Search Results - "Shaw, Janet"

Promoting Meaningful Learning through Incorporation of Creative Exercises in Inorganic Chemistry by Shaw, Janet L.

“…Assessments that are open-ended and student-centered may be used to encourage formation of networks between prerequisite material and new course content…”
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Physical activity and the pelvic floor by Nygaard, Ingrid E., MD, MS, Shaw, Janet M., PhD

“…Pelvic floor disorders are common, with 1 in 4 US women reporting moderate to severe symptoms of urinary incontinence, pelvic organ prolapse, or fecal…”
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Structural basis of mitochondrial receptor binding and constriction by DRP1 by Kalia, Raghav, Wang, Ray Yu-Ruei, Yusuf, Ali, Thomas, Paul V., Agard, David A., Shaw, Janet M., Frost, Adam

“…Mitochondrial inheritance, genome maintenance and metabolic adaptation depend on organelle fission by dynamin-related protein 1 (DRP1) and its mitochondrial…”
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Dynamin Assembly Strategies and Adaptor Proteins in Mitochondrial Fission by Bui, Huyen T., Shaw, Janet M.

“…Mitochondrial fission is mediated by a dynamin-related GTPase that assembles at constricted sites on the organelle. The mechanism of action of this GTPase in…”
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Acute exacerbation of COPD by Ko, Fanny W., Chan, Ka Pang, Hui, David S., Goddard, John R., Shaw, Janet G., Reid, David W., Yang, Ian A.

“…The literature of acute exacerbation of chronic obstructive pulmonary disease (COPD) is fast expanding. This review focuses on several aspects of acute…”
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Miro1-mediated mitochondrial positioning shapes intracellular energy gradients required for cell migration by Schuler, Max-Hinderk, Lewandowska, Agnieszka, Caprio, Giuseppe Di, Skillern, Wesley, Upadhyayula, Srigokul, Kirchhausen, Tom, Shaw, Janet M, Cunniff, Brian

“…It has long been postulated, although never directly demonstrated, that mitochondria are strategically positioned in the cytoplasm to meet local requirements…”
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Moving Mitochondria: Establishing Distribution of an Essential Organelle by Frederick, Rebecca L, Shaw, Janet M

“…Mitochondria form a dynamic network responsible for energy production, calcium homeostasis and cell signaling. Appropriate distribution of the mitochondrial…”
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Prevalence of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among a Largely Middle-Aged Population Utilizing Ultrasound and Liver Biopsy: A Prospective Study by Williams, Christopher D, Stengel, Joel, Asike, Michael I, Torres, Dawn M, Shaw, Janet, Contreras, Maricela, Landt, Cristy L, Harrison, Stephen A

“…Background & Aims Prevalence of nonalcoholic fatty liver disease (NAFLD) has not been well established. The purpose of this study was to prospectively define…”
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Mitochondrial-derived compartments facilitate cellular adaptation to amino acid stress by Schuler, Max-Hinderk, English, Alyssa M., Xiao, Tianyao, Campbell, Thane J., Shaw, Janet M., Hughes, Adam L.

“…Amino acids are essential building blocks of life. However, increasing evidence suggests that elevated amino acids cause cellular toxicity associated with…”
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Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission by Koirala, Sajjan, Guo, Qian, Kalia, Raghav, Bui, Huyen T, Eckert, Debra M, Frost, Adam, Shaw, Janet M

“…Mitochondrial fission is mediated by the dynamin-related GTPases Dnm1/Drp1 (yeast/mammals), which form spirals around constricted sites on mitochondria…”
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Early postpartum physical activity and pelvic floor support and symptoms 1 year postpartum by Nygaard, Ingrid E., Wolpern, Ali, Bardsley, Tyler, Egger, Marlene J., Shaw, Janet M.

“…Risks of pelvic organ prolapse and urinary incontinence increase after the first vaginal delivery. During the early postpartum period, a time of active…”
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Loss of Miro1-directed mitochondrial movement results in a novel murine model for neuron disease by Nguyen, Tammy T, Oh, Sang S, Weaver, David, Lewandowska, Agnieszka, Maxfield, Dane, Schuler, Max-Hinderk, Smith, Nathan K, Macfarlane, Jane, Saunders, Gerald, Palmer, Cheryl A, Debattisti, Valentina, Koshiba, Takumi, Pulst, Stefan, Feldman, Eva L, Hajnóczky, György, Shaw, Janet M

“…Defective mitochondrial distribution in neurons is proposed to cause ATP depletion and calcium-buffering deficiencies that compromise cell function. However,…”
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Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes by Okamoto, Koji, Shaw, Janet M

“…Mitochondria form dynamic tubular networks that continually change their shape and move throughout the cell. In eukaryotes, these organellar gymnastics are…”
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ER-mitochondria contacts promote mitochondrial-derived compartment biogenesis by English, Alyssa M, Schuler, Max-Hinderk, Xiao, Tianyao, Kornmann, Benoît, Shaw, Janet M, Hughes, Adam L

“…Mitochondria are dynamic organelles with essential roles in signaling and metabolism. We recently identified a cellular structure called the…”
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Lifetime physical activity and female stress urinary incontinence by Nygaard, Ingrid E., MD, MS, Shaw, Janet M., PhD, Bardsley, Tyler, MS, Egger, Marlene J., PhD

“…Objective We sought to estimate whether moderate/severe stress urinary incontinence (SUI) in middle-aged women is associated with overall lifetime physical…”
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The impact of acute and chronic strenuous exercise on pelvic floor muscle strength and support in nulliparous healthy women by Middlekauff, Monique L., MS, Egger, Marlene J., PhD, Nygaard, Ingrid E., MD, Shaw, Janet M., PhD

“…Background Strenuous physical activity, which is known to increase intraabdominal pressure and theoretically places stress on the pelvic floor, may affect…”
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Hepatocyte Hypoxia Inducible Factor-1 Mediates the Development of Liver Fibrosis in a Mouse Model of Nonalcoholic Fatty Liver Disease by Mesarwi, Omar A, Shin, Mi-Kyung, Bevans-Fonti, Shannon, Schlesinger, Christina, Shaw, Janet, Polotsky, Vsevolod Y

“…Obstructive sleep apnea (OSA) is associated with the progression of non-alcoholic fatty liver disease (NAFLD) to steatohepatitis and fibrosis. This progression…”
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Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA by MacLachlan, Ian, Judge, Adam D, Sood, Vandana, Shaw, Janet R, Fang, Dianne, McClintock, Kevin

“…Short interfering RNAs (siRNAs) that mediate specific gene silencing through RNA interference (RNAi) are widely used to study gene function and are also being…”
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Rosiglitazone versus rosiglitazone and metformin versus rosiglitazone and losartan in the treatment of nonalcoholic steatohepatitis in humans: A 12‐month randomized, prospective, open‐ label trial by Torres, Dawn M., Jones, Frances J., Shaw, Janet C., Williams, Christopher D., Ward, John A., Harrison, Stephen A.

“…Medication combinations that improve the efficacy of thiazolidinediones or ameliorate weight‐gain side effects of therapy represent an attractive potential…”
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Postpartum sedentary behaviour and pelvic floor support: A prospective cohort study by Shaw, Janet M., Wolpern, Ali, Wu, Jiqiang, Nygaard, Ingrid E., Egger, Marlene J.

“…We evaluated the association between sedentary time and pelvic floor support in primiparas delivered vaginally. The 532 participants (29.2 ± 4.9 years) wore…”
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