Search Results - "Sharpe, Daniel J."

Approximating the Shifted Hartree-Exchange-Correlation Potential in Direct Energy Kohn–Sham Theory by Sharpe, Daniel J, Levy, Mel, Tozer, David J

“…Levy and Zahariev [Phys. Rev. Lett. 113 113002 (2014)] have proposed a new approach for performing density functional theory calculations, termed direct energy…”
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POU2F1 activity regulates HOXD10 and HOXD11 promoting a proliferative and invasive phenotype in head and neck cancer by Sharpe, Daniel J, Orr, Katy S, Moran, Michael, White, Sharon J, McQuaid, Stephen, Lappin, Terence R, Thompson, Alexander, James, Jacqueline A

“…HOX genes are master regulators of organ morphogenesis and cell differentiation during embryonic development, and continue to be expressed throughout…”
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Entinostat Prevents Leukemia Maintenance in a Collaborating Oncogene‐Dependent Model of Cytogenetically Normal Acute Myeloid Leukemia by Ramsey, Joanne M., Kettyle, Laura M.J., Sharpe, Daniel J., Mulgrew, Nuala M., Dickson, Glenda J., Bijl, Janet J., Austin, Pamela, Mayotte, Nadine, Cellot, Sonia, Lappin, Terence R.J., Zhang, Shu‐Dong, Mills, Ken I., Krosl, Jana, Sauvageau, Guy, Thompson, Alexander

“…The incidence of refractory acute myeloid leukemia (AML) is on the increase due in part to an aging population that fails to respond to traditional therapies…”
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Efficient and exact sampling of transition path ensembles on Markovian networks by Sharpe, Daniel J, Wales, David J

“…The problem of flickering trajectories in standard kinetic Monte Carlo (kMC) simulations prohibits sampling of the transition path ensembles (TPEs) on…”
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AKT in stromal fibroblasts controls invasion of epithelial cells by Cichon, Ann-Christin, Pickard, Adam, McDade, Simon S, Sharpe, Daniel J, Moran, Michael, James, Jacqueline A, McCance, Dennis J

“…The tumour microenvironment has an important role in cancer progression and recent reports have proposed that stromal AKT is activated and regulates…”
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Energy Landscapes and Hybridization Pathways for DNA Hexamer Duplexes by Xiao, Shiyan, Sharpe, Daniel J, Chakraborty, Debayan, Wales, David J

“…Strand hybridization is not only a fundamental molecular mechanism underlying the biological functions of nucleic acids but is also a key step in the design of…”
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Estimating Long-Term Survivorship Rates Among Patients With Resected Stage III/IV Melanoma: Analyses From CheckMate 238 and European Organization for Research and Treatment of Cancer 18071 Trials by Weber, Jeffrey S, Middleton, Mark R, Yates, Georgia, Sharpe, Daniel J, Kurt, Murat, Lobo, Maurice, Moshyk, Andriy, Vanderpuye-Orgle, Jacqueline, Mohr, Peter

“…Standard-of-care treatments for patients with resected stage III/IV melanoma include the immuno-oncology (IO) agents nivolumab (NIVO) and ipilimumab (IPI)…”
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Energy Landscapes of Deoxyxylo- and Xylo-Nucleic Acid Octamers by Sharpe, Daniel J, Röder, Konstantin, Wales, David J

“…Artificial analogues of the natural nucleic acids have attracted interest as a diverse class of information storage molecules capable of self-replication. In…”
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The matricellular protein CCN3 regulates NOTCH1 signalling in chronic myeloid leukaemia by Suresh, Sukanya, McCallum, Lynn, Crawford, Lisa J, Lu, Wan Hua, Sharpe, Daniel J, Irvine, Alexandra E

“…Deregulated NOTCH1 has been reported in lymphoid leukaemia, although its role in chronic myeloid leukaemia (CML) is not well established. We previously…”
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GATA2 regulates the erythropoietin receptor in t(12;21) ALL by Gaine, Marie E, Sharpe, Daniel J, Smith, James S, Colyer, Hilary A A, Hodges, Vivien M, Lappin, Terry R, Mills, Ken I

“…The t(12;21) (p13;q22) chromosomal translocation resulting in the fusion gene is the most frequent structural cytogenetic abnormality in children with acute…”
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Detection and analysis of DNA methylation by pyrosequencing by Colyer, Hilary A A, Armstrong, Richard N, Sharpe, Daniel J, Mills, Ken I

“…Pyrosequencing is a "sequencing by synthesis" technique which can be used to quantify DNA methylation at specific CpG sites within the target region of…”
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The matricellular protein CCN3 regulates NOTCH1 signalling in chronic myeloid leukaemia: NOTCH1-CCN3 signalling in CML by Suresh, Sukanya, McCallum, Lynn, Crawford, Lisa J, Lu, Wan Hua, Sharpe, Daniel J, Irvine, Alexandra E

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Epigenetic Silencing of BCL2, ETS1, IL27RA and DICER1 in Low-Risk MDS Patients by del Rey, Mónica, O'Hagan, Kathleen, Dellett, Margaret, Aibar, Sara, Colyer, Hilary A.A., Alonso, María Eugenia, Diez-Campelo, María, Armstrong, Richard N., Sharpe, Daniel J., Gutiérrez, Norma C., García, Juan Luis, de las Rivas, Javier, Mills, Ken I, Hernández-Rivas, Jesús M.

“…Abstract 1704 Gene expression profiling studies have been performed in MDS to better characterize these diseases. However, the molecular pathogenesis of…”
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Stochastic paths controlling speed and dissipation by Bone, Rebecca A, Sharpe, Daniel J, Wales, David J, Green, Jason R

“…Near equilibrium, thermodynamic intuition suggests that fast, irreversible processes will dissipate more energy and entropy than slow, quasistatic processes…”
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Energy landscapes and dynamics of xylo-nucleic acids by Sharpe, Daniel J, Roeder, Konstantin, Wales, David J

“…Artificial analogues of the natural nucleic acids have attracted recent interest as a diverse class of information storage molecules capable of…”
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