Search Results - "Shaw, Lindsey"

Small things considered: the small accessory subunits of RNA polymerase in Gram-positive bacteria by Weiss, Andy, Shaw, Lindsey N.

“…The DNA-dependent RNA polymerase core enzyme in Gram-positive bacteria consists of seven subunits. Whilst four of them (α2ββ′) are essential, three smaller…”
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Epistatic relationships between sarA and agr in Staphylococcus aureus biofilm formation by Beenken, Karen E, Mrak, Lara N, Griffin, Linda M, Zielinska, Agnieszka K, Shaw, Lindsey N, Rice, Kelly C, Horswill, Alexander R, Bayles, Kenneth W, Smeltzer, Mark S

“…The accessory gene regulator (agr) and staphylococcal accessory regulator (sarA) play opposing roles in Staphylococcus aureus biofilm formation. There is…”
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Staphopains Modulate Staphylococcus aureus Biofilm Integrity by Mootz, Joe M, Malone, Cheryl L, Shaw, Lindsey N, Horswill, Alexander R

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Phagocytosis of Staphylococcus aureus by macrophages exerts cytoprotective effects manifested by the upregulation of antiapoptotic factors by Koziel, Joanna, Maciag-Gudowska, Agnieszka, Mikolajczyk, Tomasz, Bzowska, Malgorzata, Sturdevant, Daniel E, Whitney, Adeline R, Shaw, Lindsey N, DeLeo, Frank R, Potempa, Jan

“…It is becoming increasingly apparent that Staphylococcus aureus are able to survive engulfment by macrophages, and that the intracellular environment of these…”
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Screening transcriptional connections in Staphylococcus aureus using high-throughput transduction of bioluminescent reporter plasmids by Weiss, Andy, Jackson, Jessica K, Shaw, Lindsey N, Skaar, Eric P

“…Characterization of transcriptional networks is one of the main strategies used to understand how bacteria interact with their environment. To reveal novel…”
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Galectin-3 Is a Target for Proteases Involved in the Virulence of Staphylococcus aureus by Elmwall, Jonas, Kwiecinski, Jakub, Na, Manli, Ali, Abukar Ahmed, Osla, Veronica, Shaw, Lindsey N, Wang, Wanzhong, Sävman, Karin, Josefsson, Elisabet, Bylund, Johan, Jin, Tao, Welin, Amanda, Karlsson, Anna

“…is a major cause of skin and soft tissue infection. The bacterium expresses four major proteases that are emerging as virulence factors: aureolysin (Aur), V8…”
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Antibacterial Activity of a Series of N 2,N 4‑Disubstituted Quinazoline-2,4-diamines by Van Horn, Kurt S, Burda, Whittney N, Fleeman, Renee, Shaw, Lindsey N, Manetsch, Roman

“…A series of N 2,N 4-disubstituted quinazoline-2,4-diamines has been synthesized and tested against multidrug resistant Staphylococcus aureus. A…”
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Regulatory Requirements for Staphylococcus aureus Nitric Oxide Resistance by Grosser, Melinda R, Weiss, Andy, Shaw, Lindsey N, Richardson, Anthony R

“…The ability of Staphylococcus aureus to resist host innate immunity augments the severity and pervasiveness of its pathogenesis. Nitric oxide (NO˙) is an…”
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Global analysis of transcriptional regulators in Staphylococcus aureus by Ibarra, Jose Antonio, Pérez-Rueda, Ernesto, Carroll, Ronan K, Shaw, Lindsey N

“…Staphylococcus aureus is a widely distributed human pathogen capable of infecting almost every ecological niche of the host. As a result, it is responsible for…”
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Mycobacterium abscessus DosRS two-component system controls a species-specific regulon required for adaptation to hypoxia by Simcox, Breven S, Tomlinson, Brooke R, Shaw, Lindsey N, Rohde, Kyle H

“…( ), an emerging opportunistic pathogen, predominantly infects individuals with underlying pulmonary diseases such as cystic fibrosis (CF). Current treatment…”
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Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases by Pemberton, Orville A, Jaishankar, Priyadarshini, Akhtar, Afroza, Adams, Jessie L, Shaw, Lindsey N, Renslo, Adam R, Chen, Yu

“…Gram-negative pathogens expressing serine β-lactamases (SBLs) and metallo-β-lactamases (MBLs), especially those with carbapenemase activity, threaten the…”
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Identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activities by Bionda, Nina, Fleeman, Renee M., de la Fuente-Núñez, César, Rodriguez, Maria C., Reffuveille, Fany, Shaw, Lindsey N., Pastar, Irena, Davis, Stephen C., Hancock, Robert E.W., Cudic, Predrag

“…Treating bacterial infections can be difficult due to innate or acquired resistance mechanisms, and the formation of biofilms. Cyclic lipopeptides derived from…”
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Multiple Classes of Antimicrobial Peptides in Amaranthus tricolor Revealed by Prediction, Proteomics, and Mass Spectrometric Characterization by Moyer, Tessa B, Allen, Jessie L, Shaw, Lindsey N, Hicks, Leslie M

“…Traditional medicinal plants are rich reservoirs of antimicrobial agents, including antimicrobial peptides (AMPs). Advances in genomic sequencing, in silico…”
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Factors contributing to the biofilm-deficient phenotype of Staphylococcus aureus sarA mutants by Tsang, Laura H, Cassat, James E, Shaw, Lindsey N, Beenken, Karen E, Smeltzer, Mark S

“…Mutation of sarA in Staphylococcus aureus results in a reduced capacity to form a biofilm, but the mechanistic basis for this remains unknown. Previous…”
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The novel two-component system AmsSR governs alternative metabolic pathway usage in Acinetobacter baumannii by Casella, Leila G, Torres, Nathanial J, Tomlinson, Brooke R, Shepherd, Mark, Shaw, Lindsey N

“…In this study, we identify a novel two-component system in (herein named AmsSR for regulator of alternative metabolic systems) only present in select…”
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Regulatory networks important for survival of Acinetobacter baumannii within the host by Allen, Jessie L, Tomlinson, Brooke R, Casella, Leila G, Shaw, Lindsey N

“…•A. baumanniiencodes a variety of transcription factors, two component systems, and small RNAs that influence survival during infection.•ABUW_1645 is a novel…”
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Too Hot to Handle: Antibacterial Peptides Identified in Ghost Pepper by Culver, Kevin D, Allen, Jessie L, Shaw, Lindsey N, Hicks, Leslie M

“…spp. (hot peppers) demonstrate a range of interesting bioactive properties spanning anti-inflammatory, antioxidant, and antimicrobial activities. While several…”
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Steroid Drugs Inhibit Bacterial Respiratory Oxidases and Are Lethal Toward Methicillin-Resistant Staphylococcus aureus by Henry, Samantha A, Webster, Calum M, Shaw, Lindsey N, Torres, Nathanial J, Jobson, Mary-Elizabeth, Totzke, Brendan C, Jackson, Jessica K, McGreig, Jake E, Wass, Mark N, Robinson, Gary K, Shepherd, Mark

“…Cytochrome bd complexes are respiratory oxidases found exclusively in prokaryotes that are important during infection for numerous bacterial pathogens. In…”
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The novel protein ScrA acts through the SaeRS two‐component system to regulate virulence gene expression in Staphylococcus aureus by Wittekind, Marcus A., Frey, Andrew, Bonsall, Abigail E., Briaud, Paul, Keogh, Rebecca A., Wiemels, Richard E., Shaw, Lindsey N., Carroll, Ronan K.

“…Staphylococcus aureus is a Gram‐positive commensal that can also cause a variety of infections in humans. S. aureus virulence factor gene expression is under…”
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Synthesis and biological evaluation of backbone-aminated analogues of gramicidin S by Rathman, Benjamin M., Allen, Jessie L., Shaw, Lindsey N., Del Valle, Juan R.

“…[Display omitted] We report the parallel synthesis of gramicidin S derivatives featuring backbone N-amino substituents. Analogues were prepared by…”
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