Search Results - "Sharp, P P"

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    Deep surface rolling for fatigue life enhancement of laser clad aircraft aluminium alloy by Zhuang, W., Liu, Q., Djugum, R., Sharp, P.K., Paradowska, A.

    Published in Applied surface science (30-11-2014)
    “…•Deep surface rolling as a post-repair enhancement technology was applied to the laser cladded 7075-T651 aluminium alloy specimens that simulated corrosion…”
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    Key Aspects of Neurovascular Control Mediated by Specific Populations of Inhibitory Cortical Interneurons by Lee, L, Boorman, L, Glendenning, E, Christmas, C, Sharp, P, Redgrave, P, Shabir, O, Bracci, E, Berwick, J, Howarth, C

    Published in Cerebral cortex (New York, N.Y. 1991) (14-04-2020)
    “…Abstract Inhibitory interneurons can evoke vasodilation and vasoconstriction, making them potential cellular drivers of neurovascular coupling. However, the…”
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    RNA interference--2001 by Sharp, P A

    Published in Genes & development (01-03-2001)
    “…In the few years since the discovery of RNA interference (RNAi), it has become clear that this process is ancient. RNAi, the oldest and most ubiquitous…”
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    The performance of the N-body integrator SSS by Sharp, P. W.

    Published in Numerical algorithms (01-08-2019)
    “…The integrator SSS performs accurate N -body simulations of the Solar System when there is a mix of massive bodies and test particles. The orbital motion of…”
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    Evidence for elevated mutation rates in low-quality genotypes by Sharp, Nathaniel P, Agrawal, Aneil F

    “…The deleterious mutation rate plays a key role in a number of important topics in biology, from mating system evolution to human health. Despite this broad…”
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    BET bromodomain inhibitors: a patent review by Garnier, Jean-Marc, Sharp, Phillip P, Burns, Christopher J

    Published in Expert opinion on therapeutic patents (01-02-2014)
    “…The bromodomain (BRD) and extra-C terminal domain (BET) protein family consists of four members (BRD2, BRD3, BRD4 and BRDT). These "epigenetic readers" bind to…”
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    BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and transformed hematopoietic cells by Xu, Z, Sharp, P P, Yao, Y, Segal, D, Ang, C H, Khaw, S L, Aubrey, B J, Gong, J, Kelly, G L, Herold, M J, Strasser, A, Roberts, A W, Alexander, W S, Burns, C J, Huang, D C S, Glaser, S P

    Published in Leukemia (01-07-2016)
    “…The BET ( b romodomain and e xtra t erminal domain) bromodomain-containing proteins, such as BRD4, are highly promising targets for treating lymphoid and…”
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    Low Genetic Quality Alters Key Dimensions of the Mutational Spectrum by Sharp, Nathaniel P, Agrawal, Aneil F

    Published in PLoS biology (25-03-2016)
    “…Mutations affect individual health, population persistence, adaptation, diversification, and genome evolution. There is evidence that the mutation rate varies…”
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    Gene silencing in mammals by small interfering RNAs by McManus, Michael T, Sharp, Phillip A

    Published in Nature reviews. Genetics (01-10-2002)
    “…Among the 3 billion base pairs of the human genome, there are approximately 30,000-40,000 protein-coding genes, but the function of at least half of them…”
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    Improving wheat as a source of iron and zinc for global nutrition by Balk, J., Connorton, J. M., Wan, Y., Lovegrove, A., Moore, K. L., Uauy, C., Sharp, P. A., Shewry, P. R.

    Published in Nutrition bulletin (01-03-2019)
    “…Wheat is the staple food crop in temperate countries and increasingly consumed in developing countries, displacing traditional foods. However, wheat products…”
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    Review: Neuropathology and behavioural features of transgenic murine models of Alzheimer's disease by Ameen‐Ali, K. E., Wharton, S. B., Simpson, J. E., Heath, P. R., Sharp, P., Berwick, J.

    Published in Neuropathology and applied neurobiology (01-12-2017)
    “…Our understanding of the underlying biology of Alzheimer's disease (AD) has been steadily progressing; however, this is yet to translate into a successful…”
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    Metric space formulation of quantum mechanical conservation laws by Sharp, P. M., D'Amico, I.

    “…We show that conservation laws in quantum mechanics naturally lead to metric spaces for the set of related physical quantities. All such metric spaces have an…”
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    Can pitting corrosion change the location of fatigue failures in aircraft? by Crawford, Bruce R., Loader, Chris, Liu, Qianchu, Harrison, Timothy J., Sharp, P. Khan

    Published in International journal of fatigue (01-04-2014)
    “…•A Monte Carlo model was developed to predict the fatigue life of 7010-T7651.•The material was modeled as low-kt specimens in pitted and uncorroded states.•It…”
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