Search Results - "Sharp, S"

LRP-1-mediated intracellular antibody delivery to the Central Nervous System by Tian, Xiaohe, Nyberg, Sophie, Sharp, Paul S., Madsen, Jeppe, Daneshpour, Nooshin, Armes, Steven P., Berwick, Jason, Azzouz, Mimoun, Shaw, Pamela, Abbott, N. Joan, Battaglia, Giuseppe

“…The blood-brain barrier (BBB) is by far the most important target in developing new approaches to improve delivery of drugs and diagnostic tools into the…”
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Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives by Tandon, Ritesh, Sharp, Joshua S, Zhang, Fuming, Pomin, Vitor H, Ashpole, Nicole M, Mitra, Dipanwita, McCandless, Martin G, Jin, Weihua, Liu, Hao, Sharma, Poonam, Linhardt, Robert J

“…Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has caused a pandemic of historic proportions and continues to spread globally, with…”
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Premenopausal abnormal uterine bleeding and risk of endometrial cancer by Pennant, ME, Mehta, R, Moody, P, Hackett, G, Prentice, A, Sharp, SJ, Lakshman, R

“…Background Endometrial biopsies are undertaken in premenopausal women with abnormal uterine bleeding but the risk of endometrial cancer or atypical hyperplasia…”
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Farm persistence and adaptation at the rural–urban interface: Succession and farm adjustment by Inwood, Shoshanah M., Sharp, Jeff S.

“…Despite assumptions that agriculture will automatically go into a mode of decline at the Rural Urban Interface (RUI), official statistics suggest that…”
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Quantitative Protein Topography Measurements by High Resolution Hydroxyl Radical Protein Footprinting Enable Accurate Molecular Model Selection by Xie, Boer, Sood, Amika, Woods, Robert J., Sharp, Joshua S.

“…We report an integrated workflow that allows mass spectrometry-based high-resolution hydroxyl radical protein footprinting (HR-HRPF) measurements to accurately…”
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Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals by Finucane, F. M, Luan, J, Wareham, N. J, Sharp, S. J, O'Rahilly, S, Balkau, B, Flyvbjerg, A, Walker, M, Højlund, K, Nolan, J. J, Savage, D. B

“…Aims/hypothesis Obesity is the dominant cause of insulin resistance. In adult humans it is characterised by a combination of adipocyte hypertrophy and, to a…”
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Interventional therapies for pulmonary embolism by Götzinger, Felix, Lauder, Lucas, Sharp, Andrew S. P., Lang, Irene M., Rosenkranz, Stephan, Konstantinides, Stavros, Edelman, Elazer R., Böhm, Michael, Jaber, Wissam, Mahfoud, Felix

“…Pulmonary embolism (PE) is the leading cause of in-hospital death and the third most frequent cause of cardiovascular death. The clinical presentation of PE is…”
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Cardiovascular risk assessment scores for people with diabetes: a systematic review by Chamnan, P, Simmons, R. K, Sharp, S. J, Griffin, S. J, Wareham, N. J

“…People with type 2 diabetes have an increased risk of cardiovascular disease (CVD). Multivariate cardiovascular risk scores have been used in many countries to…”
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Effects of Substrate Constraint on Crack Pattern Formation in Thin Films of Colloidal Polystyrene Particles by Smith, M. I, Sharp, J. S

“…Crack formation and the evolution of stress in drying films of colloidal particles were studied using optical microscopy and a modified cantilever deflection…”
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Renal denervation in the management of hypertension in adults. A clinical consensus statement of the ESC Council on Hypertension and the European Association of Percutaneous Cardiovascular Interventions (EAPCI) by Barbato, Emanuele, Azizi, Michel, Schmieder, Roland E, Lauder, Lucas, Böhm, Michael, Brouwers, Sofie, Bruno, Rosa Maria, Dudek, Dariusz, Kahan, Thomas, Kandzari, David E, Lüscher, Thomas F, Parati, Gianfranco, Pathak, Atul, Ribichini, Flavio L, Schlaich, Markus P, Sharp, Andrew S P, Sudano, Isabella, Volpe, Massimo, Tsioufis, Costas, Wijns, William, Mahfoud, Felix

“…Abstract Since the publication of the 2018 European Society of Cardiology/European Society of Hypertension (ESC/ESH) Guidelines for the Management of Arterial…”
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Large grazers suppress a foundational plant and reduce soil carbon concentration in eastern US saltmarshes by Sharp, S. J., Davidson, K. E., Angelini, C., Fischman, H. S., Pennings, S., Fowler, M. S., Griffin, J. N.

“…Large grazers modify vegetated ecosystems and are increasingly viewed as keystone species in trophic rewilding schemes. Yet, as their ecosystem influences are…”
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Adiposity and grip strength as long-term predictors of objectively measured physical activity in 93 015 adults: the UK Biobank study by Kim, Y, White, T, Wijndaele, K, Sharp, S J, Wareham, N J, Brage, S

“…Background/Objectives: Fatness and fitness are associated with physical activity (PA) but less is known about the prospective associations of adiposity and…”
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Complement factor I: Regulatory nexus, driver of immunopathology, and therapeutic by Hallam, T.M., Sharp, S.J., Andreadi, A., Kavanagh, D.

“…Complement factor I (FI) is the nexus for classical, lectin and alternative pathway complement regulation. FI is an 88 kDa plasma protein that circulates in an…”
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Gross and histopathologic diagnoses from North Atlantic right whale Eubalaena glacialis mortalities between 2003 and 2018 by Sharp, S M, McLellan, W A, Rotstein, D S, Costidis, A M, Barco, S G, Durham, K, Pitchford, T D, Jackson, K A, Daoust, P-Y, Wimmer, T, Couture, E L, Bourque, L, Frasier, T, Frasier, B, Fauquier, D, Rowles, T K, Hamilton, P K, Pettis, H, Moore, M J

“…Seventy mortalities of North Atlantic right whales Eubalaena glacialis (NARW) were documented between 2003 and 2018 from Florida, USA, to the Gulf of St…”
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The link between family history and risk of type 2 diabetes is not explained by anthropometric, lifestyle or genetic risk factors: the EPIC-InterAct study by Scott, R A, Langenberg, C, Sharp, S J, Franks, P W, Rolandsson, O, Drogan, D, van der Schouw, Y T, Ekelund, U, Kerrison, N D, Ardanaz, E, Arriola, L, Balkau, B, Barricarte, A, Barroso, I, Bendinelli, B, Beulens, J W J, Boeing, H, de Lauzon-Guillain, B, Deloukas, P, Fagherazzi, G, Gonzalez, C, Griffin, S J, Groop, L C, Halkjaer, J, Huerta, J M, Kaaks, R, Khaw, K T, Krogh, V, Nilsson, P M, Norat, T, Overvad, K, Panico, S, Rodriguez-Suarez, L, Romaguera, D, Romieu, I, Sacerdote, C, Sánchez, M J, Spijkerman, A M W, Teucher, B, Tjonneland, A, Tumino, R, van der A, D L, Wark, P A, McCarthy, M I, Riboli, E, Wareham, N J

“…Aims/hypothesis Although a family history of type 2 diabetes is a strong risk factor for the disease, the factors mediating this excess risk are poorly…”
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Ultrasound-facilitated, catheter-directed thrombolysis vs anticoagulation alone for acute intermediate-high-risk pulmonary embolism: Rationale and design of the HI-PEITHO study by Klok, Frederikus A., Piazza, Gregory, Sharp, Andrew S.P., Ní Ainle, Fionnuala, Jaff, Michael R., Chauhan, Nikhil, Patel, Binal, Barco, Stefano, Goldhaber, Samuel Z., Kucher, Nils, Lang, Irene M., Schmidtmann, Irene, Sterling, Keith M., Becker, Dorothea, Martin, Nadine, Rosenfield, Kenneth, Konstantinides, Stavros V.

“…Due to the bleeding risk of full-dose systemic thrombolysis and the lack of major trials focusing on the clinical benefits of catheter-directed treatment,…”
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Vehicle dynamics applications of optimal control theory by Sharp, R. S., Peng, Huei

“…The aim of the paper is to survey the various forms of optimal-control theory which have been applied to automotive problems and to present illustrative…”
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Fast Photochemical Oxidation of Protein Footprints Faster than Protein Unfolding by Gau, Brian C, Sharp, Joshua S, Rempel, Don L, Gross, Michael L

“…Fast photochemical oxidation of proteins (FPOP) is a chemical footprinting method whereby exposed amino-acid residues are covalently labeled by oxidation with…”
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Lysosomal enzyme binding to the cation-independent mannose 6-phosphate receptor is regulated allosterically by insulin-like growth factor 2 by Bohnsack, Richard N., Misra, Sandeep K., Liu, Jianfang, Ishihara-Aoki, Mayumi, Pereckas, Michaela, Aoki, Kazuhiro, Ren, Gang, Sharp, Joshua S., Dahms, Nancy M.

“…The cation-independent mannose 6-phosphate receptor (CI-MPR) is clinically significant in the treatment of patients with lysosomal storage diseases because it…”
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Bidirectional association between physical activity and muscular strength in older adults: Results from the UK Biobank study by Cooper, Ajm, Lamb, Mje, Sharp, S J, Simmons, R K, Griffin, S J

“…The relationship between physical activity and muscular strength has not been examined in detail among older adults. The objective of this study was to examine…”
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