Search Results - "Shashkova, E V"

INGN 007, an oncolytic adenovirus vector, replicates in Syrian hamsters but not mice: comparison of biodistribution studies by Ying, B, Toth, K, Spencer, J F, Meyer, J, Tollefson, A E, Patra, D, Dhar, D, Shashkova, E V, Kuppuswamy, M, Doronin, K, Thomas, M A, Zumstein, L A, Wold, W S M, Lichtenstein, D L

“…Preclinical biodistribution studies with INGN 007, an oncolytic adenovirus (Ad) vector, supporting an early stage clinical trial were conducted in Syrian…”
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An acute toxicology study with INGN 007, an oncolytic adenovirus vector, in mice and permissive Syrian hamsters; comparisons with wild-type Ad5 and a replication-defective adenovirus vector by Lichtenstein, D L, Spencer, J F, Doronin, K, Patra, D, Meyer, J M, Shashkova, E V, Kuppuswamy, M, Dhar, D, Thomas, M A, Tollefson, A E, Zumstein, L A, Wold, W S M, Toth, K

“…Oncolytic (replication-competent) adenoviruses as anticancer agents provide new, promising tools to fight cancer. In support of a Phase I clinical trial, here…”
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Anticancer activity of oncolytic adenovirus vector armed with IFN-α and ADP is enhanced by pharmacologically controlled expression of TRAIL by Shashkova, E V, Kuppuswamy, M N, Wold, W S M, Doronin, K

“…We have previously described oncolytic adenovirus (Ad) vectors KD3 and KD3–interferon (IFN) that were rendered cancer-specific by mutations in the E1A region…”
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Specific features of cognitive impairments in patients with predialysis chronic kidney disease by Rogova, I V, Fomin, V V, Damulin, I V, Shashkova, E V

“…To study the specific features of cognitive impairments (CI) in patients with predialysis chronic kidney disease (CKD). Examinations were made in 51 patients…”
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A fully replication-competent adenovirus vector with enhanced oncolytic properties by Toth, K, Kuppuswamy, M, Shashkova, E V, Spencer, J F, Wold, W S M

“…We have studied the oncolytic efficacy of two adenovirus vectors named KD3 and INGN 007, which differ from each other only in that whereas KD3 has two small…”
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Neurocutaneous melanosis concurrent with a posterior cranial fossa cyst (Dandy–Walker complex) and an intradural arachnoid cyst of the spinal canal by Evzikov, G. Yu, Bashlachev, M. G., Shashkova, E. V., Belozerskikh, K. A., Grebenev, F. V.

“…The paper describes a female patient with neurocutaneous melanosis (NCM) concurrent with Dandy–Walker malformation and a spinal arachnoid cyst, who has been…”
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Recombinant avian adenovirus CELO expressing the human interleukin-2: characterization in vitro, in ovo and in vivo by Cherenova, L.V., Logunov, D.Y., Shashkova, E.V., Shmarov, M.M., Verkhovskaya, L.V., Neugodova, G.L., Kazansky, D.B., Doronin, K.K., Naroditsky, B.S.

“…In our study, a recombinant adenovirus based on the avian adenovirus CELO genome, has been constructed that contains the human interleukin-2 gene. We have…”
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The acute tetraparesis as a rare presentation of Chiari malformation by Evzikov, G Yu, Ivanova, M A, Parfenov, V A, Solokha, O A, Shashkova, E V

“…The authors present a case-report of a 25-year-old patient who developed symptoms of transversal injury of the spine. The patient was followed-up for 2 years…”
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Spinal dural arteriovenous fistulas: Pathogenesis, clinical manifestations, diagnosis, treatment by Evzikov, G. Yu, Bublievsky, D. V., Kondrashin, S. A., Sinitsyn, V. E., Shashkova, E. V.

“…The paper describes spinal dural arteriovenous fistulas (SDAVF), the most common type of spinal cord vascular anomalies. SDAVFs account for 60–80% of the…”
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Regression of lumbar disk herniation by Evzikov, G. Yu, Isaikin, A. I., Kavelina, A. V., Shashkova, E. V., Alipbekov, N. N.

“…Compression of the spinal nerve root, giving rise to pain and sensory and motor disorders in the area of its innervation is the most vivid manifestation of…”
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Use of Computer Test Systems for Studying Specific Age-Related Disorders of Higher Brain Function by Damulin, I V, Oryshich, N A, Nadezhdin, D S, Matveev, E V, Shashkova, E V

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Avian adenovirus vector CELO-TK displays anticancer activity in human cancer cells and suppresses established murine melanoma tumors by Shashkova, Elena V, Cherenova, Lubov V, Kazansky, Dmitry B, Doronin, Konstantin

“…Avian adenovirus CELO is a novel adenovirus vector system with the advantages of efficient production, high virion stability, and the absence of…”
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Periodic limb movements in sleep and cerebral small vessel disease progression: a prospective cohort study by Spektor, E D, Koberskaya, N N, Shashkova, E V, Poluektov, M G

“…To determine the predictive role of periodic limb movements in sleep (PLMS) in cerebral small vessel disease (cSVD) progression rate. Fifty patients with cSVD,…”
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Chemical modification with high molecular weight polyethylene glycol reduces transduction of hepatocytes and increases efficacy of intravenously delivered oncolytic adenovirus by Doronin, Konstantin, Shashkova, Elena V, May, Shannon M, Hofherr, Sean E, Barry, Michael A

“…Oncolytic adenoviruses are anticancer agents that replicate within tumors and spread to uninfected tumor cells, amplifying the anticancer effect of initial…”
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Characterization of human adenovirus serotypes 5, 6, 11, and 35 as anticancer agents by Shashkova, Elena V, May, Shannon M, Barry, Michael A

“…Abstract Human adenovirus type 5 (Ad5) has been the most popular platform for the development of oncolytic Ads. Alternative Ad serotypes with low…”
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Anticancer activity of oncolytic adenovirus vector armed with IFN-[alpha] and ADP is enhanced by pharmacologically controlled expression of TRAIL by Shashkova, E V, Kuppuswamy, M N, Wold, W S M, Doronin, K

“…We have previously described oncolytic adenovirus (Ad) vectors KD3 and KD3-interferon (IFN) that were rendered cancer-specific by mutations in the E1A region…”
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Use of computer test systems in the study of age-specific features of higher brain dysfunctions by Damulin, I V, Oryshich, N A, Nadezhdin, D S, Matveev, E V, Shashkova, E V

“…The paper covers the results of the study whose aim was to determine the quantitative and structural features of neurological and neuropsychological disorders…”
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Delivery of secreted placental alkaline phosphatase (SEAP) gene in vitro and in vivo as a component of recombinant avian adenovirus (CELO) by Logunov, D Iu, Cherenova, L V, Shmarov, M M, Shashkova, E V, Verkhovskaia, L V, Doronin, K K, Naroditskiĭ, B S

“…Recombinant adenoviruses capable of expressing the gene of secreted placentary alkaline phosphatase (SEAP) under control of CMV-promoter was obtained on the…”
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Eukaryotic vectors of Celo avian adenovirus genome, carrying GFP and human IL-2 genes by Shmarov, M M, Cherenova, L V, Shashkova, E V, Logunov, D Iu, Verkhovskaia, L V, Kapitonov, A V, Neugodova, G L, Doronin, K K, Naroditskiĭ, B S

“…Recombinant CELO avian adenoviruses carrying green fluorescent protein (GFP) and and human interleukin-2 (IL-2) genes were obtained by homologous recombination…”
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