Search Results - "Shchedrina, Valentina A"

Structure-function relations, physiological roles, and evolution of mammalian ER-resident selenoproteins by Shchedrina, Valentina A, Zhang, Yan, Labunskyy, Vyacheslav M, Hatfield, Dolph L, Gladyshev, Vadim N

“…Selenium is an essential trace element in mammals. The major biological form of this micronutrient is the amino acid selenocysteine, which is present in the…”
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Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models by Schiffer, Mario, Teng, Beina, Gu, Changkyu, Shchedrina, Valentina A, Kasaikina, Marina, Pham, Vincent A, Hanke, Nils, Rong, Song, Gueler, Faikah, Schroder, Patricia, Tossidou, Irini, Park, Joon-Keun, Staggs, Lynne, Haller, Hermann, Erschow, Sergej, Hilfiker-Kleiner, Denise, Wei, Changli, Chen, Chuang, Tardi, Nicholas, Hakroush, Samy, Selig, Martin K, Vasilyev, Aleksandr, Merscher, Sandra, Reiser, Jochen, Sever, Sanja

“…The small molecule Bis-T-23 targets actin polymerization to improve renal morphology and function in several mouse models of kidney injury and disease…”
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Selenoprotein K Binds Multiprotein Complexes and Is Involved in the Regulation of Endoplasmic Reticulum Homeostasis by Shchedrina, Valentina A., Everley, Robert A., Zhang, Yan, Gygi, Steven P., Hatfield, Dolph L., Gladyshev, Vadim N.

“…Selenoprotein K (SelK) is an 11-kDa endoplasmic reticulum (ER) protein of unknown function. Herein, we defined a new eukaryotic protein family that includes…”
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Selenoprotein S is involved in maintenance and transport of multiprotein complexes by Turanov, Anton A, Shchedrina, Valentina A, Everley, Robert A, Lobanov, Alexei V, Yim, Sun Hee, Marino, Stefano M, Gygi, Steven P, Hatfield, Dolph L, Gladyshev, Vadim N

“…SelS (Selenoprotein S) is a selenocysteine-containing protein with roles in ER (endoplasmic reticulum) function and inflammation. It has been implicated in…”
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Regulation of Dynamin Oligomerization in Cells: The Role of Dynamin–Actin Interactions and Its GTPase Activity by Gu, Changkyu, Chang, Joann, Shchedrina, Valentina A., Pham, Vincent A., Hartwig, John H., Suphamungmee, Worawit, Lehman, William, Hyman, Bradley T., Bacskai, Brian J., Sever, Sanja

“…Dynamin is a 96‐kDa protein that has multiple oligomerization states that influence its GTPase activity. A number of different dynamin effectors, including…”
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Identification and Characterization of a Selenoprotein Family Containing a Diselenide Bond in a Redox Motif by Shchedrina, Valentina A., Novoselov, Sergey V., Malinouski, Mikalai Yu, Gladyshev, Vadim N.

“…Selenocysteine (Sec, U) insertion into proteins is directed by translational recoding of specific UGA codons located upstream of a stem-loop structure known as…”
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A Role for Talin in Presynaptic Function by Morgan, Jennifer R., Di Paolo, Gilbert, Werner, Hauke, Shchedrina, Valentina A., Pypaert, Marc, Pieribone, Vincent A., De Camilli, Pietro

“…Talin, an adaptor between integrin and the actin cytoskeleton at sites of cell adhesion, was recently found to be present at neuronal synapses, where its…”
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Analyses of Fruit Flies That Do Not Express Selenoproteins or Express the Mouse Selenoprotein, Methionine Sulfoxide Reductase B1, Reveal a Role of Selenoproteins in Stress Resistance by Shchedrina, Valentina A., Kabil, Hadise, Vorbruggen, Gerd, Lee, Byung Cheon, Turanov, Anton A., Hirosawa-Takamori, Mitsuko, Kim, Hwa-Young, Harshman, Lawrence G., Hatfield, Dolph L., Gladyshev, Vadim N.

“…Selenoproteins are essential in vertebrates because of their crucial role in cellular redox homeostasis, but some invertebrates that lack selenoproteins have…”
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Overexpression of methionine- R-sulfoxide reductases has no influence on fruit fly aging by Shchedrina, Valentina A., Vorbrüggen, Gerd, Lee, Byung Cheon, Kim, Hwa-Young, Kabil, Hadise, Harshman, Lawrence G., Gladyshev, Vadim N.

“…Methionine sulfoxide reductases (Msrs) are enzymes that repair oxidized methionine residues in proteins. This function implicated Msrs in antioxidant defense…”
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pH-dependent substrate preference of pig heart lipoamide dehydrogenase varies with oligomeric state: response to mitochondrial matrix acidification by Klyachko, Natalia L, Shchedrina, Valentina A, Efimov, Alexander V, Kazakov, Sergey V, Gazaryan, Irina G, Kristal, Bruce S, Brown, Abraham M

“…Cycling of intracellular pH has recently been shown to play a critical role in ischemia-reperfusion injury. Ischemia-reperfusion also leads to mitochondrial…”
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pH-dependent Substrate Preference of Pig Heart Lipoamide Dehydrogenase Varies with Oligomeric State by Klyachko, Natalia L., Shchedrina, Valentina A., Efimov, Alexander V., Kazakov, Sergey V., Gazaryan, Irina G., Kristal, Bruce S., Brown, Abraham M.

“…Cycling of intracellular pH has recently been shown to play a critical role in ischemia-reperfusion injury. Ischemia-reperfusion also leads to mitochondrial…”
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Influence of selenoprotein methionine‐R‐sulfoxide reductase B1 on the lifespan of fruit flies by Shchedrina, Valentina A, Vorbruggen, Gerd, Lee, Byung Cheon, Gladyshev, Vadim N

“…Abstract only…”
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