Search Results - "Shcherbinin, Dmitrii S."

Comprehensive analysis of structural and sequencing data reveals almost unconstrained chain pairing in TCRαβ complex by Shcherbinin, Dmitrii S, Belousov, Vlad A, Shugay, Mikhail

“…Antigen recognition by T-cells is guided by the T-cell receptor (TCR) heterodimer formed by α and β chains. A huge diversity of TCR sequences should be…”
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Large-scale template-based structural modeling of T-cell receptors with known antigen specificity reveals complementarity features by Shcherbinin, Dmitrii S., Karnaukhov, Vadim K., Zvyagin, Ivan V., Chudakov, Dmitriy M., Shugay, Mikhail

“…Introduction T-cell receptor (TCR) recognition of foreign peptides presented by the major histocompatibility complex (MHC) initiates the adaptive immune…”
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The mechanism of a one-substrate transketolase reaction by Solovjeva, Olga N, Kovina, Marina V, Zavialova, Maria G, Zgoda, Victor G, Shcherbinin, Dmitrii S, Kochetov, German A

“…Transketolase catalyzes the transfer of a glycolaldehyde residue from ketose (the donor substrate) to aldose (the acceptor substrate). In the absence of…”
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Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP by Tatarskiy, Victor V., Simonov, Yuriy P., Shcherbinin, Dmitrii S., Brechalov, Alexander V., Georgieva, Sofia G., Soshnikova, Nataliya V.

“…The PBAF chromatin-remodeling complexes are multi-protein machines, regulating expression of genes involved in proliferation and differentiation. PHF10 is a…”
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SARS-CoV-2 Epitopes Are Recognized by a Public and Diverse Repertoire of Human T Cell Receptors by Shomuradova, Alina S., Vagida, Murad S., Sheetikov, Savely A., Zornikova, Ksenia V., Kiryukhin, Dmitry, Titov, Aleksei, Peshkova, Iuliia O., Khmelevskaya, Alexandra, Dianov, Dmitry V., Malasheva, Maria, Shmelev, Anton, Serdyuk, Yana, Bagaev, Dmitry V., Pivnyuk, Anastasia, Shcherbinin, Dmitrii S., Maleeva, Alexandra V., Shakirova, Naina T., Pilunov, Artem, Malko, Dmitry B., Khamaganova, Ekaterina G., Biderman, Bella, Ivanov, Alexander, Shugay, Mikhail, Efimov, Grigory A.

“…Understanding the hallmarks of the immune response to SARS-CoV-2 is critical for fighting the COVID-19 pandemic. We assessed antibody and T cell reactivity in…”
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MHC-II alleles shape the CDR3 repertoires of conventional and regulatory naïve CD4⁺ T cells by Logunova, Nadezhda N., Kriukova, Valeriia V., Shelyakin, Pavel V., Egorov, Evgeny S., Pereverzeva, Alina, Bozhanova, Nina G., Shugay, Mikhail, Shcherbinin, Dmitrii S., Pogorelyy, Mikhail V., Merzlyak, Ekaterina M., Zubov, Vasiliy N., Meiler, Jens, Chudakov, Dmitriy M., Apt, Alexander S., Britanova, Olga V.

“…T cell maturation and activation depend upon T cell receptor (TCR) interactions with a wide variety of antigenic peptides displayed in a given major…”
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Evaluating performance of existing computational models in predicting CD8+ T cell pathogenic epitopes and cancer neoantigens by Buckley, Paul R, Lee, Chloe H, Ma, Ruichong, Woodhouse, Isaac, Woo, Jeongmin, Tsvetkov, Vasily O, Shcherbinin, Dmitrii S, Antanaviciute, Agne, Shughay, Mikhail, Rei, Margarida, Simmons, Alison, Koohy, Hashem

“…Abstract T cell recognition of a cognate peptide–major histocompatibility complex (pMHC) presented on the surface of infected or malignant cells is of the…”
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Structure-based prediction of T cell receptor recognition of unseen epitopes using TCRen by Karnaukhov, Vadim K, Shcherbinin, Dmitrii S, Chugunov, Anton O, Chudakov, Dmitriy M, Efremov, Roman G, Zvyagin, Ivan V, Shugay, Mikhail

“…T cell receptor (TCR) recognition of foreign peptides presented by major histocompatibility complex protein is a major event in triggering the adaptive immune…”
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Computer-aided design of aptamers for cytochrome p450 by Shcherbinin, Dmitrii S., Gnedenko, Oksana V., Khmeleva, Svetlana A., Usanov, Sergey A., Gilep, Andrei A., Yantsevich, Aliaksei V., Shkel, Tatsiana V., Yushkevich, Ivan V., Radko, Sergey P., Ivanov, Alexis S., Veselovsky, Alexander V., Archakov, Alexander I.

“…Aptamers are short single-stranded DNA or RNA oligonucleotides that can bind to their targets with high affinity and specificity. Usually, they are…”
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Biological Evaluation of a New Brassinosteroid: Antiproliferative Effects and Targeting Estrogen Receptor α Pathways by Scherbakov, Alexander M., Zhabinskii, Vladimir N., Khripach, Vladimir A., Shcherbinin, Dmitrii S., Mekhtiev, Arif R., Shchegolev, Yuri Yu, Savochka, Aleh P., Andreeva, Olga E.

“…Brassinosteroids (BS), a class of plant‐specific steroid hormones, are considered as new potential anticancer agents for the treatment of tumors of different…”
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Comprehensive analysis of structural and sequencing data reveals almost unconstrained chain pairing in TCR[alpha][beta] complex by Shcherbinin, Dmitrii S, Belousov, Vlad A, Shugay, Mikhail

“…Antigen recognition by T-cells is guided by the T-cell receptor (TCR) heterodimer formed by [alpha] and [beta] chains. A huge diversity of TCR sequences should…”
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