Search Results - "Shattuck, Jenifer"

The prion-like protein kinase Sky1 is required for efficient stress granule disassembly by Shattuck, Jenifer E., Paul, Kacy R., Cascarina, Sean M., Ross, Eric D.

“…Stress granules are membraneless protein- and mRNA-rich organelles that form in response to perturbations in environmental conditions. Stress granule formation…”
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Composition-based prediction and rational manipulation of prion-like domain recruitment to stress granules by Boncella, Amy E., Shattuck, Jenifer E., Cascarina, Sean M., Paul, Kacy R., Baer, Matthew H., Fomicheva, Anastasia, Lamb, Andrew K., Ross, Eric D.

“…Mutations in a number of stress granule-associated proteins have been linked to various neurodegenerative diseases. Several of these mutations are found in…”
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Sky1: at the intersection of prion-like proteins and stress granule regulation by Shattuck, Jenifer E., Cascarina, Sean M., Paul, Kacy R., Ross, Eric D.

“…Serine‐arginine (SR) protein kinases regulate diverse cellular activities, including various steps in RNA maturation and transport. The yeast Saccharomyces…”
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Reduction of the RNA Binding Protein TIA1 Exacerbates Neuroinflammation in Tauopathy by LeBlang, Chelsey Jenna, Medalla, Maria, Nicoletti, Nicholas William, Hays, Emma Catherine, Zhao, James, Shattuck, Jenifer, Cruz, Anna Lourdes, Wolozin, Benjamin, Luebke, Jennifer Irene

“…Neuroinflammatory processes play an integral role in the exacerbation and progression of pathology in tauopathies, a class of neurodegenerative disease…”
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Distinct Amino Acid Compositional Requirements for Formation and Maintenance of the [PSI +] Prion in Yeast by MacLea, Kyle S., Paul, Kacy R., Ben-Musa, Zobaida, Waechter, Aubrey, Shattuck, Jenifer E., Gruca, Margaret, Ross, Eric D.

“…Multiple yeast prions have been identified that result from the structural conversion of proteins into a self-propagating amyloid form. Amyloid-based prion…”
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The effects of glutamine/asparagine content on aggregation and heterologous prion induction by yeast prion-like domains by Shattuck, Jenifer E., Waechter, Aubrey C., Ross, Eric D.

“…Prion-like domains are low complexity, intrinsically disordered domains that compositionally resemble yeast prion domains. Many prion-like domains are involved…”
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TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau by Ash, Peter E. A., Lei, Shuwen, Shattuck, Jenifer, Boudeau, Samantha, Carlomagno, Yari, Medalla, Maria, Mashimo, Bryce L., Socorro, Guillermo, Al-Mohanna, Louloua F. A., Jiang, Lulu, Öztürk, Muhammet M., Knobel, Mark, Ivanov, Pavel, Petrucelli, Leonard, Wegmann, Susanne, Kanaan, Nicholas M., Wolozin, Benjamin

“…Tau protein plays an important role in the biology of stress granules and in the stress response of neurons, but the nature of these biochemical interactions…”
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Investigating the Roles Prion-like Domains Play in Cellular Stress Responses by Shattuck, Jenifer Elizabeth

“…Prion-like domains are involved in the formation of either functional or pathogenic protein aggregates. These aggregates play an important role in regulating a…”
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Analysis of Protein–RNA Complexes Involving a RNA Recognition Motif Engineered To Bind Hairpins with Seven- and Eight-Nucleotide Loops by Blakeley, Brett D, Shattuck, Jenifer, Coates, Melissa B, Tran, Evelyn, Laird-Offringa, Ite A, McNaughton, Brian R

“…U1A binds U1hpII, a hairpin RNA with a 10-nucleotide loop. A U1A mutant (ΔK50ΔM51) binds U1hpII-derived hairpins with shorter loops, making it an interesting…”
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