Search Results - "Shaw, P.N."

Effects of salinity on antibiotic production in sponge‐derived Salinispora actinobacteria by Ng, Y.K, Hodson, M.P, Hewavitharana, A.K, Bose, U, Shaw, P.N, Fuerst, J.A

“…AIMS: To investigate the effects of growth conditions related to marine habitat on antibiotic production in sponge‐derived Salinispora actinobacteria. METHODS…”
Get full text

Collection and determination of nucleotide metabolites in neonatal and adult saliva by high performance liquid chromatography with tandem mass spectrometry by Al-Shehri, S., Henman, M., Charles, B.G., Cowley, D., Shaw, P.N., Liley, H., Tomarchio, A., Punyadeera, C., Duley, J.A.

“…Saliva contains a number of biochemical components which may be useful for diagnosis/monitoring of metabolic disorders, and as markers of cancer or heart…”
Get full text

Global metabolite analysis of the land snail Theba pisana hemolymph during active and aestivated states by Bose, U., Centurion, E., Hodson, M.P., Shaw, P.N., Storey, K.B., Cummins, S.F.

“…The state of metabolic dormancy has fascinated people for hundreds of years, leading to research exploring the identity of natural molecular components that…”
Get full text

Development of an HPLC–MS/MS method for the selective determination of paracetamol metabolites in mouse urine by Hewavitharana, A.K., Lee, S., Dawson, P.A., Markovich, D., Shaw, P.N.

“…An HPLC–MS/MS method has been developed for the selective quantitative analysis of paracetamol and its two major metabolites. The use of tandem MS enabled the…”
Get full text

A novel, quorum sensor-infused liposomal drug delivery system suppresses Candida albicans biofilms by Bandara, H.M.H.N., Hewavitharana, A.K., Shaw, P.N., Smyth, H.D.C., Samaranayake, L.P.

“…[Display omitted] •Fluconazole and P. aeruginosa QSM, C12AHL loaded liposomes were prepared.•New liposomes significantly reduced viability and biomass of C…”
Get full text

Traditional Aboriginal Preparation Alters the Chemical Profile of Carica papaya Leaves and Impacts on Cytotoxicity towards Human Squamous Cell Carcinoma by Nguyen, Thao T, Parat, Marie-Odile, Shaw, Paul N, Hewavitharana, Amitha K, Hodson, Mark P

“…Carica papaya leaf decoction, an Australian Aboriginal remedy, has been used widely for its healing capabilities against cancer, with numerous anecdotal…”
Get full text

The effect of breastmilk and saliva combinations on the in vitro growth of oral pathogenic and commensal microorganisms by Sweeney, E. L., Al-Shehri, S. S., Cowley, D. M., Liley, H. G., Bansal, N., Charles, B. G., Shaw, P. N., Duley, J. A., Knox, C. L.

“…Neonates are exposed to microbes in utero and at birth, thereby establishing their microbiota (healthy microbial colonisers). Previously, we reported…”
Get full text

Intestinal lymphatic transport of three retinoids in the rat after oral administration: Effect of lipophilicity and lipid vehicle by Nankervis, R., Davis, S.S., Day, N.H., Shaw, P.N.

“…The retinoids are highly lipophilic molecules and are known to be transported in the intestinal lymph after oral administration. Three retinoids, isotretinoin,…”
Get full text

The efficacy of Dynorphin fragments at the κ, μ and δ opioid receptor in transfected HEK cells and in an animal model of unilateral peripheral inflammation by Morgan, M., Heffernan, A., Benhabib, F., Wagner, S., Hewavitharana, A.K., Shaw, P.N., Cabot, P.J.

“…•Inflammatory biotransformation dynorphin 1–17 produces peptide fragments that retain kappa and delta opioid receptor activity.•Dynorphin 1–7 a metabolite of…”
Get full text

Effects of the Mango Components Mangiferin and Quercetin and the Putative Mangiferin Metabolite Norathyriol on the Transactivation of Peroxisome Proliferator-Activated Receptor Isoforms by Wilkinson, Ashley S, Monteith, Gregory R, Shaw, P. Nicholas, Lin, Chun-Nam, Gidley, Michael J, Roberts-Thomson, Sarah J

“…Mangos are a source of bioactive compounds with potential health-promoting activity. This study evaluated the abilities of the mango components quercetin and…”
Get full text

Dynorphin A 1–17 biotransformation in inflamed tissue, serum and trypsin solution analysed by liquid chromatography–tandem mass spectrometry by Morgan, M., Herath, H. M. D. R., Cabot, P. J., Shaw, P. N., Hewavitharana, A. K.

“…Dynorphin A 1–17 (DYN A) is an endogenous neuropeptide that is of interest due to its diverse roles in analgesia, inflammation and addiction. Upon release, DYN…”
Get full text

Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments by Mutalik, S., Hewavitharana, A.K., Shaw, P.N., Anissimov, Y.G., Roberts, M.S., Parekh, H.S.

“…The aim of the present work was to develop and validate a simple RP-HPLC method with UV detection to quantify peptide dendrimers in skin permeation…”
Get full text

A rapid method for the simultaneous determination of the major metabolites of sulphasalazine in plasma by Shaw, P N, Sivner, A L, Aarons, L, Houston, J B

Get more information

Preparation of immuno-stimulating complexes (ISCOMs) by ether injection by Pham, H.L., Shaw, P.N., Davies, N.M.

“…This study investigated the application of the solvent dispersion technique, specifically ether injection, which has been successfully used in the preparation…”
Get full text

Measurement of amoxicillin in plasma and gastric samples using high-performance liquid chromatography with fluorimetric detection by Wibawa, J.I.D, Fowkes, D, Shaw, P.N, Barrett, D.A

“…A rapid, selective and sensitive HPLC assay has been developed for the routine analysis of amoxicillin in rat plasma, gastric juice aspirate and gastric tissue…”
Get full text

Quantification of clarithromycin, its 14-hydroxy and decladinose metabolites in rat plasma, gastric juice and gastric tissue using high-performance liquid chromatography with electrochemical detection by Wibawa, J.I.D, Shaw, P.N, Barrett, D.A

“…A rapid, selective and sensitive HPLC assay has been developed for the simultaneous analysis of clarithromycin, its 14-hydroxy-clarithromycin metabolite, and…”
Get full text

Shortcomings of protein removal prior to high performance liquid chromatographic analysis—A case study using method development for BAY 11-7082 by Hewavitharana, A.K., Hyde, C., Thomas, R., Shaw, P.N.

“…During the analytical method development for BAY 11-7082 ((E)-3-[4-methylphenylsulfonyl]-2-propenenitrile), using HPLC-MS–MS and HPLC-UV, we observed that the…”
Get full text

Rapid and selective high-performance liquid chromatographic method for the determination of metronidazole and its active metabolite in human plasma, saliva and gastric juice by Jessa, M.J., Barrett, D.A., Shaw, P.N., Spiller, R.C.

“…A rapid and selective HPLC method has been developed for the separation and quantitation of metronidazole and its hydroxylated metabolite in human plasma,…”
Get full text

Reversed-phase high-performance liquid chromatographic assay methods for the analysis of a range of penicillins in in vitro permeation studies by Erah, P.O, Barrett, D.A, Shaw, P.N

“…Simple, rapid and selective HPLC methods have been developed for the analysis of amoxycillin, ampicillin, epicillin, mecillinam and propicillin. A Hypersil ODS…”
Get full text

Impact of acid secretion, gastritis, and mucus thickness on gastric transfer of antibiotics in rats by Sherwood, P V, Wibawa, J I D, Atherton, J C, Jordan, N, Jenkins, D, Barrett, D A, Shaw, P N, Spiller, R C

“…Background and aims: The success of Helicobacter pylori eradication regimens depends on gastric pH, inflammation, and mucus thickness. Our aim was to…”
Get full text