Search Results - "Sharova, Lioudmila"

Identification of Pou5f1, Sox2, and Nanog downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data by Sharov, Alexei A, Masui, Shinji, Sharova, Lioudmila V, Piao, Yulan, Aiba, Kazuhiro, Matoba, Ryo, Xin, Li, Niwa, Hitoshi, Ko, Minoru S H

“…Target genes of a transcription factor (TF) Pou5f1 (Oct3/4 or Oct4), which is essential for pluripotency maintenance and self-renewal of embryonic stem (ES)…”
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Zscan4 regulates telomere elongation and genomic stability in ES cells by Ko, Minoru S. H, Zalzman, Michal, Falco, Geppino, Sharova, Lioudmila V, Nishiyama, Akira, Thomas, Marshall, Lee, Sung-Lim, Stagg, Carole A, Hoang, Hien G, Yang, Hsih-Te, Indig, Fred E, Wersto, Robert P

“…Exceptional genomic stability is one of the hallmarks of mouse embryonic stem (ES) cells. However, the genes contributing to this stability remain obscure. We…”
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Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells by Landry, Joseph, Sharov, Alexei A, Piao, Yulan, Sharova, Lioudmila V, Xiao, Hua, Southon, Eileen, Matta, Jennifer, Tessarollo, Lino, Zhang, Ying E, Ko, Minoru S H, Kuehn, Michael R, Yamaguchi, Terry P, Wu, Carl

“…We have characterized the biological functions of the chromatin remodeling protein Bptf (Bromodomain PHD-finger Transcription Factor), the largest subunit of…”
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Database for mRNA Half-Life of 19 977 Genes Obtained by DNA Microarray Analysis of Pluripotent and Differentiating Mouse Embryonic Stem Cells by Sharova, Lioudmila V., Sharov, Alexei A., Nedorezov, Timur, Piao, Yulan, Shaik, Nabeebi, Ko, Minoru S.H.

“…Degradation of mRNA is one of the key processes that control the steady-state level of gene expression. However, the rate of mRNA decay for the majority of…”
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Zscan4 restores the developmental potency of embryonic stem cells by Amano, Tomokazu, Hirata, Tetsuya, Falco, Geppino, Monti, Manuela, Sharova, Lioudmila V., Amano, Misa, Sheer, Sarah, Hoang, Hien G., Piao, Yulan, Stagg, Carole A., Yamamizu, Kohei, Akiyama, Tomohiko, Ko, Minoru S. H.

“…The developmental potency of mouse embryonic stem (ES) cells, which is the ability to contribute to a whole embryo, is known to deteriorate during long-term…”
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BAF250B‐Associated SWI/SNF Chromatin‐Remodeling Complex Is Required to Maintain Undifferentiated Mouse Embryonic Stem Cells by Yan, Zhijiang, Wang, Zhong, Sharova, Lioudmila, Sharov, Alexei A., Ling, Chen, Piao, Yulan, Aiba, Kazuhiro, Matoba, Ryo, Wang, Weidong, Ko, Minoru S. H.

“…Whether SWI/SNF chromatin remodeling complexes play roles in embryonic stem (ES) cells remains unknown. Here we show that SWI/SNF complexes are present in…”
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Uncovering Early Response of Gene Regulatory Networks in ESCs by Systematic Induction of Transcription Factors by Nishiyama, Akira, Xin, Li, Sharov, Alexei A., Thomas, Marshall, Mowrer, Gregory, Meyers, Emily, Piao, Yulan, Mehta, Samir, Yee, Sarah, Nakatake, Yuhki, Stagg, Carole, Sharova, Lioudmila, Correa-Cerro, Lina S., Bassey, Uwem, Hoang, Hien, Kim, Eugene, Tapnio, Richard, Qian, Yong, Dudekula, Dawood, Zalzman, Michal, Li, Manxiang, Falco, Geppino, Yang, Hsih-Te, Lee, Sung-Lim, Monti, Manuela, Stanghellini, Ilaria, Islam, Md. Nurul, Nagaraja, Ramaiah, Goldberg, Ilya, Wang, Weidong, Longo, Dan L., Schlessinger, David, Ko, Minoru S.H.

“…To examine transcription factor (TF) network(s), we created mouse ESC lines, in each of which 1 of 50 TFs tagged with a FLAG moiety is inserted into a…”
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Emergence of undifferentiated colonies from mouse embryonic stem cells undergoing differentiation by retinoic acid treatment by Sharova, Lioudmila V., Sharov, Alexei A., Piao, Yulan, Stagg, Carole A., Amano, Tomokazu, Qian, Yong, Dudekula, Dawood, Schlessinger, David, Ko, Minoru S. H.

“…Retinoic acid (RA) is one of the most potent inducers of differentiation of mouse embryonic stem cells (ESCs). However, previous studies show that RA treatment…”
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Global gene expression profiling reveals similarities and differences among mouse pluripotent stem cells of different origins and strains by Sharova, Lioudmila V., Sharov, Alexei A., Piao, Yulan, Shaik, Nabeebi, Sullivan, Terry, Stewart, Colin L., Hogan, Brigid L.M., Ko, Minoru S.H.

“…Pluripotent stem cell lines with similar phenotypes can be derived from both blastocysts (embryonic stem cells, ESC) and primordial germ cells (embryonic germ…”
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Systematic repression of transcription factors reveals limited patterns of gene expression changes in ES cells by Nishiyama, Akira, Sharov, Alexei A., Piao, Yulan, Amano, Misa, Amano, Tomokazu, Hoang, Hien G., Binder, Bernard Y., Tapnio, Richard, Bassey, Uwem, Malinou, Justin N., Correa-Cerro, Lina S., Yu, Hong, Xin, Li, Meyers, Emily, Zalzman, Michal, Nakatake, Yuhki, Stagg, Carole, Sharova, Lioudmila, Qian, Yong, Dudekula, Dawood, Sheer, Sarah, Cadet, Jean S., Hirata, Tetsuya, Yang, Hsih-Te, Goldberg, Ilya, Evans, Michele K., Longo, Dan L., Schlessinger, David, Ko, Minoru S. H.

“…Networks of transcription factors (TFs) are thought to determine and maintain the identity of cells. Here we systematically repressed each of 100 TFs with…”
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Induction of specific neuron types by overexpression of single transcription factors by Teratani-Ota, Yusuke, Yamamizu, Kohei, Piao, Yulan, Sharova, Lioudmila, Amano, Misa, Yu, Hong, Schlessinger, David, Ko, Minoru S. H., Sharov, Alexei A.

“…Specific neuronal types derived from embryonic stem cells (ESCs) can facilitate mechanistic studies and potentially aid in regenerative medicine. Existing…”
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Generation of mouse ES cell lines engineered for the forced induction of transcription factors by Correa-Cerro, Lina S., Piao, Yulan, Sharov, Alexei A., Nishiyama, Akira, Cadet, Jean S., Yu, Hong, Sharova, Lioudmila V., Xin, Li, Hoang, Hien G., Thomas, Marshall, Qian, Yong, Dudekula, Dawood B., Meyers, Emily, Binder, Bernard Y., Mowrer, Gregory, Bassey, Uwem, Longo, Dan L., Schlessinger, David, Ko, Minoru S. H.

“…Here we report the generation and characterization of 84 mouse ES cell lines with doxycycline-controllable transcription factors (TFs) which, together with the…”
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An in situ hybridization-based screen for heterogeneously expressed genes in mouse ES cells by Carter, Mark G., Stagg, Carole A., Falco, Geppino, Yoshikawa, Toshiyuki, Bassey, Uwem C., Aiba, Kazuhiro, Sharova, Lioudmila V., Shaik, Nabeebi, Ko, Minoru S.H.

“…We previously reported that Zscan4 showed heterogeneous expression patterns in mouse embryonic stem (ES) cells. To identify genes that show similar expression…”
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Defining Developmental Potency and Cell Lineage Trajectories by Expression Profiling of Differentiating Mouse Embryonic Stem Cells by Aiba, Kazuhiro, Nedorezov, Timur, Piao, Yulan, Nishiyama, Akira, Matoba, Ryo, Sharova, Lioudmila V., Sharov, Alexei A., Yamanaka, Shinya, Niwa, Hitoshi, Ko, Minoru S. H.

“…Biologists rely on morphology, function and specific markers to define the differentiation status of cells. Transcript profiling has expanded the repertoire of…”
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Generation of mouse ES cell lines engineered for the forced induction of transcription factors by Correa-Cerro, Lina S., Piao, Yulan, Sharov, Alexei A., Nishiyama, Akira, Cadet, Jean S., Yu, Hong, Sharova, Lioudmila V., Xin, Li, Hoang, Hien G., Thomas, Marshall, Qian, Yong, Dudekula, Dawood B., Meyers, Emily, Binder, Bernard Y., Mowrer, Gregory, Bassey, Uwem, Longo, Dan L., Schlessinger, David, Ko, Minoru S. H.

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Esg1, expressed exclusively in preimplantation embryos, germline, and embryonic stem cells, is a putative RNA‐binding protein with broad RNA targets by Tanaka, Tetsuya S., Lopez de Silanes, Isabel, Sharova, Lioudmila V., Akutsu, Hidenori, Yoshikawa, Toshiyuki, Amano, Hisayuki, Yamanaka, Shinya, Gorospe, Myriam, Ko, Minoru S. H.

“…In our earlier attempt to identify genes involved in the maintenance of cellular pluripotency, we found that KH‐domain protein Embryonal stem cell‐specific…”
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Evolutionary implications of substitution patterns in prolamin genes of Oryza glaberrima (African rice, Poaceae) and related species by Hilu, Khidir W., Sharova, Lioudmila V.

“…Patterns of sequence variation of nuclear genes encoding 10-kDa and 16-kDa prolamin seed storage proteins were examined in Oryza glaberrima (African rice,…”
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Functional and Ultrastructural Cell Pathology Induced by Fuel Oil in Cultured Dolphin Renal Cells by Pfeiffer, Carl J., Sharova, Lioudmila V., Gray, Lucy

“…Investigations were undertaken to elucidate in a marine mammal renal cell culture system the toxicity and some of the mechanisms of cytopathology in a…”
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Characterization of 10 KDA prolamin genes in Phyllostachys aurea (Bambusoideae, Poaceae) by Hilu, Khidir W., Sharova, Lioudmila V.

“…Prolamin is the dominant class of seed storage protein in grasses (Poaceae). Information on the 10 kDa multigene family coding for prolamins characteristic of…”
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Transcriptome analysis of mouse stem cells and early embryos by Sharov, Alexei A, Piao, Yulan, Matoba, Ryo, Dudekula, Dawood B, Qian, Yong, VanBuren, Vincent, Falco, Geppino, Martin, Patrick R, Stagg, Carole A, Bassey, Uwem C, Wang, Yuxia, Carter, Mark G, Hamatani, Toshio, Aiba, Kazuhiro, Akutsu, Hidenori, Sharova, Lioudmila, Tanaka, Tetsuya S, Kimber, Wendy L, Yoshikawa, Toshiyuki, Jaradat, Saied A, Pantano, Serafino, Nagaraja, Ramaiah, Boheler, Kenneth R, Taub, Dennis, Hodes, Richard J, Longo, Dan L, Schlessinger, David, Keller, Jonathan, Klotz, Emily, Kelsoe, Garnett, Umezawa, Akihiro, Vescovi, Angelo L, Rossant, Janet, Kunath, Tilo, Hogan, Brigid L M, Curci, Anna, D'Urso, Michele, Kelso, Janet, Hide, Winston, Ko, Minoru S H

“…Understanding and harnessing cellular potency are fundamental in biology and are also critical to the future therapeutic use of stem cells. Transcriptome…”
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