool of iron…”
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Hepatic macrophage iron aggravates experimental alcoholic steatohepatitis by Xiong, Shigang, She, Hongyun, Zhang, An-Sheng, Wang, Jiaohong, Mkrtchyan, Hasmik, Dynnyk, Alla, Gordeuk, Victor R, French, Samuel W, Enns, Caroline A, Tsukamoto, Hidekazu

“…One prime feature of alcoholic liver disease (ALD) is iron accumulation in hepatic macrophages/Kupffer cells (KC) associated with enhanced NF-kappaB…”
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Tumor necrosis factor-alpha inhibits peroxisome proliferator-activated receptor gamma activity at a posttranslational level in hepatic stellate cells by Sung, Chin K, She, Hongyun, Xiong, Shigang, Tsukamoto, Hidekazu

“…Diminished activity of peroxisome proliferator-activated receptor gamma (PPARgamma) is implicated in activation of hepatic stellate cells (HSC), a critical…”
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P2‐517: Preclinical development of allopregnanolone to restore cognitive function in a mouse model of Alzheimer's disease: transdermal and intranasal drug delivery by She, Hongyun, Chen, Shuhua, Wang, Junming, Bortolato, Marco, Singh, Chanpreet, Foy, Michael, Brinton, Roberta

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Preclinical development of allopregnanolone to restore cognitive function in a mouse model of Alzheimer's disease: transdermal and intranasal drug delivery by She, Hongyun, Chen, Shuhua, Wang, Junming, Bortolato, Marco, Singh, Chanpreet, Foy, Michael, Brinton, Roberta

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Iron-dependent activation of NF-κB in Kupffer cells: a priming mechanism for alcoholic liver disease by Xiong, Shigang, She, Hongyun, Sung, Chin K., Tsukamoto, Hidekazu

“…Alcoholic liver disease is associated with hepatic iron accumulation, and iron supplementation exacerbates alcoholic liver disease, suggesting the pathogenic…”
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Iron Causes Interactions of TAK1, p21ras, and Phosphatidylinositol 3-Kinase in Caveolae to Activate IκB Kinase in Hepatic Macrophages by Li Chen, Shigang Xiong, Hongyun She, Sharon W. Lin, Jiaohong Wang, Hidekazu Tsukamoto

“…We recently discovered a novel signaling phenomenon involving a rapid and transient rise in intracellular low molecular weight iron complex(es) in activation…”
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Iron causes interactions of TAK1, p21ras, and phosphatidylinositol 3-kinase in caveolae to activate IkappaB kinase in hepatic macrophages by Chen, Li, Xiong, Shigang, She, Hongyun, Lin, Sharon W, Wang, Jiaohong, Tsukamoto, Hidekazu

“…We recently discovered a novel signaling phenomenon involving a rapid and transient rise in intracellular low molecular weight iron complex(es) in activation…”
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1017 NRAMP1 mutation causes enhanced iron signaling for NF-KB activation and TNF-alpha expression in macrophages by Xiong, Shigang, She, Hongyun, Wang, Jiaohong, Tsukamoto, Hidekazu

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Iron-dependent activation of NF-kappaB in Kupffer cells: a priming mechanism for alcoholic liver disease by Xiong, Shigang, She, Hongyun, Sung, Chin K, Tsukamoto, Hidekazu

“…Alcoholic liver disease is associated with hepatic iron accumulation, and iron supplementation exacerbates alcoholic liver disease, suggesting the pathogenic…”
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