Search Results - "Shaw, Walter N"

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    Effect of streptozocin-induced diabetes on insulin-receptor tyrosine kinase activity in obese Zucker rats by SLIEKER, L. J, ROBERTS, E. F, SHAW, W. N, JOHNSON, W. T

    Published in Diabetes (New York, N.Y.) (01-05-1990)
    “…We examined insulin binding, insulin-stimulated autophosphorylation, and phosphorylation of poly(Glu.Na,Tyr)4:1 by liver and skeletal muscle insulin receptor…”
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    Insulin-treated Zucker diabetic fatty rats retain the hypertriglyceridemia associated with obesity by Sparks, Janet D., Shaw, Walter N., Corsetti, James P., Bolognino, Mary, Pesek, Joseph F., Sparks, Charles E.

    Published in Metabolism, clinical and experimental (01-11-2000)
    “…Lipoprotein and apolipoprotein changes were evaluated in 10-week-old Zucker diabetic fatty (ZDF) male rats following 12 weeks of insulin treatment, which…”
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    3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines: opioid antagonists with potent anorectant activity by Mitch, Charles H, Leander, J. David, Mendelsohn, Laurane G, Shaw, Walter N, Wong, David T, Cantrell, Buddy E, Johnson, Bryan G, Reel, John K, Snoddy, John D

    Published in Journal of medicinal chemistry (01-10-1993)
    “…A series of (3R*,4R*)-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine opioid antagonists with varying substituents on the nitrogen were evaluated for their effect…”
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    Genetics of obesity in zucker rats and koletsky rats by Yen, T T, Shaw, W N, Yu, P L

    Published in Heredity (01-06-1977)
    “…The breeding data on Zucker rats and on Koletsky rats confirm that the obesity in these two strains of rats is inherited recessively and results from single…”
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    Glucuronic acid pathway activity in adipose tissue by Winegrad, Albert I, Shaw, Walter N

    Published in The American journal of physiology (01-01-1964)
    “…1 The George S. Cox Medical Institute, University of Pennsylvania, Philadelphia, Pennsylvania 2 The George S. Cox Medical Research Institute, University of…”
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    Long-term treatment of obese Zucker rats with LY255582 and other appetite suppressants by Shaw, W N

    Published in Pharmacology, biochemistry and behavior (01-11-1993)
    “…LY255582, administered subcutaneously, decreased food intake and body weight gain of fed obese Zucker rats during the entire 30-day period of treatment. No…”
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    Novel agents effective against solid tumors: the diarylsulfonylureas. Synthesis, activities, and analysis of quantitative structure-activity relationships by Howbert, J. Jeffry, Grossman, C. Sue, Crowell, Thomas A, Rieder, Brent J, Harper, Richard W, Kramer, Kenneth E, Tao, Eddie V, Aikins, James, Poore, Gerald A

    Published in Journal of medicinal chemistry (01-09-1990)
    “…A series of diarylsulfonylureas with exceptionally broad-spectrum activity against syngeneic rodent solid tumors in vivo is described. Their discovery resulted…”
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    The diabetic Zucker fatty rat by Clark, J B, Palmer, C J, Shaw, W N

    “…A noninsulin-dependent diabetes appeared in fatty rats in our Zucker rat colony. A breeding program yielded a genetic pattern of diabetes consistent with a…”
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    (A-C-B) human proinsulin, a novel insulin agonist and intermediate in the synthesis of biosynthetic human insulin by Heath, W F, Belagaje, R M, Brooke, G S, Chance, R E, Hoffmann, J A, Long, H B, Reams, S G, Roundtree, C, Shaw, W N, Slieker, L J

    Published in The Journal of biological chemistry (05-01-1992)
    “…The hormone insulin is synthesized in the beta cell of the pancreas as the precursor, proinsulin, where the carboxyl terminus of the B-chain is connected to…”
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    Effect of porcine proinsulin in vitro on adipose tissue and diaphragm of the normal rat by Shaw, W N, Chance, R E

    Published in Diabetes (New York, N.Y.) (01-12-1968)
    “…The effect in vitro of porcine proinsulin and single component porcine insulin on the epididymal adipose tissue and the isolated diaphragm of the normal rat…”
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    LY226936 administered orally and centrally to obese Zucker rats suppresses food intake and body weight gain by Shaw, W.N, Clemens, J.A, Panetta, J.A

    Published in Obesity research (01-09-1994)
    “…LY226936, methylcarbamothoic acid‐S‐(4,5‐dihydro‐2‐thiazolyl) ester, is a new compound that, when administered to obese Zucker rats, caused reduced food…”
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