Search Results - "Shaver, Patti"

Collagen matricryptin promotes cardiac function by mediating scar formation by Grilo, Gabriel A., Cakir, Sirin N., Shaver, Patti R., Iyer, Rugmani P., Whitehead, Kaitlin, McClung, Joseph M., Vahdati, Ali, de Castro Brás, Lisandra E.

“…A peptide mimetic of a collagen-derived matricryptin (p1159) was shown to reduce left ventricular (LV) dilation and fibrosis after 7 days delivery in a mouse…”
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AMP-activated protein kinase inhibits vascular smooth muscle cell proliferation and migration and vascular remodeling following injury by Stone, Joshua D, Narine, Avinash, Shaver, Patti R, Fox, Jonathan C, Vuncannon, Jackson R, Tulis, David A

“…Vascular smooth muscle cell (VSMC) activation promotes a synthetic phenotype that underlies many vessel growth disorders. In this regard it has been suggested…”
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Age- and sex-dependent differences in extracellular matrix metabolism associate with cardiac functional and structural changes by Grilo, Gabriel A., Shaver, Patti R., Stoffel, Hamilton J., Morrow, Caleb Anthony, Johnson, Octavious T., Iyer, Rugmani P., de Castro Brás, Lisandra E.

“…Age-related remodeling of the heart causes structural and functional changes in the left ventricle (LV) that are associated with a high index of morbidities…”
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High Fat Diet Dysregulates Hypothalamic‐Pituitary Axis Gene Expression Levels which are Differentially Rescued by EPA and DHA Ethyl Esters by Shaikh, Saame Raza, Shaver, Patti R., Shewchuk, Brian M.

“…Scope Dietary fat composition can modulate gene expression in peripheral tissues in obesity. Observations of the dysregulation of growth hormone (GH) in…”
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Dopamine receptor D3 agonist (Pramipexole) reduces morphine-induced cardiac fibrosis by Gaweda, Gabriel, Iyer, Rugmani P., Shaver, Patti R., Grilo, Gabriel A., Dinkins, Mai-Lynne, Stoffel, Hamilton J., Clemens, Stefan, de Castro Brás, Lisandra E.

“…Morphine is routinely used for pain management in heart failure patients. However, extended morphine exposure associates with major adverse cardiovascular…”
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Mechanisms of cardioprotection via modulation of the immune response by Grilo, Gabriel A, Shaver, Patti R, de Castro Brás, Lisandra E

“…Highlights • Current research focus on cardioprotective immune-targeted therapeutic approaches. • Ischemic preconditioning is a powerful cardioprotective…”
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Soluble guanylyl cyclase-activated cyclic GMP-dependent protein kinase inhibits arterial smooth muscle cell migration independent of VASP-serine 239 phosphorylation by Holt, Andrew W., Martin, Danielle N., Shaver, Patti R., Adderley, Shaquria P., Stone, Joshua D., Joshi, Chintamani N., Francisco, Jake T., Lust, Robert M., Weidner, Douglas A., Shewchuk, Brian M., Tulis, David A.

“…Coronary artery disease (CAD) accounts for over half of all cardiovascular disease-related deaths. Uncontrolled arterial smooth muscle (ASM) cell migration is…”
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The Prospective Cardioprotective Effects of DPP-4 inhibition in the ischemic myocardium by Grilo, Gabriel A, Shaver, Patti R, de Castro Brás, Lisandra E

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Abstract 577: Matricryptin p1158/59 Improves Cardiac Function Post-myocardial Infarction by Reducing Adverse Remodeling by Grilo, Gabriel A, Shaver, Patti R, Iyer, Rugmani P, de Castro Brás, Lisandra E

“…Abstract only Matricryptins are biologically active peptides, generated from extracellular matrix proteolysis, able to regulate cell function and survival. We…”
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The Roles of Dopamine Receptor 3 in Age- and Sex-dependent Left Ventricular Remodeling by Grilo, Gabriel, Shaver, Patti, Clemens, Stefan, de Castro Brás, Lisandra

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Collagen‐derived matricryptin reduces cardiac dysfunction post‐MI via integrin alpha 4 by Grilo, Gabriel, Shaver, Patti, Iyer, Rugmani, Castro Brás, Lisandra

“…Adverse cardiac remodeling post myocardial infarction (MI) triggers a compensatory maladaptive cardiac response that contributes to heart failure. The…”
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Extracellular Matrix Remodeling with Ageing Associates with Cardiac Functional and Structural Changes in a Sex‐Specific Manner by de Castro Brás, Lisandra, Grilo, Gabriel A., Shaver, Patti R., Stoffel, Hamilton J., Morrow, Caleb Anthony, Johnson, Octavious T., Iyer, Rugmani Padmanabhan

“…Abstract only Age‐related remodeling of the heart causes structural and functional changes in the left ventricle (LV) that are associated with a high index of…”
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Abstract 12780: Collagen Derived Matricryptin Robustly Promotes Angiogenesis Post-myocardial Infarction Reducing Cardiac Dysfunction by Neuhaus, Madeleine, Shaver, Patti R, Lust, Robert M, de Castro Brás, Lisandra E

“…Proteolytically released extracellular matrix (ECM) fragments - matricryptins - exert biological activities usually different from those of the full-length…”
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Physical and Functional Interactions between the Herpes Simplex Virus UL15 and UL28 DNA Cleavage and Packaging Proteins by Koslowski, K M, Shaver, P R, Casey, 2nd, J T, Wilson, T, Yamanaka, G, Sheaffer, A K, Tenney, D J, Pederson, N E

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Abstract 556: The Soluble Guanylyl Cyclase Activator Bay 60-2770 Inhibits Arterial Smooth Muscle Cell Migration in Protein Kinase G-dependent Manner by Holt, Andrew, Martin, Danielle, Shaver, Patti, Adderley, Shaquria, Stone, Joshua, Joshi, Chintamani, Francisco, Jake, Lust, Bob, Shewchuk, Brian, Tulis, David

“…Abstract only Atherosclerotic lower extremity peripheral artery disease (PAD) is among the most prevalent, morbid and mortal of all cardiovascular disorders…”
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The Effects of Dopamine Receptor D3 Deficiency in Age‐dependent Left Ventricular Remodeling by Grilo, Gabriel Araujo, Shaver, Patti Rebecca, Stoffel, Hamilton Joseph, Kennedy, Kylie Ruthann, Morrow, Caleb Anthony, Iyer, Rugmani Padmanabhan, Clemens, Stefan, Castro Brás, Lisandra Eunice

“…Aging is an independent risk factor for cardiovascular disease. Additionally, normal aging associates with a decrease on the levels of the neuromodulator…”
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Matricryptin p1158/59 Modulates Vascular Remodeling During Carotid Artery Bypass by Shaver, Patti R, Grilo, Gabriel A, Barefoot, Katherine C, Holt, Andrew W, Tulis, David A, Lust, Robert M, de Castro Brás, Lisandra E.

“…Abstract only When atherosclerosis develops in the coronary arteries, blood flow is compromised and disease progression increases the risk of myocardial…”
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Dopamine Receptor D3 Agonist (Pramipexole) Abolishes Morphine‐Induced Cardiac Fibrosis in Mice by Gaweda, Gabriel G., Iyer, Rugmani P., Shaver, Patti R., Grilo, Gabriel A., Dinkins, Mai‐Lynne, Stoffel, Hamilton J., Clemens, Stefan, Castro Brás, Lisandra E.

“…Prolonged morphine exposure leads to desensitization of the G protein‐coupled mu‐opioid receptor (MOR). Additionally, extended morphine exposure has been shown…”
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AMP‐Activated Protein Kinase Reduces Vascular Smooth Muscle Growth by Inhibiting Actin Cytoskeleton Dynamics Necessary for Migration by Stone, Joshua Daniel, Vuncannon, Jackson R, Shaver, Patti, Fox, Jonathan Clay, Tulis, David Anthony

“…Abstract only Abluminal vascular smooth muscle cell (VSMC) migration is a functional underpinning of vasculoproliferative disorders. Upon activation, the…”
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AMP‐Activated Protein Kinase Reduces Vascular Smooth Muscle Growth by Inhibiting TGF‐β/Smad Signaling and MMP Activity by Stone, Joshua Daniel, Vuncannon, Jackson R, Shaver, Patti, Fox, Jonathan Clay, Tulis, David Anthony

“…Abstract only Aberrant vascular smooth muscle cell (VSMC) growth and extracellular matrix synthesis provides mechanistic underpinning for many vascular…”
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