Search Results - "Shau Poh Chong"

Quantitative microvascular hemoglobin mapping using visible light spectroscopic Optical Coherence Tomography by Chong, Shau Poh, Merkle, Conrad W, Leahy, Conor, Radhakrishnan, Harsha, Srinivasan, Vivek J

“…Quantification of chromophore concentrations in reflectance mode remains a major challenge for biomedical optics. Spectroscopic Optical Coherence Tomography…”
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Cerebral metabolic rate of oxygen (CMRO2) assessed by combined Doppler and spectroscopic OCT by Chong, Shau Poh, Merkle, Conrad W, Leahy, Conor, Srinivasan, Vivek J

“…A method of measuring cortical oxygen metabolism in the mouse brain that uses independent quantitative measurements of three key parameters: cerebral blood…”
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Can OCT Angiography Be Made a Quantitative Blood Measurement Tool? by Zhu, Jun, Merkle, Conrad W, Bernucci, Marcel T, Chong, Shau Poh, Srinivasan, Vivek J

“…Optical Coherence Tomography Angiography (OCTA) refers to a powerful class of OCT scanning protocols and algorithms that selectively enhance the imaging of…”
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Line-scan focal modulation microscopy for rapid imaging of thick biological specimens by Shau Poh Chong, Pant, Shilpa, Nanguang Chen

“…In recent development of fluorescence microscopy, the out-of-focus fluorescence background that arises when imaging deep inside biological tissues is critical…”
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Focal modulation microscopy: a theoretical study by Chong, Shau Poh, Wong, Chee Howe, Sheppard, Colin J R, Chen, Nanguang

“…Focal modulation microscopy is an emerging fluorescence microscopy technique for in vivo imaging of thick biological tissues. Here, we present a theoretical…”
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Optical coherence imaging of hemodynamics, metabolism, and cell viability during brain injury by Srinivasan, Vivek, Shau Poh Chong, Merkle, Conrad William, Radhakrishnan, Harsha, Leahy, Conor

“…Pre-clinical quantitative imaging endpoints have been challenging in mouse models of cerebrovascular disease. Here we present optical coherence imaging…”
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Optical coherence imaging of microvascular oxygenation and hemodynamics by Shau Poh Chong, Merkle, Conrad William, Radhakrishnan, Harsha, Leahy, Conor, Dubra, Alfredo, Sulai, Yusufu N., Srinivasan, Vivek J.

“…Here, we present high-speed spectral domain OCT in the visible spectral range using a supercontinuum source that performs angiography, oximetry, and speed…”
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Influence of laser pulse shape and cleanliness on two-photon microscopy by Chong, Shau Poh, Török, Peter

“…Nonlinear microscopy, including two-photon microscopy, requires pulsed lasers as light source. Typically, when choosing the appropriate pulsed laser for…”
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Noninvasive, in vivo imaging of subcortical mouse brain regions with 1.7  μm optical coherence tomography by Chong, Shau Poh, Merkle, Conrad W, Cooke, Dylan F, Zhang, Tingwei, Radhakrishnan, Harsha, Krubitzer, Leah, Srinivasan, Vivek J

“…A spectral/Fourier domain optical coherence tomography (OCT) intravital microscope using a supercontinuum light source at 1.7 μm was developed to study…”
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Highly parallel, interferometric diffusing wave spectroscopy for monitoring cerebral blood flow dynamics by Zhou, Wenjun, Kholiqov, Oybek, Chong, Shau Poh, Srinivasan, Vivek J

“…Light-scattering methods are widely used in soft matter physics and biomedical optics to probe dynamics in turbid media, such as diffusion in colloids or blood…”
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Structural and functional human retinal imaging with a fiber-based visible light OCT ophthalmoscope by Chong, Shau Poh, Bernucci, Marcel, Radhakrishnan, Harsha, Srinivasan, Vivek J

“…The design of a multi-functional fiber-based Optical Coherence Tomography (OCT) system for human retinal imaging with < 2 micron axial resolution in tissue is…”
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Noninvasive, in vivo rodent brain optical coherence tomography at 2.1  microns by Zhu, Jun, Chong, Shau Poh, Zhou, Wenjun, Srinivasan, Vivek J

“…In biological tissue, longer near-infrared wavelengths generally experience less scattering and more water absorption. Here we demonstrate an optical coherence…”
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Interferometric Near-Infrared Spectroscopy (iNIRS) for determination of optical and dynamical properties of turbid media by Borycki, Dawid, Kholiqov, Oybek, Chong, Shau Poh, Srinivasan, Vivek J

“…We introduce and implement interferometric near-infrared spectroscopy (iNIRS), which simultaneously extracts optical and dynamical properties of turbid media…”
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Multifunctional laser speckle imaging by Du, E, Shen, Shuhao, Chong, Shau Poh, Chen, Nanguang

“…We have developed a multi-functional laser speckle imaging system, which can be operated in both the surface illumination laser speckle contrast imaging…”
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Visible light optical coherence microscopy of the brain with isotropic femtoliter resolution in vivo by Merkle, Conrad William, Chong, Shau Poh, Kho, Aaron Michael, Zhu, Jun, Dubra, Alfredo, Srinivasan, Vivek Jay

“…Most flying-spot optical coherence tomography and optical coherence microscopy (OCM) systems use a symmetric confocal geometry, where the detection path…”
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Ultrahigh resolution retinal imaging by visible light OCT with longitudinal achromatization by Chong, Shau Poh, Zhang, Tingwei, Kho, Aaron, Bernucci, Marcel T, Dubra, Alfredo, Srinivasan, Vivek J

“…Chromatic aberrations are an important design consideration in high resolution, high bandwidth, refractive imaging systems that use visible light. Here, we…”
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Tri-modal microscopy with multiphoton and optical coherence microscopy/tomography for multi-scale and multi-contrast imaging by Chong, Shau Poh, Lai, Tom, Zhou, Yifeng, Tang, Shuo

“…Multi-scale multimodal microscopy is a very useful technique by providing multiple imaging contrasts with adjustable field of views and spatial resolutions…”
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Quantifying the backscattering of second harmonic generation in tissues with confocal multiphoton microscopy by Shen, Mengzhe, Tian, Yunxian, Chong, Shau Poh, Zhao, Jianhua, Zeng, Haishan, Tang, Shuo

“…The backward second harmonic generation (SHG) in mouse tissues is studied with a confocal multiphoton microscopy system. The total backward collected SHG…”
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Simple spatial phase modulator for focal modulation microscopy by Wong, Chee Howe, Chong, Shau Poh, Sheppard, Colin J R, Chen, Nanguang

“…Focal modulation microscopy (FMM) is an emerging microscopy technique for fluorescence imaging of thick biological tissue in vivo. A spatial phase modulator is…”
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Considerations of aperture configuration in focal modulation microscopy from the standpoint of modulation depth by Gao, Guangjun, Chong, Shau Poh, Sheppard, Colin J R, Chen, Nanguang

“…Focal modulation microscopy (FMM) is a simple, yet efficient, method to preserve image quality in terms of signal-to-background ratio by selecting ballistic…”
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