Search Results - "Shaw, D E"

The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: an observational study in adults with asthma by Berry, M. A., Shaw, D. E., Green, R. H., Brightling, C. E., Wardlaw, A. J., Pavord, I. D.

“…Summary Background Assessment of eosinophilic airway inflammation may be helpful in the management of asthma. Nitric oxide (NO) has potential advantages as a…”
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Breathing exercises for asthma: a randomised controlled trial by Thomas, M, McKinley, R K, Mellor, S, Watkin, G, Holloway, E, Scullion, J, Shaw, D E, Wardlaw, A, Price, D, Pavord, I

“…The effect of breathing modification techniques on asthma symptoms and objective disease control is uncertain. A prospective, parallel group, single-blind,…”
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Evaluation of the PPAR-γ Agonist Pioglitazone in Mild Asthma: A Double-Blind Randomized Controlled Trial by Anderson, J R, Mortimer, K, Pang, L, Smith, K M, Bailey, H, Hodgson, D B, Shaw, D E, Knox, A J, Harrison, T W

“…Peroxisome proliferator-activated receptor gamma (PPAR-γ) is a nuclear receptor that modulates inflammation in models of asthma. To determine whether…”
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Defining and managing risk in asthma by Blakey, J. D., Zaidi, S., Shaw, D. E.

“…Summary Asthma attacks are a major global source of morbidity and cost. The incidence and impact of asthma attacks have not improved despite widespread…”
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Sputum proteomic signature of gastro-oesophageal reflux in patients with severe asthma by Tariq, K., Schofield, J.P.R., Nicholas, B.L., Burg, D., Brandsma, J., Bansal, A.T., Wilson, S.J., Lutter, R., Fowler, S.J., Bakke, Caruso, M., Dahlen, B., Horváth, I., Krug, N., Montuschi, P., Sanak, M., Sandström, T., Geiser, T., Pandis, I., Sousa, A.R., Adcock, I.M., Shaw, D.E., Auffray, C., Howarth, P.H., Sterk, P.J., Chung, K.F., Skipp, P.J., Dimitrov, B., Djukanović, R.

“…Gastro-oesophageal reflux disease (GORD) has long been associated with poor asthma control without an established cause-effect relationship. 610 asthmatics…”
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Randomised, Placebo‐Controlled Study of Vigabatrin as First‐Line Treatment of Infantile Spasms by Appleton, R. E., Peters, A. C. B., Mumford, J. P., Shaw, D. E.

“…Purpose: Vigabatrin (VGB) has been shown to be an effective drug in the treatment of infantile spasms (West syndrome) in predominantly retrospective and open…”
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Identification of biomarkers for the antiangiogenic and antitumour activity of the superoxide dismutase 1 (SOD1) inhibitor tetrathiomolybdate (ATN-224) by Doñate, F, Juarez, J C, Burnett, M E, Manuia, M M, Guan, X, Shaw, D E, Smith, E L P, Timucin, C, Braunstein, M J, Batuman, O A, Mazar, A P

“…Tetrathiomolybdate (choline salt; ATN-224), a specific, high-affinity copper binder, is currently being evaluated in several phase II cancer trials. ATN-224…”
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Risk of subtrochanteric and femoral shaft fractures due to bisphosphonate therapy in asthma: a population-based nested case–control study by Chalitsios, C. V., Shaw, D. E., McKeever, T. M.

“…Summary Concerns have been raised over the association between bisphosphonates and atypical fractures in subtrochanteric and femoral shaft regions, but the…”
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Fissure formation in coke. 3: Coke size distribution and statistical analysis by Jenkins, D.R., Shaw, D.E., Mahoney, M.R.

“…A model of coke stabilization, based on a fundamental model of fissuring during carbonisation is used to demonstrate the applicability of the fissuring model…”
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The challenge of measuring IL-33 in serum using commercial ELISA: lessons from asthma by Ketelaar, M. E., Nawijn, M. C., Shaw, D. E., Koppelman, G. H., Sayers, I.

“…Summary Background Interleukin‐33 (IL‐33) has been subject of extensive study in the context of inflammatory disorders, particularly in asthma. Many human…”
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Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma by Berry, Mike, Morgan, Angela, Shaw, Dominick E, Parker, Deborah, Green, Ruth, Brightling, Christopher, Bradding, Peter, Wardlaw, Andrew J, Pavord, Ian D

“…Background:Non-eosinophilic asthma is a potentially important clinicopathological phenotype since there is evidence that it responds poorly to inhaled…”
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The utility of exhaled nitric oxide in patients with suspected asthma by Martin, M J, Wilson, E, Gerrard-Tarpey, W, Meakin, G, Hearson, G, McKeever, T M, Shaw, D E, Harrison, T W

“…The value of FENO measurements in patients with symptoms suggestive of asthma is unclear. We performed an observational study to assess the ability of FENO to…”
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Two‐chain high molecular weight kininogen induces endothelial cell apoptosis and inhibits angiogenesis: partial activity within domain 5 by Zhang, Jing‐Chuan, Claffey, Kevin, Sakthivel, Ramasamy, Darzynkiewicz, Zbigniev, Shaw, David Elliot, Leal, Juan, Wang, Yi‐chun, Lu, Feng‐min, McCrae, Keith R.

“…ABSTRACT We previously reported that the binding of two‐chain high molecular weight kininogen (HKa) to endothelial cells may occur through interactions with…”
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Phase 1 trial of the antiangiogenic peptide ATN-161 (Ac-PHSCN-NH ), a beta integrin antagonist, in patients with solid tumours by Cianfrocca, M E, Kimmel, K A, Gallo, J, Cardoso, T, Brown, M M, Hudes, G, Lewis, N, Weiner, L, Lam, G N, Brown, S C, Shaw, D E, Mazar, A P, Cohen, R B

“…To evaluate the toxicity, pharmacological and biological properties of ATN-161, a five -amino-acid peptide derived from the synergy region of fibronectin,…”
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Assessment of a rapid liquid-based cytology method for measuring sputum cell counts by Martin, M J, Lee, H, Meakin, G, Green, A, Simms, R L, Reynolds, C, Winters, S, Shaw, D E, Soomro, I, Harrison, T W

“…Differential sputum cell counting is not widely available despite proven clinical utility in the management of asthma. We compared eosinophil counts obtained…”
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Evaluation of the PPAR-[gamma] agonist pioglitazone in mild asthma: A double-blind randomized controlled trial by Anderson, J. R, Mortimer, K, Pang, L, Smith, K. M, Bailey, H, Hodgson, D. B, Shaw, D. E, Knox, A. J, Harrison, T. W

“…Background Peroxisome proliferator-activated receptor gamma (PPAR-[gamma]) is a nuclear receptor that modulates inflammation in models of asthma. To determine…”
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The hip joint in Down's syndrome. A study of its structure and associated disease by Shaw, E D, Beals, R K

“…Clinical and roentgenographic examination of the hip was performed in 114 patients with Down's syndrome to study range of motion, roentgenographic anatomy, and…”
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Off-line breath acetone analysis in critical illness by Sturney, S C, Storer, M K, Shaw, G M, Shaw, D E, Epton, M J

“…Analysis of breath acetone could be useful in the Intensive Care Unit (ICU) setting to monitor evidence of starvation and metabolic stress. The aims of this…”
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A multivariate analysis of preoperative risk factors in patients with common bile duct stones: implications for treatment by NEOPTOLEMOS, J. P, SHAW, D. E, CARR-LOCKE, D. L

“…A multivariate analysis of 30 preoperative risk factors was undertaken in 248 patients who underwent surgery alone for common bile duct (CBD) stones and in 190…”
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Clinical risk factors and periventricular leucomalacia by Trounce, J Q, Shaw, D E, Levene, M I, Rutter, N

“…Two hundred infants of below 1501 g at birth were regularly examined with real time ultrasound using a 7.5 MHz transducer. Abnormalities were categorized as…”
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