Search Results - "Shattock, R"

Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques by Moog, C, Dereuddre-Bosquet, N, Teillaud, J-L, Biedma, M E, Holl, V, Van Ham, G, Heyndrickx, L, Van Dorsselaer, A, Katinger, D, Vcelar, B, Zolla-Pazner, S, Mangeot, I, Kelly, C, Shattock, R J, Le Grand, R

“…Definition of antibody (Ab) functions capable of preventing mucosal HIV transmission may be critical to both effective vaccine development and the prophylactic…”
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Specific microbicides in the prevention of HIV infection by Kelly, C. G., Shattock, R. J.

“…  Kelly CG, Shattock RJ (Dental Institute, King’s College London, London; and Imperial College, London; UK). Specific microbicides in the prevention of HIV…”
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Inhibition of Human Immunodeficiency Virus Type 1 Infection by the Candidate Microbicide Dapivirine, a Nonnucleoside Reverse Transcriptase Inhibitor by FLETCHER, P, HARMAN, S, AZIJN, H, ARMANASCO, N, MANLOW, P, PERUMAL, D, DE BETHUNE, M.-P, NUTTALL, J, ROMANO, J, SHATTOCK, R

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Optimising the collection of female genital tract fluid for cytokine analysis in pregnant women by Short, C.S., Quinlan, R., Bennett, P., Shattock, R.J., Taylor, G.P.

“…To better understand the immunology of pregnancy, study of female genital tract fluid (FGF) is desirable. However the optimum method of collection of FGF in…”
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Comparative analysis of enzymatically produced novel linear DNA constructs with plasmids for use as DNA vaccines by Walters, A A, Kinnear, E, Shattock, R J, McDonald, J U, Caproni, L J, Porter, N, Tregoning, J S

“…The use of DNA to deliver vaccine antigens offers many advantages, including ease of manufacture and cost. However, most DNA vaccines are plasmids and must be…”
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Combined skin and muscle vaccination differentially impact the quality of effector T cell functions: the CUTHIVAC-001 randomized trial by Haidari, G., Cope, A., Miller, A., Venables, S., Yan, C., Ridgers, H., Reijonen, K., Hannaman, D., Spentzou, A., Hayes, P., Bouliotis, G., Vogt, A., Joseph, S., Combadiere, B., McCormack, S., Shattock, R. J.

“…Targeting of different tissues via transcutaneous (TC), intradermal (ID) and intramuscular (IM) injection has the potential to tailor the immune response to…”
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HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life by Yates, N L, Stacey, A R, Nolen, T L, Vandergrift, N A, Moody, M A, Montefiori, D C, Weinhold, K J, Blattner, W A, Borrow, P, Shattock, R, Cohen, M S, Haynes, B F, Tomaras, G D

“…Prevention of HIV-1 transmission at mucosal surfaces will likely require durable pre-existing mucosal anti-HIV-1 antibodies (Abs). Defining the ontogeny,…”
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Cyanovirin-N produced in rice endosperm offers effective pre-exposure prophylaxis against HIV-1BaL infection in vitro by Vamvaka, E., Evans, A., Ramessar, K., Krumpe, L. R. H., Shattock, R. J., O’Keefe, B. R., Christou, P., Capell, T.

“…Key message Cyanovirin-N produced in rice endosperm provides efficient pre-exposure prophylaxis against HIV-1 BaL infection in vitro . Cyanovirin-N (CV-N) is a…”
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Fine-mapping the immunodominant antibody epitopes on consensus sequence-based HIV-1 envelope trimer vaccine candidates by Reiss, E. I. M. M., van Haaren, M. M., van Schooten, J., Claireaux, M. A. F., Maisonnasse, P., Antanasijevic, A., Allen, J. D., Bontjer, I., Torres, J. L., Lee, W-H, Ozorowski, G., Vázquez Bernat, N., Kaduk, M., Aldon, Y., Burger, J. A., Chawla, H., Aartse, A., Tolazzi, M., Gao, H., Mundsperger, P., Crispin, M., Montefiori, D. C., Karlsson Hedestam, G. B., Scarlatti, G., Ward, A. B., Le Grand, R., Shattock, R., Dereuddre-Bosquet, N., Sanders, R. W., van Gils, M. J.

“…The HIV-1 envelope glycoprotein (Env) trimer is the key target for vaccines aimed at inducing neutralizing antibodies (NAbs) against HIV-1. The clinical…”
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Crystal engineering of pharmaceutical co-crystals from polymorphic active pharmaceutical ingredients by Vishweshwar, Peddy, McMahon, Jennifer A, Peterson, Matthew L, Hickey, Magali B, Shattock, Tanise R, Zaworotko, Michael J

“…The carboxylic acid-primary amide supramolecular heterosynthon is exploited for the generation of pharmaceutical co-crystals that contain two active…”
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Transferrin conjugation confers mucosal molecular targeting to a model HIV-1 trimeric gp140 vaccine antigen by Mann, J.F.S., Stieh, D., Klein, K., de Stegmann, D.S. Miranda, Cranage, M.P., Shattock, R.J., McKay, P.F.

“…The generation of effective immune responses by mucosal vaccination without the use of inflammatory adjuvants, that compromise the epithelial barrier and…”
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18-Fold Interpenetration and Concomitant Polymorphism in the 2:3 Co-Crystal of Trimesic Acid and 1,2-Bis(4-pyridyl)ethane by Shattock, Tanise R, Vishweshwar, Peddy, Wang, Zhenqiang, Zaworotko, Michael J

“…The 2:3 co-crystal of trimesic acid and 1,2-bis(4-pyridyl)ethane (2) exhibits concomitant polymorphism. Form II of 2 is the expected hexagonal (6,3) network,…”
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Hierarchy of Supramolecular Synthons: Persistent Carboxylic Acid···Pyridine Hydrogen Bonds in Cocrystals That also Contain a Hydroxyl Moiety by Shattock, Tanise R, Arora, Kapildev K, Vishweshwar, Peddy, Zaworotko, Michael J

“…A Cambridge Structural Database (CSD) analysis was conducted in order to evaluate the hierarchy of supramolecular heterosynthons that involve two of the most…”
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Repeated vaginal administration of trimeric HIV-1 clade C gp140 induces serum and mucosal antibody responses by Cranage, M P, Fraser, C A, Stevens, Z, Huting, J, Chang, M, Jeffs, S A, Seaman, M S, Cope, A, Cole, T, Shattock, R J

“…Vaccine-mediated prevention of primary infection with human immunodeficiency virus (HIV) may require the sustained production of antibody at mucosal portals of…”
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Phenotypic and genotypic diversity in Phytophthora infestans on potato in Great Britain, 1995-98 by Day, J.P, Wattier, R.A.M, Shaw, D.S, Shattock, R.C

“…A total of 2691 single‐lesion isolates of Phytophthora infestans was established from samples of late‐blight disease from 354 commercial and garden/allotment…”
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DC-SIGN association with the Th2 environment of lepromatous lesions: cause or effect? by Soilleux, EJ, Sarno, EN, Hernandez, MO, Moseley, E, Horsley, J, Lopes, UG, Goddard, MJ, Vowler, SL, Coleman, N, Shattock, RJ, Sampaio, EP

“…The clinical spectrum of leprosy is related to patients' immune responses. Non‐responsiveness towards Mycobacterium leprae (ML) seems to correlate with a Th2…”
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Target cells in vaginal HIV transmission by Miller, Christopher J., Shattock, Robin J.

“…Understanding the mechanisms of HIV transmission to women will be crucial to the development of effective strategies to curb this epidemic. Current data…”
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Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120 by Moore, John P, Veazey, Ronald S, Shattock, Robin J, Pope, Melissa, Kirijan, J. Christian, Jones, Jennifer, Hu, Qinxue, Ketas, Tom, Marx, Preston A, Klasse, Per Johan, Burton, Dennis R

“…A topical microbicide reduces the probability of virus transmission when applied to the vagina or rectum of a person at risk of sexually acquiring HIV-1…”
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A Comparison of Cocrystal Structure Solutions from Powder and Single Crystal Techniques by Lapidus, Saul H, Stephens, Peter W, Arora, Kapildev K, Shattock, Tanise R, Zaworotko, Michael J

“…We demonstrate the effectiveness and accuracy of high resolution powder diffraction for determination of cocrystal structures through a double-blind study…”
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Microbicides for HIV/AIDS. 3. Observation of Apparent Dynamic Protonation and Deprotonization in CD4+ T-Cell Model Systems by Rowell, R. L, Fairhurst, D, Monahan, I. M, Key, S, Morfesis, A, Stieh, D, Mitchnick, M, Loxley, A, Shattock, R. A

“…New measurements of the electrophoretic mobility of T-cell model systems have been carried out and analyzed to obtain the dynamic variation in mobility in…”
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