Search Results - "Shashikumar, Soumya"

Humanized DRAGA mice immunized with Plasmodium falciparum sporozoites and chloroquine elicit protective pre-erythrocytic immunity by Majji, Sai, Wijayalath, Wathsala, Shashikumar, Soumya, Brumeanu, Teodor D, Casares, Sofia

“…Human-immune-system humanized mouse models can bridge the gap between humans and conventional mice for testing human vaccines. The HLA-expressing humanized…”
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HIV-1 infected humanized DRAGA mice develop HIV-specific antibodies despite lack of canonical germinal centers in secondary lymphoid tissues by Ollerton, Matthew T, Folkvord, Joy M, Peachman, Kristina K, Shashikumar, Soumya, Morrison, Elaine B, Jagodzinski, Linda L, Peel, Sheila A, Khreiss, Mohammad, D'Aquila, Richard T, Casares, Sofia, Rao, Mangala, Connick, Elizabeth

“…A major barrier in the use of humanized mice as models of HIV-1 (HIV) infection is the inadequate generation of virus-specific antibody responses. Humanized…”
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Generation and testing anti-influenza human monoclonal antibodies in a new humanized mouse model (DRAGA: HLA-A2. HLA-DR4. Rag1 KO. IL-2Rγc KO. NOD) by Mendoza, Mirian, Ballesteros, Angela, Qiu, Qi, Pow Sang, Luis, Shashikumar, Soumya, Casares, Sofia, Brumeanu, Teodor-D.

“…Pandemic outbreaks of influenza type A viruses have resulted in numerous fatalities around the globe. Since the conventional influenza vaccines (CIV) provide…”
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Dissemination of Orientia tsutsugamushi , a Causative Agent of Scrub Typhus, and Immunological Responses in the Humanized DRAGA Mouse by Jiang, Le, Morris, Erin K, Aguilera-Olvera, Rodrigo, Zhang, Zhiwen, Chan, Teik-Chye, Shashikumar, Soumya, Chao, Chien-Chung, Casares, Sofia A, Ching, Wei-Mei

“…Scrub typhus is caused by , an obligated intracellular bacterium that affects over one million people per year. Several mouse models have been used to study…”
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Differential effect of HLA class-I versus class-II transgenes on human T and B cell reconstitution and function in NRG mice by Majji, Sai, Wijayalath, Wathsala, Shashikumar, Soumya, Pow-Sang, Luis, Villasante, Eileen, Brumeanu, Teodor D., Casares, Sofia

“…Humanized mice expressing Human Leukocyte Antigen (HLA) class I or II transgenes have been generated, but the role of class I vs class II on human T and B cell…”
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Improving vector-borne pathogen surveillance: A laboratory-based study exploring the potential to detect dengue virus and malaria parasites in mosquito saliva by Melanson, Vanessa, Jochim, Ryan, Yarnell, Michael, Ferlez, Karen, Shashikumar, Soumya, Richardson, Jason

“…Background & objectives: Vector-borne pathogen surveillance programmes typically rely on the collection of large numbers of potential vectors followed by…”
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