Search Results - "Shaw, Helen"

Review of Antimicrobial Resistance in the Environment and Its Relevance to Environmental Regulators by Singer, Andrew C, Shaw, Helen, Rhodes, Vicki, Hart, Alwyn

“…The environment is increasingly being recognized for the role it might play in the global spread of clinically relevant antibiotic resistance. Environmental…”
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Extracellular DNA, cell surface proteins and c-di-GMP promote biofilm formation in Clostridioides difficile by Dawson, Lisa F., Peltier, Johann, Hall, Catherine L., Harrison, Mark A., Derakhshan, Maria, Shaw, Helen A., Fairweather, Neil F., Wren, Brendan W.

“…Clostridioides difficile is the leading cause of nosocomial antibiotic-associated diarrhoea worldwide, yet there is little insight into intestinal tract…”
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Multi-proxy evidence for woodland clearance in northeast Northumberland (England) during the Iron Age by van Asperen, Eline N., Kirby, Jason R., Shaw, Helen E.

“…Pollen diagrams covering the Bronze Age to Roman period from northeast Northumberland are scarce. We present a 14 C-dated pollen record from a peat-filled…”
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Relating dung fungal spore influx rates to animal density in a temperate environment: Implications for palaeoecological studies by van Asperen, Eline N, Kirby, Jason R, Shaw, Helen E

“…The management of the remainder of Europe’s once extensive forests is hampered by a poor understanding of the character of the vegetation and drivers of change…”
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Streptococcus pyogenes Colonization in Children Aged 24–59 Months in the Gambia: Impact of Live Attenuated Influenza Vaccine and Associated Serological Responses by Keeley, Alexander J, Groves, Danielle, Armitage, Edwin P, Senghore, Elina, Jagne, Ya Jankey, Sallah, Hadijatou J, Drammeh, Sainabou, Angyal, Adri, Hornsby, Hailey, de Crombrugghe, Gabrielle, Smeesters, Pierre R, Rossi, Omar, Carducci, Martina, Peno, Chikondi, Bogaert, Debby, Kampmann, Beate, Marks, Michael, Shaw, Helen A, Turner, Claire R, de Silva, Thushan I

“…Abstract Background Immunity to Streptococcus pyogenes in high burden settings is poorly understood. We explored S. pyogenes nasopharyngeal colonization after…”
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Progress towards a glycoconjugate vaccine against Group A Streptococcus by Burns, Keira, Dorfmueller, Helge C., Wren, Brendan W., Mawas, Fatme, Shaw, Helen A.

“…The Group A Carbohydrate (GAC) is a defining feature of Group A Streptococcus (Strep A) or Streptococcus pyogenes . It is a conserved and simple…”
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Cyclic diGMP Regulates Production of Sortase Substrates of Clostridium difficile and Their Surface Exposure through ZmpI Protease-mediated Cleavage by Peltier, Johann, Shaw, Helen A., Couchman, Edward C., Dawson, Lisa F., Yu, Lu, Choudhary, Jyoti S., Kaever, Volkhard, Wren, Brendan W., Fairweather, Neil F.

“…In Gram-positive pathogens, surface proteins may be covalently anchored to the bacterial peptidoglycan by sortase, a cysteine transpeptidase enzyme. In…”
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Prognostic Factors in Cutaneous Desmoplastic Melanoma: A Study of 252 Patients by MURALI, Rajmohan, SHAW, Helen M, LAI, Kenneth, MCCARTHY, Stanley W, QUINN, Michael J, STRETCH, Jonathan R, THOMPSON, John F, SCOLYER, Richard A

“…Desmoplastic melanoma (DM) is a rare subtype of melanoma that is characterized by malignant spindle cells separated by prominent, fibrocollagenous stroma…”
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Early Diagnosis of Cutaneous Melanoma: Revisiting the ABCD Criteria by Abbasi, Naheed R, Shaw, Helen M, Rigel, Darrell S, Friedman, Robert J, McCarthy, William H, Osman, Iman, Kopf, Alfred W, Polsky, David

“…CONTEXT The incidence of cutaneous melanoma has increased over the past several decades, making its early diagnosis a continuing public health priority. The…”
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Multicomponent Vaccines against Group A Streptococcus Can Effectively Target Broad Disease Presentations by Shaw, Helen A., Ozanne, James, Burns, Keira, Mawas, Fatme

“…Group A Streptococcus (GAS) is an important global human pathogen, with a wide range of disease presentations, from mild mucosal infections like pharyngitis to…”
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Disparate subcellular location of putative sortase substrates in Clostridium difficile by Peltier, Johann, Shaw, Helen A., Wren, Brendan W., Fairweather, Neil F.

“…Clostridium difficile is a gastrointestinal pathogen but how the bacterium colonises this niche is still little understood. Sortase enzymes covalently attach…”
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Subungual Melanoma : A Study of 124 Cases Highlighting Features of Early Lesions, Potential Pitfalls in Diagnosis, and Guidelines for Histologic Reporting by TAN, Kong-Bing, MONCRIEFF, Marc, THOMPSON, John F, MCCARTHY, Stanley W, SHAW, Helen M, QUINN, Michael J, LI, Ling-Xi Lawrence, CROTTY, Kerry A, STRETCH, Jonathan R, SCOLYER, Richard A

“…Subungual melanoma (SUM) is an uncommon variant of melanoma that is often difficult to diagnose, both clinically and pathologically. In an attempt to provide…”
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A novel genetic switch controls phase variable expression of CwpV, a Clostridium difficile cell wall protein by Emerson, Jenny E., Reynolds, Catherine B., Fagan, Robert P., Shaw, Helen A., Goulding, David, Fairweather, Neil F.

“…Summary Clostridium difficile is a nosocomial pathogen that can cause severe gastrointestinal infections. C. difficile encodes a family of cell wall proteins,…”
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Detection of first relapse in cutaneous melanoma patients: implications for the formulation of evidence-based follow-up guidelines by Francken, Anne Brecht, Shaw, Helen M, Accortt, Neil A, Soong, Seng-Jaw, Hoekstra, Harald J, Thompson, John F

“…The value of follow-up surveillance for patients with cutaneous melanoma remains uncertain. In this prospective study the frequency of detection of first…”
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Randomised, double-blind, placebo-controlled trial of glycopyrronium in children and adolescents with severe sialorrhoea and neurodisabilities: protocol of the SALIVA trial by Fayoux, Pierre, Dinomais, Mickael, Shaw, Helen, Probert, Nick, Villain, Frédéric, Pouchain, Denis, Texier, Nathalie, Auvin, Stéphane

“…IntroductionSevere sialorrhoea is a common, distressing problem in children/adolescents with neurodisabilities, which has adverse health and social…”
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Prognosis and Determinants of Outcome Following Locoregional or Distant Recurrence in Patients with Cutaneous Melanoma by Francken, Anne Brecht, Accortt, Neil A., Shaw, Helen M., Wiener, Martin, Soong, Seng-jaw, Hoekstra, Harald J., Thompson, John F.

“…Objective Information on prognosis for patients with cutaneous melanoma after locoregional or distant recurrence is sparse and controversial. The aim of this…”
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Tumor mitotic rate is a more powerful prognostic indicator than ulceration in patients with primary cutaneous melanoma: An analysis of 3661 patients from a single center by AZZOLA, Manuela F, SHAW, Helen M, THOMPSON, John F, SOONG, Seng-Jaw, SCOLYER, Richard A, WATSON, Geoffrey F, COLMAN, Marjorie H, YUTING ZHANG

“…The current study was performed to determine whether tumor mitotic rate (TMR) is a useful, independent prognostic factor in patients with localized cutaneous…”
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Atypical Spitzoid Melanocytic Tumors With Positive Sentinel Lymph Nodes in Children and Teenagers, and Comparison With Histologically Unambiguous and Lethal Melanomas by BUSAM, Klaus J, MURALI, Rajmohan, KAYTON, Marc, LAQUAGLIA, Michael, SCOLYER, Richard A, PULITZER, Melissa, MCCARTHY, Stanley W, THOMPSON, John F, SHAW, Helen M, BRADY, Mary S, COIT, Daniel G, DUSZA, Stephen, WILMOTT, James

“…Children and teenagers with a positive sentinel lymph node (SLN) after a prior diagnosis of an atypical spitzoid melanocytic tumor (ASMT) are usually cared for…”
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Sentinel Lymph Node Biopsy in Pediatric and Adolescent Cutaneous Melanoma Patients by Howman-Giles, Robert, Shaw, Helen M., Scolyer, Richard A., Murali, Rajmohan, Wilmott, James, McCarthy, Stanley W., Uren, Roger F., Thompson, John F.

“…Background The rarity of melanoma in young patients, particularly pediatric ones, has to date precluded any valid comparisons being made between young patients…”
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Mainstreaming LEADER Delivery of the RDR in Cumbria: An Interpretative Phenomenological Analysis by Convery, Ian, Soane, Ian, Dutson, Tom, Shaw, Helen

“…The European Union (EU) Rural Development Regulations (RDR) provide the blueprint for EU rural development policy. A major change with the 2007–2013 funding…”
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