Search Results - "Shaw, Sophie"

Candida auris undergoes adhesin-dependent and -independent cellular aggregation by Pelletier, Chloe, Shaw, Sophie, Alsayegh, Sakinah, Brown, Alistair J P, Lorenz, Alexander

“…Candida auris is a fungal pathogen of humans responsible for nosocomial infections with high mortality rates. High levels of resistance to antifungal drugs and…”
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Formate cross‐feeding and cooperative metabolic interactions revealed by transcriptomics in co‐cultures of acetogenic and amylolytic human colonic bacteria by Laverde Gomez, Jenny A., Mukhopadhya, Indrani, Duncan, Sylvia H., Louis, Petra, Shaw, Sophie, Collie‐Duguid, Elaina, Crost, Emmanuelle, Juge, Nathalie, Flint, Harry J.

“…Summary Interspecies cross‐feeding is a fundamental factor in anaerobic microbial communities. In the human colon, formate is produced by many bacterial…”
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Changes in the gut microbiota of Nigerian infants within the first year of life by Oyedemi, Omolanke T, Shaw, Sophie, Martin, Jennifer C, Ayeni, Funmilola A, Scott, Karen P

“…The composition of the gut microbiota plays an important role in maintaining the balance between health and disease. However, there is considerably less…”
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Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration by Smith, Bryan, Kiessling, Andrea, Lledo-Garcia, Rocio, Dixon, Kate L, Christodoulou, Louis, Catley, Matthew C, Atherfold, Paul, D'Hooghe, Lena E, Finney, Helene, Greenslade, Kevin, Hailu, Hanna, Kevorkian, Lara, Lightwood, Daniel, Meier, Christoph, Munro, Rebecca, Qureshi, Omar, Sarkar, Kaushik, Shaw, Sophie P, Tewari, Roohi, Turner, Alison, Tyson, Kerry, West, Shauna, Shaw, Stevan, Brennan, Frank R

“…Rozanolixizumab (UCB7665), a humanized high-affinity anti-human neonatal Fc receptor (FcRn) monoclonal antibody (IgG4P), has been developed to reduce…”
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Nationwide Stepwise Emergence and Evolution of Multidrug-Resistant Campylobacter jejuni Sequence Type 5136, United Kingdom by Lopes, Bruno S, Strachan, Norval J C, Ramjee, Meenakshi, Thomson, Anne, MacRae, Marion, Shaw, Sophie, Forbes, Ken J

“…We examined whole-genome-sequenced Campylobacter jejuni and C. coli from 2012-2015 isolated from birds and human stool samples in North East Scotland for the…”
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Fetal androgen exposure is a determinant of adult male metabolic health by Siemienowicz, Katarzyna J., Filis, Panagiotis, Shaw, Sophie, Douglas, Alex, Thomas, Jennifer, Mulroy, Sally, Howie, Forbes, Fowler, Paul A., Duncan, W. Colin, Rae, Mick T.

“…Androgen signalling is a critical driver of male development. Fetal steroid signalling can be dysregulated by a range of environmental insults and clinical…”
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Comparative transcriptomics and host-specific parasite gene expression profiles inform on drivers of proliferative kidney disease by Faber, Marc, Shaw, Sophie, Yoon, Sohye, de Paiva Alves, Eduardo, Wang, Bei, Qi, Zhitao, Okamura, Beth, Hartikainen, Hanna, Secombes, Christopher J., Holland, Jason W.

“…The myxozoan parasite, Tetracapsuloides bryosalmonae has a two-host life cycle alternating between freshwater bryozoans and salmonid fish. Infected fish can…”
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Comparison of microbial signatures between paired faecal and rectal biopsy samples from healthy volunteers using next-generation sequencing and culturomics by Mukhopadhya, Indrani, Martin, Jennifer C, Shaw, Sophie, McKinley, Aileen J, Gratz, Silvia W, Scott, Karen P

“…Faecal samples are frequently used to characterise the gut microbiota in health and disease, yet there is considerable debate about how representative faecal…”
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Editorial: Curriculum Applications in Microbiology: Bioinformatics in the Classroom by Melendrez, Melanie Crystal, Shaw, Sophie, Brown, C. Titus, Goodner, Brad W., Kvaal, Christopher

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Integration of Transcriptome, Gross Morphology and Histopathology in the Gill of Sea Farmed Atlantic Salmon ( Salmo salar ): Lessons From Multi-Site Sampling by Król, Elżbieta, Noguera, Patricia, Shaw, Sophie, Costelloe, Eoin, Gajardo, Karina, Valdenegro, Victoria, Bickerdike, Ralph, Douglas, Alex, Martin, Samuel A M

“…The gill of teleost fish is a multifunctional organ involved in many physiological processes such as gas exchange, osmotic and ionic regulation, acid-base…”
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A CO2 sensing module modulates β-1,3-glucan exposure in Candida albicans by Avelar, Gabriela M., Pradhan, Arnab, Ma, Qinxi, Hickey, Emer, Leaves, Ian, Liddle, Corin, Rodriguez Rondon, Alejandra V., Kaune, Ann-Kristin, Shaw, Sophie, Maufrais, Corinne, Sertour, Natacha, Bain, Judith M., Larcombe, Daniel E., de Assis, Leandro J., Netea, Mihai G., Munro, Carol A., Childers, Delma S., Erwig, Lars P., Brown, Gordon D., Gow, Neil A. R., Bougnoux, Marie-Elisabeth, d'Enfert, Christophe, Brown, Alistair J. P.

“…Microbial species capable of co-existing with healthy individuals, such as the commensal fungus Candida albicans, exploit multifarious strategies to evade our…”
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Gut Mucosal Microbiome Signatures of Colorectal Cancer Differ According to BMI Status by Shaw, Sophie, Berry, Susan, Thomson, John, Murray, Graeme I, El-Omar, Emad, Hold, Georgina L

“…Carrying excess body weight is a strong risk factor for colorectal cancer (CRC) development with ~11% of CRC cases in Europe linked to being overweight. The…”
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Pressure and temperature effects on deep‐sea hydrocarbon‐degrading microbial communities in subarctic sediments by Perez Calderon, Luis J., Gontikaki, Evangelia, Potts, Lloyd D., Shaw, Sophie, Gallego, Alejandro, Anderson, James A., Witte, Ursula

“…The Hatton–Rockall Basin (North‐East Atlantic) is an area with potential for deep‐sea (2,900 m) hydrocarbon exploration. Following the Deepwater Horizon oil…”
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The rapid generation of recombinant functional monoclonal antibodies from individual, antigen-specific bone marrow-derived plasma cells isolated using a novel fluorescence-based method by Clargo, Alison M, Hudson, Ashley R, Ndlovu, Welcome, Wootton, Rebecca J, Cremin, Louise A, O'Dowd, Victoria L, Nowosad, Carla R, Starkie, Dale O, Shaw, Sophie P, Compson, Joanne E, White, Dominic P, MacKenzie, Brendon, Snowden, James R, Newnham, Laura E, Wright, Michael, Stephens, Paul E, Griffiths, Meryn R, Lawson, Alastair DG, Lightwood, Daniel J

“…Single B cell technologies, which avoid traditional hybridoma fusion and combinatorial display, provide a means to interrogate the naturally-selected antibody…”
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Foxh1/Nodal Defines Context-Specific Direct Maternal Wnt/β-Catenin Target Gene Regulation in Early Development by Afouda, Boni A., Nakamura, Yukio, Shaw, Sophie, Charney, Rebekah M., Paraiso, Kitt D., Blitz, Ira L., Cho, Ken W.Y., Hoppler, Stefan

“…Although Wnt/β-catenin signaling is generally conserved and well understood, the regulatory mechanisms controlling context-specific direct Wnt target gene…”
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Quantification of ethyl glucuronide, ethyl sulfate, nicotine, and its metabolites in human fetal liver and placenta by Swortwood, Madeleine J., Bartock, Sarah H., Scheidweiler, Karl B., Shaw, Sophie, Filis, Panagiotis, Douglas, Alex, O’Shaughnessy, Peter J., Soffientini, Ugo, Lucendo-Villarin, Baltasar, Iredale, John P., Hay, David C., Fowler, Paul A., Huestis, Marilyn A.

“…Purpose Tobacco and alcohol use during pregnancy is serious public health concerns and result in adverse developmental outcomes. Identifying in utero exposure…”
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Daily Fermented Whey Consumption Alters the Fecal Short-Chain Fatty Acid Profile in Healthy Adults by Smith, Nicola M, Maloney, Niamh G, Shaw, Sophie, Horgan, Graham W, Fyfe, Claire, Martin, Jennifer C, Suter, Andy, Scott, Karen P, Johnstone, Alexandra M

“…Gut microbiota influences many aspects of host health including immune, metabolic, and gut health. We examined the effect of a fermented whey concentrate (FWC)…”
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Role of Candida albicans Tem1 in mitotic exit and cytokinesis by Milne, Stephen W., Cheetham, Jill, Lloyd, Deborah, Shaw, Sophie, Moore, Karen, Paszkiewicz, Konrad H., Aves, Stephen J., Bates, Steven

“…•C. albicans Tem1 is essential for mitotic exit and cytokinesis.•Cells depleted of Tem1 display polarised growth.•Tem1 localises to spindle pole bodies in a…”
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The Effect of Vitamin D on Intestinal Inflammation and Faecal Microbiota in Patients with Ulcerative Colitis by Garg, Mayur, Hendy, Philip, Ding, John Nik, Shaw, Sophie, Hold, Georgina, Hart, Ailsa

“…Vitamin D may be immunomodulatory and alter faecal microbiota, but results from clinical studies in humans to date have been inconclusive. This study aimed to…”
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Rapid genome sequencing for pediatrics by Jezkova, Jana, Shaw, Sophie, Taverner, Nicola V., Williams, Hywel J.

“…The advancements made in next‐generation sequencing (NGS) technology over the past two decades have transformed our understanding of genetic variation in…”
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