Search Results - "Sharypova, Ekaterina"
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Transcription Factors as Important Regulators of Changes in Behavior through Domestication of Gray Rats: Quantitative Data from RNA Sequencing
Published in International journal of molecular sciences (14-10-2022)“…Studies on hereditary fixation of the tame-behavior phenotype during animal domestication remain relevant and important because they are of both basic research…”
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Plant_SNP_TATA_Z-Tester: A Web Service That Unequivocally Estimates the Impact of Proximal Promoter Mutations on Plant Gene Expression
Published in International journal of molecular sciences (04-08-2022)“…Synthetic targeted optimization of plant promoters is becoming a part of progress in mainstream postgenomic agriculture along with hybridization of cultivated…”
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AtSNP_TATAdb: Candidate Molecular Markers of Plant Advantages Related to Single Nucleotide Polymorphisms within Proximal Promoters of Arabidopsis thaliana L
Published in International journal of molecular sciences (03-01-2024)“…The mainstream of the post-genome target-assisted breeding in crop plant species includes biofortification such as high-throughput phenotyping along with…”
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Stress Reactivity, Susceptibility to Hypertension, and Differential Expression of Genes in Hypertensive Compared to Normotensive Patients
Published in International journal of molecular sciences (04-03-2022)“…Although half of hypertensive patients have hypertensive parents, known hypertension-related human loci identified by genome-wide analysis explain only 3% of…”
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Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters
Published in BMC genomics (09-02-2018)“…The progress of medicine, science, technology, education, and culture improves, year by year, quality of life and life expectancy of the populace. The modern…”
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A Bioinformatics Model of Human Diseases on the Basis of Differentially Expressed Genes (of Domestic Versus Wild Animals) That Are Orthologs of Human Genes Associated with Reproductive-Potential Changes
Published in International journal of molecular sciences (26-02-2021)“…Earlier, after our bioinformatic analysis of single-nucleotide polymorphisms of TATA-binding protein-binding sites within gene promoters on the human Y…”
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Unannotated single nucleotide polymorphisms in the TATA box of erythropoiesis genes show in vitro positive involvements in cognitive and mental disorders
Published in BMC medical genetics (22-10-2020)“…Hemoglobin is a tetramer consisting of two α-chains and two β-chains of globin. Hereditary aberrations in the synthesis of one of the globin chains are at the…”
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Candidate SNP Markers of Atherogenesis Significantly Shifting the Affinity of TATA-Binding Protein for Human Gene Promoters show stabilizing Natural Selection as a Sum of Neutral Drift Accelerating Atherogenesis and Directional Natural Selection Slowing It
Published in International journal of molecular sciences (05-02-2020)“…(1) Background: The World Health Organization (WHO) regards atherosclerosis-related myocardial infarction and stroke as the main causes of death in humans…”
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A Rat Model of Human Behavior Provides Evidence of Natural Selection Against Underexpression of Aggressiveness-Related Genes in Humans
Published in Frontiers in genetics (13-12-2019)“…Aggressiveness is a hereditary behavioral pattern that forms a social hierarchy and affects the individual social rank and accordingly quality and duration of…”
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Disruptive Selection of Human Immunostimulatory and Immunosuppressive Genes Both Provokes and Prevents Rheumatoid Arthritis, Respectively, as a Self-Domestication Syndrome
Published in Frontiers in genetics (22-06-2021)“…Using our previously published Web service SNP_TATA_Comparator, we conducted a genome-wide study of single-nucleotide polymorphisms (SNPs) within core…”
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Candidate SNP markers of aggressiveness-related complications and comorbidities of genetic diseases are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters
Published in BMC genomics (28-12-2016)“…Aggressiveness in humans is a hereditary behavioral trait that mobilizes all systems of the body-first of all, the nervous and endocrine systems, and then the…”
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Natural Selection Equally Supports the Human Tendencies in Subordination and Domination: A Genome-Wide Study With in silico Confirmation and in vivo Validation in Mice
Published in Frontiers in genetics (20-02-2019)“…We proposed the following heuristic decision-making rule: "IF {an excess of a protein relating to the nervous system is an experimentally known physiological…”
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Candidate SNP Markers of Familial and Sporadic Alzheimer's Diseases Are Predicted by a Significant Change in the Affinity of TATA-Binding Protein for Human Gene Promoters
Published in Frontiers in aging neuroscience (20-07-2017)“…While year after year, conditions, quality, and duration of human lives have been improving due to the progress in science, technology, education, and…”
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Disruptive natural selection by male reproductive potential prevents underexpression of protein-coding genes on the human Y chromosome as a self-domestication syndrome
Published in BMC genetics (22-10-2020)“…In population ecology, the concept of reproductive potential denotes the most vital indicator of chances to produce and sustain a healthy descendant until…”
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AtSNP_TATAdb: Candidate Molecular Markers of Plant Advantages Related to Single Nucleotide Polymorphisms within Proximal Promoters of IArabidopsis thaliana/I L
Published in International journal of molecular sciences (01-01-2024)“…The mainstream of the post-genome target-assisted breeding in crop plant species includes biofortification such as high-throughput phenotyping along with…”
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Candidate SNP Markers of Chronopathologies Are Predicted by a Significant Change in the Affinity of TATA-Binding Protein for Human Gene Promoters
Published in BioMed research international (01-01-2016)“…Variations in human genome (e.g., single nucleotide polymorphisms, SNPs) may be associated with hereditary diseases, their complications, comorbidities, and…”
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SNP_TATA_Comparator: genomewide landmarks for preventive personalized medicine
Published in Frontiers in bioscience (Scholar edition) (01-06-2017)“…Year after year, conditions, quality, and duration of human lives have been improving due to the progress of science, technology, education, and medicine,…”
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