Search Results - "Shcharbin, D."

Dendrimers in gene transfection by Shcharbin, D. G, Klajnert, B, Bryszewska, M

“…Dendrimers are a new class of nanocomposite materials. They are branching polymers whose structure is formed by monomeric subunit branches diverging to all…”
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Non-viral engineering of skin precursor-derived Schwann cells for enhanced NT-3 production in adherent and microcarrier culture by Shakhbazau, A, Shcharbin, D, Bryszewska, M, Kumar, R, Wobma, H M, Kallos, M S, Goncharova, N, Seviaryn, I, Kosmacheva, S, Potapnev, M, Midha, R

“…Genetic engineering of stem cells and their derivatives has the potential to enhance their regenerative capabilities. Here, dendrimer- and lipofection-based…”
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The effect of PAMAM dendrimers on human and bovine serum albumin at different pH and NaCl concentrations by Shcharbin, D., Klajnert, B., Bryszewska, M.

“…The effect of PAMAM G3.5, PAMAM G4 and PAMAM-OH G4 dendrimers on human and bovine serum albumins has been studied by fluorescence spectroscopy at different pH…”
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Fourth generation phosphorus-containing dendrimers: prospective drug and gene delivery carrier by Shcharbin, D, Dzmitruk, V, Shakhbazau, A, Goncharova, N, Seviaryn, I, Kosmacheva, S, Potapnev, M, Pedziwiatr-Werbicka, E, Bryszewska, M, Talabaev, M, Chernov, A, Kulchitsky, V, Caminade, A-M, Majoral, J-P

“…Research concerning new targeting delivery systems for pharmacologically active molecules and genetic material is of great importance. The aim of the present…”
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Biological properties of low molecular mass peptide dendrimers by Klajnert, B., Janiszewska, J., Urbanczyk-Lipkowska, Z., Bryszewska, M., Shcharbin, D., Labieniec, M.

“…A series of new, low molecular mass, lysine-based peptide dendrimers with varying distribution of cationic and aromatic groups in the structure were…”
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Binding properties of polyamidoamine dendrimers by Klajnert, B., Pastucha, A., Shcharbin, D., Bryszewska, M.

“…Dendrimers are globular, hyperbranched polymers possessing a high concentration of surface functional groups and internal cavities. These unique features make…”
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Dendrimer interactions with hydrophobic fluorescent probes and human serum albumin by Shcharbin, D, Klajnert, B, Mazhul, V, Bryszewska, M

“…The interactions between three types of polyamidoamine dendrimers (with anionic, cationic, and neutral charge on a surface) and fluorescent dye…”
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Effect of dendrimers on pure acetylcholinesterase activity and structure by Shcharbin, D., Jokiel, M., Klajnert, B., Bryszewska, M.

“…The effect of polyamidoamine (PAMAM) dendrimers on activity and fluorescence of pure acetylcholinesterase (EC 3.1.1.7.) was studied. It has been shown that all…”
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Does fluorescence of ANS reflect its binding to PAMAM dendrimer? by Shcharbin, D., Szwedzka, M., Bryszewska, M.

“…The analysis of binding between dendrimer and ANS has shown that (1) fluorescence reflects binding of probe to dendrimer, (2) parameters of binding are K b ∼…”
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Estimation of PAMAM Dendrimers' Binding Capacity by Fluorescent Probe ANS by Shcharbin, D., Klajnert, B., Mazhul, V., Bryszewska, M.

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Neurons and Stromal Stem Cells as Targets for Polycation-Mediated Transfection by Shakhbazau, A. V., Shcharbin, D. G., Goncharova, N. V., Seviaryn, I. N., Kosmacheva, S. M., Kartel, N. A., Bryszewska, M., Majoral, J. P., Potapnev, M. P.

“…Expression of transgenes in neurons and stromal/mesenchymal stem cells (MSC) can greatly enhance their therapeutic potential. In transfection experiments, we…”
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Can dendrimer based nanoparticles fight neurodegenerative diseases? Current situation versus other established approaches by Mignani, Serge, Bryszewska, Maria, Zablocka, Maria, Klajnert-Maculewicz, Barbara, Cladera, Josep, Shcharbin, Dzmitry, Majoral, Jean-Pierre

“…For several decades, the treatment of central nervous system (CNS) disorders such as, for instance, Alzheimer’s disease (AD), Huntington’s disease (HD), and…”
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Slow internal dynamics of membrane proteins in mechanisms of protease-induced aggregation of platelets by Mazhul, V, Chernovets, T, Zaitseva, E, Shcharbin, D

“…Room temperature tryptophan phosphorescence (RTTP) of suspensions of human platelets was studied. RTTP spectra and decay kinetics of both intact platelets and…”
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Effect of dendrimers on selected enzymes—Evaluation of nano carriers by Ionov, Maksim, Ihnatsyeu-Kachan, Aliaksei, Michlewska, Sylwia, Shcharbina, Natallia, Shcharbin, Dzmitry, Majoral, Jean-Pierre, Bryszewska, Maria

“…[Display omitted] •Aspartate transaminase, alkaline phosphatase and l-lactic dehydrogenase regulatory plasma proteins were interacted with phosphorus contained…”
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Dendrimer-protein interactions versus dendrimer-based nanomedicine by Shcharbin, Dzmitry, Shcharbina, Natallia, Dzmitruk, Volha, Pedziwiatr-Werbicka, Elzbieta, Ionov, Maksim, Mignani, Serge, de la Mata, F. Javier, Gómez, Rafael, Muñoz-Fernández, Maria Angeles, Majoral, Jean-Pierre, Bryszewska, Maria

“…[Display omitted] •Dendritic polymers are new kinds of nanoparticles.•Dendrimers interact directly with proteins, with regards to their conformation and…”
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The effects of magnesium, acetylsalicylic acid, and emoxypine on platelet aggregation by Loznikova, S. G., Sukhodola, A. A., Shcharbina, N. Yu, Shcharbin, D. G.

“…This paper summarizes the results of investigation of thrombin-induced platelet aggregation in the absence and presence of magnesium sulfate, acetylsalicylic…”
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Binding of poly(amidoamine), carbosilane, phosphorus and hybrid dendrimers to thrombin—Constants and mechanisms by Shcharbin, Dzmitry, Pedziwiatr-Werbicka, Elzbieta, Vcherashniaya, Aliaksandra, Janaszewska, Anna, Marcinkowska, Monika, Goska, Piotr, Klajnert-Maculewicz, Barbara, Ionov, Maksim, Abashkin, Viktar, Ihnatsyeu-Kachan, Aliaksei, de la Mata, F. Javier, Ortega, Paula, Gomez-Ramirez, Rafael, Majoral, Jean-Pierre, Bryszewska, Maria

“…[Display omitted] •Dendrimers rearranged thrombin structure.•Flexible dendrimers increased unstructured state of thrombin.•Rigid dendrimers increased a number…”
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Interference of cationic polymeric nanoparticles with clinical chemistry tests—Clinical relevance by Shcharbin, Dzmitry, Shcharbina, Natallia, Milowska, Katarzyna, de la Mata, Francisco Javier, Muñoz-Fernandez, Maria Angeles, Mignani, Serge, Gomez-Ramirez, Rafael, Majoral, Jean-Pierre, Bryszewska, Maria

“…[Display omitted] The development of medical nanosystems requires knowledge of their behavior in vivo. Clinical chemistry tests are widely used to estimate the…”
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Effect of magnesium, acetylsalicilic acid and emoxypine on aggregation of platelets by Loznikova, S Zh, Sukhodola, A A, Shcharbina, N Iu, Shcharbin, D G

“…The thrombin-induced platelet aggregation was studied in the absence and presence of magnesium sulfate, acetylsalicylic acid and emoxypine. It was found that…”
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Mobility of Chromophores Absorbing Light in the 320–420 nm Range in Transparent and Cataract Lens Tissue by Halets-Bui, I. V., Sukhodol, A. A., Shcharbin, D. G.

“…We have analyzed the spectral and kinetic characteristics of phosphorescence at room temperature on a millisecond time scale for transparent and cataract lens…”
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