Search Results - "Shay, Tal"

CaSTLe - Classification of single cells by transfer learning: Harnessing the power of publicly available single cell RNA sequencing experiments to annotate new experiments by Lieberman, Yuval, Rokach, Lior, Shay, Tal

“…Single-cell RNA sequencing (scRNA-seq) is an emerging technology for profiling the gene expression of thousands of cells at the single cell resolution…”
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Characterization of the Environmental Plasmidome of the Red Sea by Androsiuk, Lucy, Shay, Tal, Tal, Shay

“…Plasmids contribute to microbial diversity and adaptation, providing microorganisms with the ability to thrive in a wide range of conditions in extreme…”
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ImmGen report: sexual dimorphism in the immune system transcriptome by Gal-Oz, Shani Talia, Maier, Barbara, Yoshida, Hideyuki, Seddu, Kumba, Elbaz, Nitzan, Czysz, Charles, Zuk, Or, Stranger, Barbara E., Ner-Gaon, Hadas, Shay, Tal

“…Sexual dimorphism in the mammalian immune system is manifested as more frequent and severe infectious diseases in males and, on the other hand, higher rates of…”
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Conservation and divergence in the transcriptional programs of the human and mouse immune systems by Shay, Tal, Jojic, Vladimir, Zuk, Or, Rothamel, Katherine, Puyraimond-Zemmour, David, Feng, Ting, Wakamatsu, Ei, Benoist, Christophe, Koller, Daphne, Regev, Aviv, Consortium, ImmGen

“…Much of the knowledge about cell differentiation and function in the immune system has come from studies in mice, but the relevance to human immunology,…”
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Genomic responses to inflammation in mouse models mimic humans: We concur, apples to oranges comparisons won’t do by Shay, Tal, Lederer, James A., Benoist, Christophe

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Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis by Novershtern, Noa, Subramanian, Aravind, Lawton, Lee N., Mak, Raymond H., Haining, W. Nicholas, McConkey, Marie E., Habib, Naomi, Yosef, Nir, Chang, Cindy Y., Shay, Tal, Frampton, Garrett M., Drake, Adam C.B., Leskov, Ilya, Nilsson, Bjorn, Preffer, Fred, Dombkowski, David, Evans, John W., Liefeld, Ted, Smutko, John S., Chen, Jianzhu, Friedman, Nir, Young, Richard A., Golub, Todd R., Regev, Aviv, Ebert, Benjamin L.

“…Though many individual transcription factors are known to regulate hematopoietic differentiation, major aspects of the global architecture of hematopoiesis…”
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Correction: CaSTLe - Classification of single cells by transfer learning: Harnessing the power of publicly available single cell RNA sequencing experiments to annotate new experiments by Lieberman, Yuval, Rokach, Lior, Shay, Tal

“…[This corrects the article DOI: 10.1371/journal.pone.0205499.]…”
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Mapping the splicing landscape of the human immune system by Ner-Gaon, Hadas, Peleg, Ronnie, Gazit, Roi, Reiner-Benaim, Anat, Shay, Tal

“…Most human genes code for more than one transcript. Different ratios of transcripts of the same gene can be found in different cell types or states, indicating…”
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Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses by Amit, Ido, Garber, Manuel, Chevrier, Nicolas, Leite, Ana Paula, Donner, Yoni, Eisenhaure, Thomas, Guttman, Mitchell, Grenier, Jennifer K, Li, Weibo, Zuk, Or, Schubert, Lisa A, Birditt, Brian, Shay, Tal, Goren, Alon, Zhang, Xiaolan, Smith, Zachary, Deering, Raquel, McDonald, Rebecca C, Cabili, Moran, Bernstein, Bradley E, Rinn, John L, Meissner, Alex, Root, David E, Hacohen, Nir, Regev, Aviv

“…Models of mammalian regulatory networks controlling gene expression have been inferred from genomic data but have largely not been validated. We present an…”
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JingleBells: A Repository of Immune-Related Single-Cell RNA-Sequencing Datasets by Ner-Gaon, Hadas, Melchior, Ariel, Golan, Nili, Ben-Haim, Yael, Shay, Tal

“…Recent advances in single-cell RNA-sequencing (scRNA-seq) technology increase the understanding of immune differentiation and activation processes, as well as…”
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Transcriptional Regulatory Circuits: Predicting Numbers from Alphabets by Kim, Harold D., Shay, Tal, O'Shea, Erin K., Regev, Aviv

“…Transcriptional regulatory circuits govern how cis and trans factors transform signals into messenger RNA (mRNA) expression levels. With advances in…”
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Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma by MURAT, Anastasia, MIGLIAVACCA, Eugenia, HAINFELLNER, Johannes A, HEPPNER, Frank L, DIETRICH, Pierre-Yves, ZIMMER, Yitzhak, CAIRNCROSS, J. Gregory, JANZER, Robert-Charles, DOMANY, Eytan, DELORENZI, Mauro, STUPP, Roger, HEGI, Monika E, GORLIA, Thierry, LAMBIV, Wanyu L, SHAY, Tal, HAMOU, Marie-France, DE TRIBOLET, Nicolas, REGLI, Luca, WICK, Wolfgang, KOUWENHOVEN, Mathilde C. M

“…Glioblastomas are notorious for resistance to therapy, which has been attributed to DNA-repair proficiency, a multitude of deregulated molecular pathways, and,…”
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Kc and LAI Estimations Using Optical and SAR Remote Sensing Imagery for Vineyards Plots by Beeri, Ofer, Netzer, Yishai, Munitz, Sarel, Mintz, Danielle Ferman, Pelta, Ran, Shilo, Tal, Horesh, Alon, Mey-tal, Shay

“…Daily or weekly irrigation monitoring conducted per sub-field or management zone is an important factor in vine irrigation decision-making. The objective is to…”
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The transcriptional landscape of the giant freshwater prawn: Embryonic development and early sexual differentiation mechanisms by Grinshpan, Nufar, Abayed, Faiza A A, Wahl, Melody, Ner-Gaon, Hadas, Manor, Rivka, Sagi, Amir, Shay, Tal

“…The giant freshwater prawn pj is one of the best studied species in aquaculture. However, the transcriptional changes associated with embryonic development and…”
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Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells by Cohen, Nadia R, Brennan, Patrick J, Shay, Tal, Watts, Gerald F, Brigl, Manfred, Kang, Joonsoo, Brenner, Michael B

“…Using the Immunological Genome compendium, Brenner and colleagues shed light on the transcriptional programs that operate during the course of i NKT cell…”
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EGR1 and the ERK‐ERF axis drive mammary cell migration in response to EGF by Tarcic, Gabi, Avraham, Roi, Pines, Gur, Amit, Ido, Shay, Tal, Lu, Yiling, Zwang, Yaara, Katz, Menachem, Ben‐Chetrit, Nir, Jacob‐Hirsch, Jasmine, Virgilio, Laura, Rechavi, Gideon, Mavrothalassitis, George, Mills, Gordon B., Domany, Eytan, Yarden, Yosef

“…The signaling pathways that commit cells to migration are incompletely understood. We employed human mammary cells and two stimuli: epidermal growth factor…”
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Two Phases of Mitogenic Signaling Unveil Roles for p53 and EGR1 in Elimination of Inconsistent Growth Signals by Zwang, Yaara, Sas-Chen, Aldema, Drier, Yotam, Shay, Tal, Avraham, Roi, Lauriola, Mattia, Shema, Efrat, Lidor-Nili, Efrat, Jacob-Hirsch, Jasmine, Amariglio, Ninette, Lu, Yiling, Mills, Gordon B., Rechavi, Gideon, Oren, Moshe, Domany, Eytan, Yarden, Yosef

“…Normal cells require continuous exposure to growth factors in order to cross a restriction point and commit to cell-cycle progression. This can be replaced by…”
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Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop by Valenti, Fabio, Fausti, Francesca, Biagioni, Francesca, Shay, Tal, Fontemaggi, Giulia, Domany, Eytan, Yaffe, Michael B., Strano, Sabrina, Blandino, Giovanni, Di Agostino, Silvia

“…Aberrant activation of kinases has emerged to be a key event along with tumor progression, maintenance of tumor phenotype and response to anticancer…”
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The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence by Lambiv, Wanyu L., Vassallo, Irene, Delorenzi, Mauro, Shay, Tal, Diserens, Annie-Claire, Misra, Anjan, Feuerstein, Burt, Murat, Anastasia, Migliavacca, Eugenia, Hamou, Marie-France, Sciuscio, Davide, Burger, Raphael, Domany, Eytan, Stupp, Roger, Hegi, Monika E.

“…Gene expression-based prediction of genomic copy number aberrations in the chromosomal region 12q13 to 12q15 that is flanked by MDM2 and CDK4 identified Wnt…”
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Transcriptome analysis identifies regulators of hematopoietic stem and progenitor cells by Gazit, Roi, Garrison, Brian S, Rao, Tata Nageswara, Shay, Tal, Costello, James, Ericson, Jeff, Kim, Francis, Collins, James J, Regev, Aviv, Wagers, Amy J, Rossi, Derrick J

“…Hematopoietic stem cells (HSCs) maintain blood homeostasis and are the functional units of bone marrow transplantation. To improve the molecular understanding…”
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